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2QQ2
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BU of 2qq2 by Molmil
Crystal structure of C-terminal domain of Human acyl-CoA thioesterase 7
分子名称: Cytosolic acyl coenzyme A thioester hydrolase
著者Busam, R, Lehtio, L, Arrowsmith, C.H, Berglund, H, Collins, R, Dahlgren, L.G, Herman, M.D, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Tresaugues, L, van den Berg, S, Weigelt, J, Welin, M, Persson, C, Structural Genomics Consortium (SGC)
登録日2007-07-26
公開日2007-08-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Human acyl-CoA thioesterase 7.
To be Published
7VRT
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The unexpanded head structure of phage T4
分子名称: Capsid vertex protein, Major capsid protein
著者Fang, Q, Tang, W, Fokine, A, Mahalingam, M, Shao, Q, Rossmann, M.G, Rao, V.B.
登録日2021-10-24
公開日2022-10-05
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Structures of a large prolate virus capsid in unexpanded and expanded states generate insights into the icosahedral virus assembly.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VS5
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BU of 7vs5 by Molmil
The expanded head structure of phage T4
分子名称: Capsid vertex protein, Major capsid protein, Small outer capsid protein
著者Fang, Q, Tang, W, Fokine, A, Mahalingam, M, Shao, Q, Rossmann, M.G, Rao, V.B.
登録日2021-10-25
公開日2022-10-05
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures of a large prolate virus capsid in unexpanded and expanded states generate insights into the icosahedral virus assembly.
Proc.Natl.Acad.Sci.USA, 119, 2022
2MBX
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BU of 2mbx by Molmil
Structure, dynamics and stability of allergen cod parvalbumin Gad m 1 by solution and high-pressure NMR.
分子名称: CALCIUM ION, Parvalbumin beta
著者Moraes, A.H, Ackerbauer, D, Bublin, M, Ferreira, F, Almeida, F.C.L, Breiteneder, H, Valente, A.
登録日2013-08-07
公開日2014-08-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution and high-pressure NMR studies of the structure, dynamics, and stability of the cross-reactive allergenic cod parvalbumin Gad m 1.
Proteins, 82, 2014
2YID
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BU of 2yid by Molmil
Crystal structure of the SucA domain of Mycobacterium smegmatis alpha- ketoglutarate decarboxylase in complex with the enamine-ThDP intermediate
分子名称: (4E)-4-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-2(3H)-ylidene}-4-hydroxybutanoic acid, 2-OXOGLUTARATE DECARBOXYLASE, CALCIUM ION, ...
著者Wagner, T, Bellinzoni, M, Wehenkel, A.M, O'Hare, H.M, Alzari, P.M.
登録日2011-05-11
公開日2011-06-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Functional Plasticity and Allosteric Regulation of Alpha-Ketoglutarate Decarboxylase in Central Mycobacterial Metabolism.
Chem.Biol., 18, 2011
2YIC
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Crystal structure of the SucA domain of Mycobacterium smegmatis alpha- ketoglutarate decarboxylase (triclinic form)
分子名称: 2-OXOGLUTARATE DECARBOXYLASE, CALCIUM ION, MAGNESIUM ION, ...
著者Wagner, T, Bellinzoni, M, Wehenkel, A.M, O'Hare, H.M, Alzari, P.M.
登録日2011-05-11
公開日2011-06-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Functional Plasticity and Allosteric Regulation of Alpha-Ketoglutarate Decarboxylase in Central Mycobacterial Metabolism.
Chem.Biol., 18, 2011
217D
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BU of 217d by Molmil
CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*)-R(*CP*)-D(*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN
分子名称: DISTAMYCIN A, DNA/RNA (5'-D(*IP*)-R(*CP*)-D(*IP*)-R(*CP*)-D(*IP*CP*IP*C)-3'), MAGNESIUM ION
著者Chen, X, Ramakrishnan, B, Sundaralingam, M.
登録日1995-07-18
公開日1996-01-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of B-form DNA-RNA chimers complexed with distamycin.
Nat.Struct.Biol., 2, 1995
216D
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CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*CP*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN
分子名称: DISTAMYCIN A, DNA/RNA (5'-D(*IP*)-R(*CP*)-D(*IP*CP*IP*CP*IP*C)-3'), MAGNESIUM ION
著者Chen, X, Ramakrishnan, B, Sundaralingam, M.
登録日1995-07-18
公開日1996-01-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal structures of B-form DNA-RNA chimers complexed with distamycin.
