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8B02
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BU of 8b02 by Molmil
Crystal structure of the dsRBD domain of tRNA-dihydrouridine(20) synthase from Amphimedon queenslandica
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, DRBM domain-containing protein, ...
著者Pecqueur, L, Faivre, B, Hamdane, D.
登録日2022-09-07
公開日2022-11-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.676 Å)
主引用文献Evolutionary Diversity of Dus2 Enzymes Reveals Novel Structural and Functional Features among Members of the RNA Dihydrouridine Synthases Family.
Biomolecules, 12, 2022
3C88
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BU of 3c88 by Molmil
Crystal structure of the catalytic domain of botulinum neurotoxin serotype A with inhibitory peptide RRGC
分子名称: Botulinum neurotoxin A light chain, Inhibitor peptide RRGC, SODIUM ION, ...
著者Kumaran, D, Swaminathan, S.
登録日2008-02-11
公開日2008-04-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure- and Substrate-based Inhibitor Design for Clostridium botulinum Neurotoxin Serotype A
J.Biol.Chem., 283, 2008
2BKW
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BU of 2bkw by Molmil
Yeast alanine:glyoxylate aminotransferase YFL030w
分子名称: ALANINE-GLYOXYLATE AMINOTRANSFERASE 1, GLYOXYLIC ACID, PYRIDOXAL-5'-PHOSPHATE
著者Meyer, P, Liger, D, Leulliot, N, Quevillon-Cheruel, S, Zhou, C.Z, Borel, F, Ferrer, J.L, Poupon, A, Janin, J, van Tilbeurgh, H.
登録日2005-02-21
公開日2005-11-02
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Crystal Structure and Confirmation of the Alanine:Glyoxylate Aminotransferase Activity of the Yfl030W Yeast Protein
Biochimie, 87, 2005
3BRH
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BU of 3brh by Molmil
Protein Tyrosine Phosphatase PTPN-22 (Lyp) bound to the mono-Phosphorylated Lck active site peptide
分子名称: Lck Active Site Peptide, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 22
著者Seidel, R.D, Love, J, Piserchio, A, Cowburn, D.
登録日2007-12-21
公開日2009-02-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Lyp/PTPN22 Phosphatase Domain: Substrate Recognition and Specificity for Src family kinases
To be Published
2BNK
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BU of 2bnk by Molmil
The structure of phage phi29 replication organizer protein p16.7
分子名称: EARLY PROTEIN GP16.7
著者Albert, A, Asensio, J.L, Munoz-Espin, D, Gonzalez, C, Hermoso, J.A, Villar, L, Jimenez-Barbero, J, Salas, M, Meijer, W.J.J.
登録日2005-03-28
公開日2005-04-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the Functional Domain of {Varphi}29 Replication Organizer: Insights Into Oligomerization and DNA Binding.
J.Biol.Chem., 280, 2005
3BIL
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BU of 3bil by Molmil
Crystal structure of a probable LacI family transcriptional regulator from Corynebacterium glutamicum
分子名称: Probable LacI-family transcriptional regulator
著者Bonanno, J.B, Freeman, J, Bain, K.T, Mendoza, M, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-11-30
公開日2007-12-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of a probable LacI family transcriptional regulator from Corynebacterium glutamicum.
To be Published
3BIX
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BU of 3bix by Molmil
Crystal structure of the extracellular esterase domain of Neuroligin-1
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, NICKEL (II) ION, ...
著者Arac, D, Boucard, A.A, Ozkan, E, Strop, P, Newell, E, Sudhof, T.C, Brunger, A.T.
登録日2007-12-01
公開日2007-12-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of Neuroligin-1 and the Neuroligin-1/Neurexin-1beta Complex Reveal Specific Protein-Protein and Protein-Ca(2+) Interactions.
Neuron, 56, 2007
2C5B
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BU of 2c5b by Molmil
X-ray crystal structure of 5'-fluorodeoxyadenosine synthase from Streptomyces cattleya complexed with 2'deoxy-5'deoxy-fluoroadenosine.
分子名称: 5'-FLUORO-2',5'-DIDEOXYADENOSINE, 5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE, METHIONINE
著者McEwan, A.R, Deng, H, McGlinchey, R.P, Robinson, D.A, O'Hagan, D, Naismith, J.H, Spencer, J.
登録日2005-10-26
公開日2007-02-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Substrate Specificity in Enzymatic Fluorination. The Fluorinase from Streptomyces Cattleya Accepts 2'-Deoxyadenosine Substrates.
