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1QNK
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BU of 1qnk by Molmil
TRUNCATED HUMAN GROB[5-73], NMR, 20 STRUCTURES
分子名称: C-X-C motif chemokine 2
著者Qian, Y.Q, Johanson, K, McDevitt, P.
登録日1999-10-18
公開日2000-02-04
最終更新日2018-06-13
実験手法SOLUTION NMR
主引用文献Nuclear magnetic resonance solution structure of truncated human GRObeta [5-73] and its structural comparison with CXC chemokine family members GROalpha and IL-8.
J. Mol. Biol., 294, 1999
4OXR
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BU of 4oxr by Molmil
Structure of Staphylococcus pseudintermedius metal-binding protein SitA in complex with Manganese
分子名称: MANGANESE (II) ION, Manganese ABC transporter, periplasmic-binding protein SitA
著者Abate, F, Malito, E, Bottomley, M.
登録日2014-02-06
公開日2014-10-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Apo, Zn2+-bound and Mn2+-bound structures reveal ligand-binding properties of SitA from the pathogen Staphylococcus pseudintermedius.
Biosci.Rep., 34, 2014
2IUN
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BU of 2iun by Molmil
Structure of the C-terminal head domain of the avian adenovirus CELO long fibre (P21 crystal form)
分子名称: AVIAN ADENOVIRUS CELO LONG FIBRE, CALCIUM ION
著者Guardado-Calvo, P, Llamas-Saiz, A.L, Fox, G.C, van Raaij, M.J.
登録日2006-06-06
公開日2007-06-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the C-terminal head domain of the fowl adenovirus type 1 long fiber.
J. Gen. Virol., 88, 2007
3GIN
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BU of 3gin by Molmil
Crystal structure of E454K-CBD1
分子名称: CALCIUM ION, Sodium/calcium exchanger 1
著者Chaptal, V, Mercado-Besserer, G, Abramson, J.
登録日2009-03-05
公開日2009-04-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and functional analysis of a Ca2+ sensor mutant of the na+/ca2+ exchanger
J.Biol.Chem., 284, 2009
4OXQ
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BU of 4oxq by Molmil
Structure of Staphylococcus pseudintermedius metal-binding protein SitA in complex with Zinc
分子名称: Manganese ABC transporter, periplasmic-binding protein SitA, ZINC ION
著者Abate, F, Malito, E, Bottomley, M.
登録日2014-02-06
公開日2014-10-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Apo, Zn2+-bound and Mn2+-bound structures reveal ligand-binding properties of SitA from the pathogen Staphylococcus pseudintermedius.
Biosci.Rep., 34, 2014
8C6N
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BU of 8c6n by Molmil
Human protein kinase CK2 alpha in complex with CK2-TN03
分子名称: (2~{Z},5~{Z})-5-[(4-methoxy-3-oxidanyl-phenyl)methylidene]-2-phenylimino-1,3-thiazolidin-4-one, Casein kinase II subunit alpha, SULFATE ION
著者Dalle Vedove, A, Cazzanelli, G, Lolli, G.
登録日2023-01-12
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Switching off CK2-mediated activation of survivin offers new therapeutic opportunities in neuroblastoma
to be published
8C6M
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BU of 8c6m by Molmil
Human protein kinase CK2 alpha in complex with CK2-TN02
分子名称: (5~{Z})-5-[(3-methoxy-4-oxidanyl-phenyl)methylidene]-1,3-thiazolidine-2,4-dione, Casein kinase II subunit alpha, SULFATE ION
著者Dalle Vedove, A, Cazzanelli, G, Lolli, G.
登録日2023-01-12
公開日2024-04-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Switching off CK2-mediated activation of survivin offers new therapeutic opportunities in neuroblastoma
to be published
8C6L
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BU of 8c6l by Molmil
Human protein kinase CK2 alpha in complex with CK2-TN01
分子名称: 1,2-ETHANEDIOL, 5-azanyl-3-[(~{Z})-1-cyano-2-(3-methoxy-4-oxidanyl-phenyl)ethenyl]-3~{H}-pyrazole-4-carbonitrile, Casein kinase II subunit alpha, ...
著者Dalle Vedove, A, Cazzanelli, G, Lolli, G.
登録日2023-01-12
公開日2024-04-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Switching off CK2-mediated activation of survivin offers new therapeutic opportunities in neuroblastoma
to be published
3CS1
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BU of 3cs1 by Molmil
Flagellar Calcium-binding Protein (FCaBP) from T. cruzi
分子名称: Flagellar calcium-binding protein
著者Ames, J.B, Ladner, J.E, Wingard, J.N, Robinson, H, Fisher, A.
登録日2008-04-08
公開日2008-06-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights into Membrane Targeting by the Flagellar Calcium-binding Protein (FCaBP), a Myristoylated and Palmitoylated Calcium Sensor in Trypanosoma cruzi.
J.Biol.Chem., 283, 2008
3CXK
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BU of 3cxk by Molmil
1.7 A Crystal structure of methionine-R-sulfoxide reductase from Burkholderia pseudomallei: crystallization in a microfluidic crystal card.
分子名称: ACETATE ION, Methionine-R-sulfoxide reductase, ZINC ION
著者Lovell, S, Gerdts, C, Staker, B, Craigen, D, Stewart, L, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2008-04-24
公開日2008-05-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The plug-based nanovolume Microcapillary Protein Crystallization System (MPCS).
Acta Crystallogr.,Sect.D, 64, 2008
1MEG
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BU of 1meg by Molmil
CRYSTAL STRUCTURE OF A CARICAIN D158E MUTANT IN COMPLEX WITH E-64
分子名称: CARICAIN, ETHANOL, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE
著者Katerelos, N.A.
