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7VYP
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The structure of GdmN complex with the natural tetrahedral intermediate, carbamoylated derivative, and AMP
分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, FE (III) ION, ...
著者Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L.
登録日2021-11-15
公開日2022-11-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.
Nat Commun, 13, 2022
7VZY
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The structure of GdmN complex with AMP and 20-O-methyl-19-chloroproansamitocin
分子名称: (5~{S},6~{E},8~{S},9~{S},12~{R},15~{E})-21-chloranyl-12,20-dimethoxy-6,8,16-trimethyl-5,9-bis(oxidanyl)-2-azabicyclo[16.3.1]docosa-1(21),6,15,18(22),19-pentaene-3,11-dione, 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, ...
著者Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L.
登録日2021-11-17
公開日2022-11-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.
Nat Commun, 13, 2022
7VYJ
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The structure of GdmN in complex with carbamoyl adenylate intermediate
分子名称: 1,2-ETHANEDIOL, 5'-O-[(S)-(carbamoyloxy)(hydroxy)phosphoryl]adenosine, DI(HYDROXYETHYL)ETHER, ...
著者Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L.
登録日2021-11-14
公開日2022-11-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.
Nat Commun, 13, 2022
7VYO
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The structure of GdmN
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L.
登録日2021-11-14
公開日2022-11-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.
Nat Commun, 13, 2022
7VZZ
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The structure of GdmN in complex with the natural tetrahedral intermediate, carbamoyl adenylate, and 20-O-methyl-19-chloroproansamitocin
分子名称: (5~{S},6~{E},8~{S},9~{S},12~{R},15~{E})-21-chloranyl-12,20-dimethoxy-6,8,16-trimethyl-5,9-bis(oxidanyl)-2-azabicyclo[16.3.1]docosa-1(21),6,15,18(22),19-pentaene-3,11-dione, 1,2-ETHANEDIOL, 5'-O-[(S)-(carbamoyloxy)(hydroxy)phosphoryl]adenosine, ...
著者Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L.
登録日2021-11-17
公開日2022-11-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.
Nat Commun, 13, 2022
7Y54
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Crystal structure of sDscam Ig1 domain, isoform alpha1
分子名称: Down Syndrome Cell Adhesion Molecules
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-16
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.787 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y6O
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Crystal structure of sDscam Ig1-3 domains, isoform alpha25
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Down Syndrome Cell Adhesion Molecules
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-21
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.102 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y9A
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Crystal structure of sDscam Ig1-2 domains, isoform beta2v6
分子名称: Down Syndrome Cell Adhesion Molecules, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-3)][beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-24
公開日2023-05-24
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y4X
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Crystal structure of sDscam Ig1 domain, isoform alpha7
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Down syndrome cell adhesion molecule
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-16
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.952 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y5J
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Crystal structure of sDscam Ig1 domain, isoform alpha1v7
分子名称: Down Syndrome Cell Adhesion Molecules
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-17
公開日2023-05-24
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y5R
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BU of 7y5r by Molmil
Crystal structure of sDscam FNIII2 domain, isoform alpha7
分子名称: Down Syndrome Cell Adhesion Molecules, GLYCEROL
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-17
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.562 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y73
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Crystal structure of sDscam Ig1 domain, isoform beta3v7
分子名称: Down Syndrome Cell Adhesion Molecules, GLYCEROL
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-21
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y6E
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Crystal structure of sDscam FNIII23 domains, isoform Beta2v6
分子名称: Dscam
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-20
公開日2023-05-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.034 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y8S
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Crystal structure of sDscam FNIII1-3 domains, isoform beta2v6
分子名称: Dscam, SODIUM ION
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-24
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.696 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y8I
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BU of 7y8i by Molmil
Crystal structure of sDscam FNIII3 domain, isoform alpha7
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Dscam, ...
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-24
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y8H
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BU of 7y8h by Molmil
Crystal structure of sDscam FNIII1 domain, isoform alpha7
分子名称: Down Syndrome Cell Adhesion Molecules, SULFATE ION
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-23
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y95
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Crystal structure of sDscam Ig1 domain, isoform beta6v2
分子名称: Dscam, GLYCEROL, SODIUM ION
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-24
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7VX0
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BU of 7vx0 by Molmil
The structure of GdmN complex with ATP
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, FE (III) ION, ...
著者Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L.
登録日2021-11-12
公開日2022-11-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.
Nat Commun, 13, 2022
4X9J
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EGR-1 with Doubly Methylated DNA
分子名称: DNA (5'-D(*AP*GP*(5CM)P*GP*TP*GP*GP*GP*(5CM)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*(5CM)P*GP*C)-3'), Early growth response protein 1, ...
著者White, M.A, Zandarashvili, L, Iwahara, J.
登録日2014-12-11
公開日2015-05-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.412 Å)
主引用文献Structural impact of complete CpG methylation within target DNA on specific complex formation of the inducible transcription factor Egr-1.
Febs Lett., 589, 2015
6WOK
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Crystal structure of estrogen receptor alpha in complex with receptor degrader 6
分子名称: (1R,3R)-1-(2,6-difluoro-4-{2-[3-(fluoromethyl)azetidin-1-yl]ethoxy}phenyl)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-beta-carboline, (2S)-3-(3-hydroxyphenyl)-2-(4-iodophenyl)-4-methyl-2H-1-benzopyran-6-ol, Estrogen receptor
著者Kiefer, J.R, Vinogradova, M, Liang, J, Zhang, B, Wang, X, Labadie, S.
登録日2020-04-24
公開日2020-07-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.309 Å)
主引用文献Discovery of GNE-149 as a Full Antagonist and Efficient Degrader of Estrogen Receptor alpha for ER+ Breast Cancer.
Acs Med.Chem.Lett., 11, 2020
4XIC
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ANTPHD WITH 15BP di-thioate modified DNA DUPLEX
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*(C2S)P*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ...
著者White, M.A, Zandarashvili, L, Iwahara, J.
登録日2015-01-06
公開日2015-11-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Entropic Enhancement of Protein-DNA Affinity by Oxygen-to-Sulfur Substitution in DNA Phosphate.
Biophys.J., 109, 2015
2GEB
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BU of 2geb by Molmil
Crystal structure of the Thermoanaerobacter tengcongensis hypoxanthine-guanine phosphoribosyltransferase L160I mutant: insights into the inhibitor design
分子名称: CALCIUM ION, Hypoxanthine-guanine phosphoribosyltransferase
著者Chen, Q, Luo, M.
登録日2006-03-19
公開日2007-04-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of Thermoanaerobacter tengcongensis hypoxanthine-guanine phosphoribosyl transferase L160I mutant--insights into inhibitor design.
Febs J., 274, 2007
7RX2
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BU of 7rx2 by Molmil
afTMEM16 in C22 lipid nanodiscs with MSP1E3 scaffold protein in the presnece of Ca2+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, afTMEM16 lipid scramblase
著者Falzone, M.E, Accardi, A.
登録日2021-08-21
公開日2022-05-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RWJ
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afTMEM16 in C22 lipid nanodiscs with MSP2N2 scaffold protein in the presnece of Ca2+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Plasma membrane channel protein (Aqy1), ...
著者Falzone, M.E, Accardi, A.
登録日2021-08-20
公開日2022-05-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RXB
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afTMEM16 lipid scramblase in C18 lipid nanodiscs in the absence of Ca2+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, afTMEM16 lipid scramblase
著者Feng, Z, Accardi, A.
登録日2021-08-22
公開日2022-05-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022

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件を2024-10-16に公開中

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