5CNO
| Crystal structure of the EGFR kinase domain mutant V924R | 分子名称: | Epidermal growth factor receptor, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Kovacs, E, Das, R, Mirza, A, Jura, N, Barros, T, Kuriyan, J. | 登録日 | 2015-07-17 | 公開日 | 2015-07-29 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Analysis of the Role of the C-Terminal Tail in the Regulation of the Epidermal Growth Factor Receptor. Mol.Cell.Biol., 35, 2015
|
|
6IIC
| CryoEM structure of Mud Crab Dicistrovirus | 分子名称: | VP1 of Mud crab dicistrovirus, VP2 of Mud crab dicistrovirus, VP3 of Mud crab dicistrovirus, ... | 著者 | Zhang, Q, Gao, Y. | 登録日 | 2018-10-04 | 公開日 | 2019-01-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-electron Microscopy Structures of Novel Viruses from Mud CrabScylla paramamosainwith Multiple Infections. J. Virol., 93, 2019
|
|
8IGA
| |
6IZL
| |
8JRR
| Structure of E6AP-E6 complex in Det2 state | 分子名称: | Protein E6, Ubiquitin-protein ligase E3A, ZINC ION | 著者 | Wang, Z, Yu, X. | 登録日 | 2023-06-17 | 公開日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (4.35 Å) | 主引用文献 | Structural insights into the functional mechanism of the ubiquitin ligase E6AP. Nat Commun, 15, 2024
|
|
8JRQ
| Structure of E6AP-E6 complex in Det1 state | 分子名称: | Protein E6, Ubiquitin-protein ligase E3A, ZINC ION | 著者 | Wang, Z, Yu, X. | 登録日 | 2023-06-17 | 公開日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (4.15 Å) | 主引用文献 | Structural insights into the functional mechanism of the ubiquitin ligase E6AP. Nat Commun, 15, 2024
|
|
8JRN
| Structure of E6AP-E6 complex in Att1 state | 分子名称: | Protein E6, Ubiquitin-protein ligase E3A, ZINC ION | 著者 | Wang, Z, Yu, X. | 登録日 | 2023-06-17 | 公開日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural insights into the functional mechanism of the ubiquitin ligase E6AP. Nat Commun, 15, 2024
|
|
8JRP
| Structure of E6AP-E6 complex in Att3 state | 分子名称: | Protein E6, Ubiquitin-protein ligase E3A, ZINC ION | 著者 | Wang, Z, Yu, X. | 登録日 | 2023-06-17 | 公開日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | 主引用文献 | Structural insights into the functional mechanism of the ubiquitin ligase E6AP. Nat Commun, 15, 2024
|
|
8JRO
| Structure of E6AP-E6 complex in Att2 state | 分子名称: | Protein E6, Ubiquitin-protein ligase E3A, ZINC ION | 著者 | Wang, Z, Yu, X. | 登録日 | 2023-06-17 | 公開日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Structural insights into the functional mechanism of the ubiquitin ligase E6AP. Nat Commun, 15, 2024
|
|
7DWN
| Crystal structure of Vibrio fischeri DarR in complex with DNA reveals the transcriptional activation mechanism of LTTR family members | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Predicted DNA-binding transcriptional regulator | 著者 | Wang, W.W, Wu, H, He, J.H, Yu, F. | 登録日 | 2021-01-17 | 公開日 | 2021-07-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Crystal structure details of Vibrio fischeri DarR and mutant DarR-M202I from LTTR family reveals their activation mechanism. Int.J.Biol.Macromol., 183, 2021
|
|
7DWO
| |
7EO8
| Crystal structure of SARS coronavirus main protease in complex with an inhibitor Shikonin | 分子名称: | 2-[(1R)-4-methyl-1-oxidanyl-pent-3-enyl]-5,8-bis(oxidanyl)naphthalene-1,4-dione, 3C-like proteinase | 著者 | Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J. | 登録日 | 2021-04-21 | 公開日 | 2021-10-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2808516 Å) | 主引用文献 | Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus. J.Virol., 96, 2022
|
|
5CNN
| Crystal structure of the EGFR kinase domain mutant I682Q | 分子名称: | Epidermal growth factor receptor, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Kovacs, E, Das, R, Mirza, A, Jura, N, Barros, T, Kuriyan, J. | 登録日 | 2015-07-17 | 公開日 | 2015-07-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Analysis of the Role of the C-Terminal Tail in the Regulation of the Epidermal Growth Factor Receptor. Mol.Cell.Biol., 35, 2015