Nat.Struct.Biol., 2, 1995
4CQE
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B-Raf Kinase V600E mutant in complex with a diarylthiazole B-Raf Inhibitor
分子名称: N-{4-[2-(1-cyclopropylpiperidin-4-yl)-4-(3-{[(2,5-difluorophenyl)sulfonyl]amino}-2-fluorophenyl)-1,3-thiazol-5-yl]pyridin-2-yl}acetamide, SLC45A3-BRAF FUSION PROTEIN
著者Casale, E, Fasolini, M, Pulici, M, Traquandi, G, Marchionni, C, Modugno, M, Lupi, R, Amboldi, N, Colombo, N, Corti, L, Gasparri, F, Pastori, W, Scolaro, A, Donati, D, Felder, E, Galvani, A, Isacchi, A, Pesenti, E, Ciomei, M.
登録日2014-02-14
公開日2014-12-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Optimization of Diarylthiazole B-Raf Inhibitors: Identification of a Compound Endowed with High Oral Antitumor Activity, Mitigated Herg Inhibition, and Low Paradoxical Effect.
Chemmedchem, 10, 2015
2A36
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BU of 2a36 by Molmil
Solution structure of the N-terminal SH3 domain of DRK
分子名称: Protein E(sev)2B
著者Forman-Kay, J.D, Bezsonova, I, Singer, A, Choy, W.-Y, Tollinger, M.
登録日2005-06-23
公開日2005-12-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Comparison of the Unstable drkN SH3 Domain and a Stable Mutant
Biochemistry, 44, 2005
213D
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CRYSTAL STRUCTURE OF THE A-DNA DECAMER D(CCIGGCCM5CGG) AT 1.6 ANGSTROMS SHOWING THE UNEXPECTED WOBBLE I.M5C BASE PAIR
分子名称: DNA (5'-D(*CP*CP*IP*GP*GP*CP*CP*(5CM)P*GP*G)-3')
著者Ramakrishnan, B, Sundaralingam, M.
登録日1995-06-28
公開日1996-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of the A-DNA decamer d(CCIGGCCm5CGG) at 1.6 A showing the unexpected wobble I.m5C base pair.
Biophys.J., 69, 1995
7Z52
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Human NEXT dimer - focused reconstruction of the single MTR4
分子名称: Exosome RNA helicase MTR4, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(P*UP*UP*UP*UP*U)-3'), ...
著者Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E.
登録日2022-03-07
公開日2022-06-22
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.
Mol.Cell, 82, 2022
7Z4Z
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BU of 7z4z by Molmil
Human NEXT dimer - focused reconstruction of the dimerization module
分子名称: Exosome RNA helicase MTR4, Zinc finger CCHC domain-containing protein 8
著者Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E.
登録日2022-03-06
公開日2022-06-22
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.
Mol.Cell, 82, 2022
7Z4Y
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Human NEXT dimer - overall reconstruction of the core complex
分子名称: Exosome RNA helicase MTR4, Zinc finger CCHC domain-containing protein 8
著者Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E.
登録日2022-03-06
公開日2022-06-22
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.
Mol.Cell, 82, 2022
260D
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CRYSTAL STRUCTURE OF THE SELF-COMPLEMENTARY 5'-PURINE START DECAMER D(GCACGCGTGC) IN THE A-DNA CONFORMATION-PART II
分子名称: DNA (5'-D(*GP*CP*AP*CP*GP*CP*GP*TP*GP*C)-3')
著者Ban, C, Sundaralingam, M.
登録日1996-05-21
公開日1996-06-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the self-complementary 5'-purine start decamer d(GCACGCGTGC) in the A-DNA conformation. II.
Biophys.J., 71, 1996
246D
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STRUCTURE OF THE PURINE-PYRIMIDINE ALTERNATING RNA DOUBLE HELIX, R(GUAUAUA)D(C) , WITH A 3'-TERMINAL DEOXY RESIDUE
分子名称: DNA/RNA (5'-R(*GP*UP*AP*UP*AP*UP*AP*)-D(*C)-3'), SODIUM ION
著者Wahl, M.C, Ban, C, Sekharudu, C, Ramakrishnan, B, Sundaralingam, M.
登録日1996-01-25
公開日1996-08-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the purine-pyrimidine alternating RNA double helix, r(GUAUAUA)d(C), with a 3'-terminal deoxy residue.