Org.Biomol.Chem., 4, 2006
3BGH
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BU of 3bgh by Molmil
Crystal structure of putative neuraminyllactose-binding hemagglutinin homolog from Helicobacter pylori
分子名称: Putative neuraminyllactose-binding hemagglutinin homolog, SULFATE ION
著者Bonanno, J.B, Dickey, J, Bain, K.T, McKenzie, C, Romero, R, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-11-26
公開日2007-12-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure of putative neuraminyllactose-binding hemagglutinin homolog from Helicobacter pylori.
To be Published
8YGW
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BU of 8ygw by Molmil
The Crystal Structure of MAPK11 from Biortus
分子名称: 1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA, Mitogen-activated protein kinase 11
著者Wang, F, Cheng, W, Yuan, Z, Lin, D, Guo, S.
登録日2024-02-27
公開日2024-03-13
実験手法X-RAY DIFFRACTION (3.301 Å)
主引用文献The Crystal Structure of MAPK11 from Biortus.
To Be Published
2BUD
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BU of 2bud by Molmil
The solution structure of the chromo barrel domain from the males- absent on the first (MOF) protein
分子名称: MALES-ABSENT ON THE FIRST PROTEIN
著者Nielsen, P.R, Nietlispach, D, Buscaino, A, Warner, R.J, Akhtar, A, Murzin, A.G, Murzina, N.V, Laue, E.D.
登録日2005-06-09
公開日2005-06-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of the Chromo Barrel Domain from the Mof Acetyltransferase
J.Biol.Chem., 280, 2005
2BVB
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BU of 2bvb by Molmil
The C-terminal domain from Micronemal Protein 1 (MIC1) from Toxoplasma Gondii
分子名称: MICRONEMAL PROTEIN 1
著者Saouros, S, Edwards-Jones, B, Reiss, M, Sawmynaden, K, Cota, E, Simpson, P, Dowse, T.J, Jakle, U, Ramboarina, S, Shivarattan, T, Matthews, S, Soldati-Favre, D.
登録日2005-06-23
公開日2005-10-12
最終更新日2021-06-23
実験手法SOLUTION NMR
主引用文献A Novel Galectin-Like Domain from Toxoplasma Gondll Micronemal Protein 1 Assists the Folding, Assembly,and Transport of a Cell-Adhesion Complex.
J.Biol.Chem., 280, 2005
2BOK
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BU of 2bok by Molmil
Factor Xa - cation
分子名称: COAGULATION FACTOR X, SODIUM ION, [AMINO (4-{(3AS,4R,8AS,8BR)-1,3-DIOXO-2- [3-(TRIMETHYLAMMONIO) PROPYL]DECAHYDROPYRROLO[3,4-A] PYRROLIZIN-4-YL}PHENYL) METHYLENE]AMMONIUM
著者Morgenthaler, M, Schaerer, K, Paulini, R, Obst-Sander, U, Banner, D.W, Schlatter, D, Benz, J, Stihle, M, Diederich, F.
登録日2005-04-12
公開日2005-06-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Quantification of Cation-Pi Interactions in Protein-Ligand Complexes: Crystal-Structure Analysis of Factor Xa Bound to a Quaternary Ammonium Ion Ligand
Angew.Chem.Int.Ed.Engl., 44, 2005
3B1T
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BU of 3b1t by Molmil
Crystal structure of human peptidylarginine deiminase 4 in complex with o-Cl-amidine
分子名称: 2-{[(2S)-1-amino-5-{[(1Z)-2-chloroethanimidoyl]amino}-1-oxopentan-2-yl]carbamoyl}benzoic acid, CALCIUM ION, Protein-arginine deiminase type-4, ...
著者Causey, C.P, Jones, J.E, Slack, J.L, Kamei, D, Jones Jr, L.E, Subramanian, V, Knuckley, B, Ebrahimi, P, Chumanevich, A.A, Luo, Y, Hashimoto, H, Shimizu, T, Sato, M, Hofseth, L.J, Thompson, P.R.
登録日2011-07-13
公開日2011-10-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Development of N-alpha-(2-Carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine Amide (o-F-amidine) and N-alpha-(2-Carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine Amide (o-Cl-amidine) As Second Generation Protein Arginine Deiminase (PAD) Inhibitors
J.Med.Chem., 54, 2011
8XP5
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BU of 8xp5 by Molmil
The Crystal Structure of p53/BCL-xL fusion complex from Biortus.
分子名称: Bcl-2-like protein 1,Cellular tumor antigen p53, ZINC ION
著者Wang, F, Cheng, W, Yuan, Z, Lin, D, Bao, C.
登録日2024-01-03
公開日2024-03-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The Crystal Structure of p53/BCL-xL fusion complex from Biortus.
To Be Published
2BYO
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BU of 2byo by Molmil
Crystal structure of Mycobacterium tuberculosis lipoprotein LppX (Rv2945c)
分子名称: ACETATE ION, ALPHA-LINOLENIC ACID, D-MALATE, ...
