2C5B

X-ray crystal structure of 5'-fluorodeoxyadenosine synthase from Streptomyces cattleya complexed with 2'deoxy-5'deoxy-fluoroadenosine.

Summary for 2C5B

Entry DOI	10.2210/pdb2c5b/pdb
Related	1RQP 1RQR 2C2W 2C4T 2C4U 2C5H 2CBX 2CC2
Descriptor	5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE, METHIONINE, 5'-FLUORO-2',5'-DIDEOXYADENOSINE, ... (4 entities in total)
Functional Keywords	transferase, fluorinase, 5'-fluorodeoxyadenosine synthase, fla, inhibitor, aza, streptomyces cattleya, sam analogue
Biological source	STREPTOMYCES CATTLEYA
Total number of polymer chains	3
Total formula weight	98411.80
Authors	McEwan, A.R.,Deng, H.,McGlinchey, R.P.,Robinson, D.A.,O'Hagan, D.,Naismith, J.H.,Spencer, J. (deposition date: 2005-10-26, release date: 2007-02-20, Last modification date: 2023-12-13)
Primary citation	Cobb, S.L.,Deng, H.,Mcewan, A.R.,Naismith, J.H.,O'Hagan, D.,Robinson, D.A. Substrate Specificity in Enzymatic Fluorination. The Fluorinase from Streptomyces Cattleya Accepts 2'-Deoxyadenosine Substrates. Org.Biomol.Chem., 4:1458-, 2006 Cited by PubMed: 16604208 DOI: 10.1039/B600574H PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation