5ZNS
 
 | | Insect chitin deacetylase | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... | | 著者 | Liu, L, Zhou, Y, Yang, Q. | | 登録日 | 2018-04-10 | | 公開日 | 2019-02-20 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.396 Å) | | 主引用文献 | Structural and biochemical insights into the catalytic mechanisms of two insect chitin deacetylases of the carbohydrate esterase 4 family.
J. Biol. Chem., 294, 2019
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3F7O
 | | Crystal structure of Cuticle-Degrading Protease from Paecilomyces lilacinus (PL646) | | 分子名称: | (MSU)(ALA)(ALA)(PRO)(VAL), CALCIUM ION, Serine protease | | 著者 | Liang, L, Lou, Z, Meng, Z, Rao, Z, Zhang, K. | | 登録日 | 2008-11-10 | | 公開日 | 2009-11-17 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The crystal structures of two cuticle-degrading proteases from nematophagous fungi and their contribution to infection against nematodes.
Faseb J., 24, 2010
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7JM5
 | | Crystal structure of KDM4B in complex with QC6352 | | 分子名称: | 3-[({(1R)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahydronaphthalen-1-yl}methyl)amino]pyridine-4-carboxylic acid, Lysine-specific demethylase 4B, NICKEL (II) ION, ... | | 著者 | White, S.W, Yun, M. | | 登録日 | 2020-07-31 | | 公開日 | 2022-02-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Targeting KDM4 for treating PAX3-FOXO1-driven alveolar rhabdomyosarcoma.
Sci Transl Med, 14, 2022
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7ZMZ
 | | Engineered Interleukin 2 bound to CD25 receptor | | 分子名称: | Interleukin-2, Interleukin-2 receptor subunit alpha | | 著者 | Fyfe, P.K, Moraga, I, Gaggero, S, Mitra, S. | | 登録日 | 2022-04-20 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein.
Sci Immunol, 7, 2022
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3F7M
 | | Crystal structure of apo Cuticle-Degrading Protease (ver112) from Verticillium psalliotae | | 分子名称: | Alkaline serine protease ver112 | | 著者 | Liang, L, Lou, Z, Ye, F, Meng, Z, Rao, Z, Zhang, K. | | 登録日 | 2008-11-09 | | 公開日 | 2009-11-17 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The crystal structures of two cuticle-degrading proteases from nematophagous fungi and their contribution to infection against nematodes.
Faseb J., 24, 2010
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4YZD
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8K98
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8K9A
 | | Cryo-EM structure of DSR2-DSAD1 state 2 | | 分子名称: | SIR2-like domain-containing protein, SPbeta prophage-derived uncharacterized protein YotI | | 著者 | Zhang, H, Li, Z, Li, X.Z. | | 登録日 | 2023-07-31 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Insights into the modulation of bacterial NADase activity by phage proteins.
Nat Commun, 15, 2024
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8HNV
 | | CryoEM structure of HpaCas9-sgRNA-dsDNA in the presence of AcrIIC4 | | 分子名称: | CRISPR-associated endonuclease Cas9, anti-CRISPR protein AcrIIC4, non-target strand, ... | | 著者 | Sun, W, Cheng, Z, Wang, J, Yang, X, Wang, Y. | | 登録日 | 2022-12-08 | | 公開日 | 2023-07-19 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
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3B5R
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3B66
 | | Crystal structure of the androgen receptor ligand binding domain in complex with SARM S-21 | | 分子名称: | 4-{[(1R,2S)-1,2-dihydroxy-2-methyl-3-(4-nitrophenoxy)propyl]amino}-2-(trifluoromethyl)benzonitrile, Androgen receptor | | 著者 | Bohl, C.E, Miller, D.D, Dalton, J.T. | | 登録日 | 2007-10-27 | | 公開日 | 2008-09-09 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Effect of B-ring substitution pattern on binding mode of propionamide selective androgen receptor modulators
Bioorg.Med.Chem.Lett., 18, 2008
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6X7U
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3B67
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3B65
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6X7V
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6YXE
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3B68
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5ULA
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6LHU
 | | High resolution structure of FANCA C-terminal domain (CTD) | | 分子名称: | Fanconi anemia complementation group A | | 著者 | Jeong, E, Lee, S, Shin, J, Kim, Y, Kim, J, Scharer, O, Kim, Y, Kim, H, Cho, Y. | | 登録日 | 2019-12-10 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex.
Nucleic Acids Res., 48, 2020
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6LHW
 | | Structure of N-terminal and C-terminal domains of FANCA | | 分子名称: | Fanconi anemia complementation group A | | 著者 | Jeong, E, Lee, S, Shin, J, Kim, Y, Kim, J, Scharer, O, Kim, Y, Kim, H, Cho, Y. | | 登録日 | 2019-12-10 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.84 Å) | | 主引用文献 | Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex.
Nucleic Acids Res., 48, 2020
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8HNW
 | | Crystal structure of HpaCas9-sgRNA surveillance complex bound to double-stranded DNA | | 分子名称: | CRISPR-associated endonuclease Cas9, Non-target strand, Target strand, ... | | 著者 | Sun, W, Cheng, Z, Wang, Y. | | 登録日 | 2022-12-08 | | 公開日 | 2023-07-19 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | | 主引用文献 | AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8HNT
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7YPE
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7YPF
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4I6L
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