6J24
Crystal structure of a SAM-dependent methyltransferase LepI in complex with its substrate
Summary for 6J24
Entry DOI | 10.2210/pdb6j24/pdb |
Descriptor | O-methyltransferase, (3~{S},4'~{R},4'~{a}~{S},6'~{R},8'~{a}~{S})-4',6'-dimethyl-5-phenyl-spiro[1~{H}-pyridine-3,5'-2,3,4,4~{a},6,8~{a}-hexahydro-1~{H}-naphthalene]-2,4-dione, S-ADENOSYLMETHIONINE, ... (4 entities in total) |
Functional Keywords | complex, transferase |
Biological source | Aspergillus flavus |
Total number of polymer chains | 2 |
Total formula weight | 88196.74 |
Authors | |
Primary citation | Sun, Q.,Hu, Y.,Gu, Y.,Huang, J.,He, J.,Luo, L.,Yang, Y.,Yin, S.,Dou, C.,Wang, T.,Fu, X.,He, L.,Qi, S.,Zhu, X.,Yang, S.,Wei, X.,Cheng, W. Deciphering the regulatory and catalytic mechanisms of an unusual SAM-dependent enzyme. Signal Transduct Target Ther, 4:17-17, 2019 Cited by PubMed: 31149354DOI: 10.1038/s41392-019-0052-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.244 Å) |
Structure validation
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