8ASY

SARS-CoV-2 Omicron BA.2.75 RBD in complex with ACE2

Summary for 8ASY

• Entry DOI: 10.2210/pdb8asy/pdb
• Descriptor: Processed angiotensin-converting enzyme 2, Spike protein S1, GLYCEROL, ... (6 entities in total)
• Functional Keywords: sars cov-2, omicron, ba.2.75, ace2, complex, spike, rbd, viral protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 97912.20

Authors

Zhou, D.,Huo, J.,Ren, J.,Stuart, D.I. (deposition date: 2022-08-22, release date: 2023-01-11, Last modification date: 2024-02-07)

• Primary citation: Huo, J.,Dijokaite-Guraliuc, A.,Liu, C.,Zhou, D.,Ginn, H.M.,Das, R.,Supasa, P.,Selvaraj, M.,Nutalai, R.,Tuekprakhon, A.,Duyvesteyn, H.M.E.,Mentzer, A.J.,Skelly, D.,Ritter, T.G.,Amini, A.,Bibi, S.,Adele, S.,Johnson, S.A.,Paterson, N.G.,Williams, M.A.,Hall, D.R.,Plowright, M.,Newman, T.A.H.,Hornsby, H.,de Silva, T.I.,Temperton, N.,Klenerman, P.,Barnes, E.,Dunachie, S.J.,Pollard, A.J.,Lambe, T.,Goulder, P.,Fry, E.E.,Mongkolsapaya, J.,Ren, J.,Stuart, D.I.,Screaton, G.R.; A delicate balance between antibody evasion and ACE2 affinity for Omicron BA.2.75.; Cell Rep, 42:111903-111903, 2022; PubMed: 36586406; DOI: 10.1016/j.celrep.2022.111903

Experimental method

X-RAY DIFFRACTION (2.85 Å)