|
|
7DQZ
| Crystal structure of SARS 3C-like protease in apo form | 分子名称: | 3C-like proteinase | 著者 | Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J. | 登録日 | 2020-12-24 | 公開日 | 2021-09-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus. J.Virol., 96, 2022
|
|
1MFG
| |
1MFL
| |
6AHV
| Crystal structure of human RPP40 | 分子名称: | Ribonuclease P protein subunit p40 | 著者 | Wu, J, Niu, S, Tan, M, Lan, P, Lei, M. | 登録日 | 2018-08-20 | 公開日 | 2018-12-05 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Cryo-EM Structure of the Human Ribonuclease P Holoenzyme. Cell, 175, 2018
|
|
6AHR
| Cryo-EM structure of human Ribonuclease P | 分子名称: | H1 RNA, Ribonuclease P protein subunit p14, Ribonuclease P protein subunit p20, ... | 著者 | Wu, J, Niu, S, Tan, M, Lan, P, Lei, M. | 登録日 | 2018-08-20 | 公開日 | 2018-12-05 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | 主引用文献 | Cryo-EM Structure of the Human Ribonuclease P Holoenzyme. Cell, 175, 2018
|
|
3PV6
| Crystal structure of NKp30 bound to its ligand B7-H6 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig-like domain-containing protein DKFZp686O24166/DKFZp686I21167, ... | 著者 | Li, Y. | 登録日 | 2010-12-06 | 公開日 | 2011-03-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the activating natural killer cell receptor NKp30 bound to its ligand B7-H6 reveals basis for tumor cell recognition in humans to be published
|
|
3PV7
| Crystal structure of NKp30 ligand B7-H6 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig-like domain-containing protein DKFZp686O24166/DKFZp686I21167 | 著者 | Li, Y. | 登録日 | 2010-12-06 | 公開日 | 2011-03-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the activating natural killer cell receptor NKp30 bound to its ligand B7-H6 reveals basis for tumor cell recognition in humans to be published
|
|
7V61
| ACE2 -Targeting Monoclonal Antibody as Potent and Broad-Spectrum Coronavirus Blocker | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3E8, ... | 著者 | Yan, R.H, Zhang, Y.Y, Li, Y.N, Zhou, Q. | 登録日 | 2021-08-18 | 公開日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker. Signal Transduct Target Ther, 6, 2021
|
|
5GSX
| Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 142-2 | 分子名称: | 10-mer peptide from Spike protein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | 著者 | Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F. | 登録日 | 2016-08-17 | 公開日 | 2017-06-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC. J. Immunol., 198, 2017
|
|
5GSV
| Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 142-5 | 分子名称: | 10-mer peptide from Spike protein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | 著者 | Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F. | 登録日 | 2016-08-17 | 公開日 | 2017-04-26 | 実験手法 | X-RAY DIFFRACTION (1.996 Å) | 主引用文献 | Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC. J. Immunol., 198, 2017
|
|
5GSR
| Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide I5A | 分子名称: | 9-mer peptide from Spike protein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | 著者 | Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F. | 登録日 | 2016-08-17 | 公開日 | 2017-04-26 | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | 主引用文献 | Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC. J. Immunol., 198, 2017
|
|
5GR7
| Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 37-1 | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-D alpha chain, ... | 著者 | Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F. | 登録日 | 2016-08-08 | 公開日 | 2017-06-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC. J. Immunol., 198, 2017
|
|