著者Sulzenbacher, G, Canaan, S, Roig-Zamboni, V, Maurin, D, Gicquel, B, Bourne, Y.
登録日2005-08-03
公開日2006-03-22
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Lppx is a Lipoprotein Required for the Translocation of Phthiocerol Dimycocerosates to the Surface of Mycobacterium Tuberculosis.
Embo J., 25, 2006
8ASY
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BU of 8asy by Molmil
SARS-CoV-2 Omicron BA.2.75 RBD in complex with ACE2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
著者Zhou, D, Huo, J, Ren, J, Stuart, D.I.
登録日2022-08-22
公開日2023-01-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献A delicate balance between antibody evasion and ACE2 affinity for Omicron BA.2.75.
Cell Rep, 42, 2022
3UR4
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BU of 3ur4 by Molmil
Crystal structure of human WD repeat domain 5 with compound
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ...
著者Dong, A, Dombrovski, L, Senisterra, G, Wernimont, A, Wasney, G.A, Allali Hassani, A, Nguyen, K.T, Smil, D, Bolshan, Y, Hajian, T, Poda, G, Chau, I, Al-Awar, R, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Brown, P, Schapira, M, Vedadi, M, Wu, H, Structural Genomics Consortium (SGC)
登録日2011-11-21
公開日2011-12-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5.
Biochem. J., 449, 2013
8XPN
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BU of 8xpn by Molmil
The Crystal Structure of USP8 from Biortus.
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ubiquitin carboxyl-terminal hydrolase 8, ...
著者Wang, F, Cheng, W, Yuan, Z, Lin, D, Wang, J.
登録日2024-01-04
公開日2024-03-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Crystal Structure of USP8 from Biortus.
To Be Published
2BZM
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BU of 2bzm by Molmil
Solution structure of the primary host recognition region of complement factor H
分子名称: COMPLEMENT FACTOR H
著者Herbert, A.P, Uhrin, D, Lyon, M, Pangburn, M.K, Barlow, P.N.
登録日2005-08-18
公開日2006-03-22
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Disease-Associated Sequence Variations Congregate in a Polyanion Recognition Patch on Human Factor H Revealed in Three-Dimensional Structure.
J.Biol.Chem., 281, 2006
3C1H
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BU of 3c1h by Molmil
Substrate binding, deprotonation and selectivity at the periplasmic entrance of the E. coli ammonia channel AmtB
分子名称: ACETATE ION, Ammonia channel, IMIDAZOLE, ...
著者Lupo, D, Winkler, F.K.
登録日2008-01-23
公開日2008-03-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Substrate binding, deprotonation, and selectivity at the periplasmic entrance of the Escherichia coli ammonia channel AmtB.
Proc.Natl.Acad.Sci.Usa, 105, 2008
8XLD
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BU of 8xld by Molmil
Structure of the GFP:GFP-nanobody complex from Biortus.
分子名称: 1,2-ETHANEDIOL, Nanobody(Staygold-S2G10)-Nanobody(Staygold-S4F1), ZINC ION, ...
著者Wang, F, Cheng, W, Yuan, Z, Lin, D, Bao, C.
登録日2023-12-25
公開日2024-03-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the GFP:GFP-nanobody complex from Biortus.
To Be Published
3BKC
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BU of 3bkc by Molmil
Crystal structure of anti-amyloid beta FAB WO2 (P21, FormB)
分子名称: SODIUM ION, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa
著者Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W.
登録日2007-12-06
公開日2008-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope.
J.Mol.Biol., 377, 2008
2BDX
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BU of 2bdx by Molmil
X-ray Crystal Structure of dihydromicrocystin-LA bound to Protein Phosphatase-1
分子名称: DIHYDROMICROCYSTIN-LA, MANGANESE (II) ION, Serine/threonine protein phosphatase PP1-gamma catalytic subunit
著者Maynes, J.T, Luu, H.A, Cherney, M.M, Andersen, R.J, Williams, D, Holmes, C.F, James, M.N.
登録日2005-10-21
公開日2006-01-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of Protein Phosphatase-1 Bound to Motuporin and Dihydromicrocystin-LA: Elucidation of the Mechanism of Enzyme Inhibition by Cyanobacterial Toxins.
J.Mol.Biol., 356, 2006
3BM6
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BU of 3bm6 by Molmil
AmpC beta-lactamase in complex with a p.carboxyphenylboronic acid
分子名称: 4-(dihydroxyboranyl)-2-({[4-(phenylsulfonyl)thiophen-2-yl]sulfonyl}amino)benzoic acid, Beta-lactamase
著者Tondi, D.
登録日2007-12-12
公開日2009-02-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural study of phenyl boronic acid derivatives as AmpC beta-lactamase inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010

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