2QQ2

Crystal structure of C-terminal domain of Human acyl-CoA thioesterase 7

Summary for 2QQ2

DescriptorCytosolic acyl coenzyme A thioester hydrolase (1 entity in total)
Functional Keywordsacot7, c-terminal domain, thioesterase, structural genomics, structural genomics consortium, sgc, hydrolase, mitochondrion, serine esterase
Biological sourceHomo sapiens (human)
Cellular locationIsoform 4: Cytoplasm. Isoform 6: Cytoplasm. Isoform 1: Mitochondrion. Isoform 5: Mitochondrion O00154
Total number of polymer chains12
Total molecular weight256671.05
Authors
Primary citation
Busam, R.,Lehtio, L.,Arrowsmith, C.H.,Berglund, H.,Collins, R.,Dahlgren, L.G.,Herman, M.D.,Edwards, A.,Flodin, S.,Flores, A.,Greslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg-Schiavone, L.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotenyova, T.,Moche, M.,Nordlund, P.,Nyman, T.,Sagemark, J.,Stenmark, P.,Sundstrom, M.,Thorsell, A.G.,Tresaugues, L.,van den Berg, S.,Weigelt, J.,Welin, M.,Persson, C.
Human acyl-CoA thioesterase 7.
To be Published,
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.228100.4%4.5%2.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2qq2
no rotation
Molmil generated image of 2qq2
rotated about x axis by 90°
Molmil generated image of 2qq2
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 2qq2
no rotation
Molmil generated image of 2qq2
rotated about x axis by 90°
Molmil generated image of 2qq2
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2qq2.pdb1.gz [144.62 KB])
Coordinate files for Biological unit (2qq2.pdb2.gz [141.36 KB])