8Q0N

HACE1 in complex with RAC1 Q61L

This is a non-PDB format compatible entry.

Summary for 8Q0N

• Entry DOI: 10.2210/pdb8q0n/pdb
• Related: 8PWL
• EMDB information: 18056
• Descriptor: E3 ubiquitin-protein ligase HACE1, Ras-related C3 botulinum toxin substrate 1, iodoacetic acid, ... (4 entities in total)
• Functional Keywords: e3, ubiquitin ligase, small gtpase, crosslink, sia, ligase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 124409.46

Authors

Wolter, M.,Duering, J.,Dienemann, C.,Lorenz, S. (deposition date: 2023-07-28, release date: 2024-01-10, Last modification date: 2024-02-28)

• Primary citation: During, J.,Wolter, M.,Toplak, J.J.,Torres, C.,Dybkov, O.,Fokkens, T.J.,Bohnsack, K.E.,Urlaub, H.,Steinchen, W.,Dienemann, C.,Lorenz, S.; Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1.; Nat.Struct.Mol.Biol., 31:364-377, 2024; PubMed: 38332367; DOI: 10.1038/s41594-023-01203-4

Experimental method

ELECTRON MICROSCOPY (4.2 Å)