Acta Crystallogr.,Sect.D, 52, 1996
2A37
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Solution structure of the T22G mutant of N-terminal SH3 domain of DRK (DRKN SH3 DOMAIN)
分子名称: Protein E(sev)2B
著者Bezsonova, I, Singer, A, Choy, W.-Y, Tollinger, M, Forman-Kay, J.D.
登録日2005-06-23
公開日2005-12-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Comparison of the Unstable drkN SH3 Domain and a Stable Mutant
Biochemistry, 44, 2005
251D
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SINGLE CRYSTAL AND MOLECULAR STRUCTURE OF D(CTCGAG)
分子名称: DNA (5'-D(*CP*TP*CP*GP*AP*G)-3')
著者Wahl, M.C, Rao, S.T, Sundaralingam, M.
登録日1996-03-01
公開日1996-06-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the B-DNA hexamer d(CTCGAG): model for an A-to-B transition.
Biophys.J., 70, 1996
279D
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CRYSTAL STRUCTURE OF THE SELF-COMPLEMENTARY 5'-PURINE START DECAMER D(GCGCGCGCGC) IN THE Z-DNA CONFORMATION-PART I
分子名称: DNA (5'-D(*GP*CP*GP*CP*GP*CP*GP*CP*GP*C)-3'
著者Ban, C, Ramakrishnan, B, Sundaralingam, M.
登録日1996-05-21
公開日1996-06-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the self-complementary 5'-purine start decamer d(GCGCGCGCGC) in the Z-DNA conformation. I.
Biophys.J., 71, 1996
2AWE
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Base-Tetrad Swapping Results in Dimerization of RNA Quadruplexes: Implications for Formation of I-Motif RNA Octaplex
分子名称: 5'-R(*UP*(BGM)P*GP*UP*GP*U)-3', POTASSIUM ION, STRONTIUM ION
著者Pan, B, Shi, K, Sundaralingam, M.
登録日2005-08-31
公開日2006-02-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Base-tetrad swapping results in dimerization of RNA quadruplexes: implications for formation of the i-motif RNA octaplex.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2AZV
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Solution structure of the T22G mutant of N-terminal SH3 domain of DRK (calculated without NOEs)
分子名称: SH2-SH3 adapter protein drk
著者Bezsonova, I, Singer, A.U, Choy, W.-Y, Tollinger, M, Forman-Kay, J.D.
登録日2005-09-12
公開日2005-12-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Comparison of the Unstable drkN SH3 Domain and a Stable Mutant
Biochemistry, 44, 2005
4CXL
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Human insulin analogue (D-ProB8)-insulin
分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN
著者Kosinova, L, Veverka, V, Novotna, P, Collinsova, M, Urbanova, M, Jiracek, J, Moody, N.R, Turkenburg, J.P, Brzozowski, A.M, Zakova, L.
登録日2014-04-07
公開日2014-05-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin.
Biochemistry, 53, 2014
4CXN
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Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form I
分子名称: INSULIN A CHAIN, INSULIN B CHAIN
著者Kosinova, L, Veverka, V, Novotna, P, Collinsova, M, Urbanova, M, Jiracek, J, Moody, N.R, Turkenburg, J.P, Brzozowski, A.M, Zakova, L.
登録日2014-04-07
公開日2014-05-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin.
Biochemistry, 53, 2014
378D
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STRUCTURE OF THE SIDE-BY-SIDE BINDING OF DISTAMYCIN TO DNA
分子名称: DISTAMYCIN A, DNA (5'-D(*GP*TP*AP*TP*AP*TP*AP*C)-3'), SODIUM ION
著者Mitra, S.N, Wahl, M.C, Sundaralingam, M.
登録日1998-01-28
公開日1999-03-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the side-by-side binding of distamycin to d(GTATATAC)2.
Acta Crystallogr.,Sect.D, 55, 1999
326D
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CRYSTAL STRUCTURES OF D(CM5CGGGCCM5CGG)-ORTHOGONAL FORM
分子名称: DNA (5'-D(*CP*(5CM)P*GP*GP*GP*CP*CP*(5CM)P*GP*G)-3'), SPERMINE
著者Tippin, D.B, Sundaralingam, M.
登録日1997-03-17
公開日1997-05-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Nine polymorphic crystal structures of d(CCGGGCCCGG), d(CCGGGCCm5CGG), d(Cm5CGGGCCm5CGG) and d(CCGGGCC(Br)5CGG) in three different conformations: effects of spermine binding and methylation on the bending and condensation of A-DNA.
J.Mol.Biol., 267, 1997

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