登録日1996-05-04
公開日1997-01-11
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a caricain D158E mutant in complex with E-64.
FEBS Lett., 392, 1996
6CR2
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BU of 6cr2 by Molmil
Crystal structure of sterol 14-alpha demethylase (CYP51B) from Aspergillus fumigatus in complex with the VNI derivative N-(1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl)-4-(5-(2-fluoro-4-(2,2,2-trifluoroethoxy)phenyl)-1,3,4-oxadiazol-2-yl)benzamide
分子名称: 14-alpha sterol demethylase Cyp51B, N-[(1R)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl]-4-{5-[2-fluoro-4-(2,2,2-trifluoroethoxy)phenyl]-1,3,4-oxadiazol-2-yl}benzamide, PROTOPORPHYRIN IX CONTAINING FE
著者Friggeri, L, Hargrove, T.Y, Wawrzak, Z, Lepesheva, G.I.
登録日2018-03-16
公開日2018-06-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Sterol 14 alpha-Demethylase Structure-Based Design of VNI (( R)- N-(1-(2,4-Dichlorophenyl)-2-(1 H-imidazol-1-yl)ethyl)-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide)) Derivatives To Target Fungal Infections: Synthesis, Biological Evaluation, and Crystallographic Analysis.
J. Med. Chem., 61, 2018
4RWR
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BU of 4rwr by Molmil
2.1 Angstrom Crystal Structure of Stage II Sporulation Protein D from Bacillus anthracis
分子名称: Stage II sporulation protein D
著者Minasov, G, Wawrzak, Z, Nocadello, S, Shuvalova, L, Dubrovska, I, Flores, K, Bagnoli, F, Falugi, F, Bottomley, M, Grandi, G, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-12-05
公開日2014-12-17
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of the SpoIID Lytic Transglycosylases Essential for Bacterial Sporulation.
J.Biol.Chem., 291, 2016
5DWU
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BU of 5dwu by Molmil
Beta common receptor in complex with a Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit beta, Fab - Heavy Chain, ...
著者Dhagat, U, Parker, M.W.
登録日2015-09-23
公開日2015-12-30
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.97 Å)
主引用文献CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common beta chain of the IL-3, GM-CSF and IL-5 receptors.
Mabs, 8, 2016
7JSE
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BU of 7jse by Molmil
Adeno-Associated Virus Origin Binding Domain in complex with ssDNA
分子名称: DNA (5'-D(*TP*TP*TP*T)-3'), Protein Rep68
著者Escalante, C.R.
登録日2020-08-14
公開日2020-12-09
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states.
Nucleic Acids Res., 48, 2020
6FBV
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BU of 6fbv by Molmil
Single particle cryo em structure of Mycobacterium tuberculosis RNA polymerase in complex with Fidaxomicin
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Das, K, Lin, W, Ebright, E.
登録日2017-12-19
公開日2018-02-28
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3).
Mol. Cell, 70, 2018
7JSH
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BU of 7jsh by Molmil
Adeno-Associated Virus 2 Rep68 HD Heptamer-ssAAVS1 with ATPgS
分子名称: DNA (5'-D(P*CP*GP*CP*TP*CP*GP*CP*TP*CP*GP*CP*TP*CP*GP*C)-3'), Protein Rep68
著者Escalante, C.R.
登録日2020-08-14
公開日2020-12-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states.
Nucleic Acids Res., 48, 2020
7JSG
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BU of 7jsg by Molmil
Adeno-Associated Virus 2 Rep68 HD-Heptamer-ssDNA with ATPgS
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Protein Rep68
著者Escalante, C.R.
登録日2020-08-14
公開日2020-12-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states.
Nucleic Acids Res., 48, 2020
2BSP
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BU of 2bsp by Molmil
BACILLUS SUBTILIS PECTATE LYASE R279K MUTANT
分子名称: CALCIUM ION, PROTEIN (PECTATE LYASE)
著者Pickersgill, R.
登録日1998-07-31
公開日1998-08-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Conserved Arginine Proximal to the Essential Calcium of Bacillus Subtilis Pectate Lyase Stabilizes the Transition State
To be Published
7JSI
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BU of 7jsi by Molmil
Adeno-Associated Virus 2 Rep68 HD Hexamer-ssDNA with ATPgS
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*T)-3'), Protein Rep68
著者Escalante, C.R.
登録日2020-08-14
公開日2020-12-16
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (5.01 Å)
主引用文献The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states.
Nucleic Acids Res., 48, 2020
7JSF
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BU of 7jsf by Molmil
Adeno-Associated Virus Helicase domain Heptamer with ssDNA
分子名称: DNA (5'-D(P*TP*TP*TP*T)-3'), Protein Rep68
著者Escalante, C.R.
登録日2020-08-14
公開日2020-12-16
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states.
Nucleic Acids Res., 48, 2020
5EML
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BU of 5eml by Molmil
Crystal structure of PRMT5:MEP50 with Compound 10 and SAM
分子名称: GLYCEROL, Methylosome protein 50, Protein arginine N-methyltransferase 5, ...
著者Boriack-Sjodin, P.A, Jin, L.
登録日2015-11-06
公開日2016-02-24
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666.
ACS Med Chem Lett, 7, 2016
5EMM
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Crystal structure of PRMT5:MEP50 with Compound 15 and sinefungin
分子名称: GLYCEROL, Methylosome protein 50, Protein arginine N-methyltransferase 5, ...
著者Boriack-Sjodin, P.A, Jin, L.
登録日2015-11-06
公開日2016-02-24
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666.
ACS Med Chem Lett, 7, 2016
5EMJ
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Crystal structure of PRMT5:MEP50 with Compound 8 and sinefungin
分子名称: (2~{S})-1-(3,4-dihydro-1~{H}-isoquinolin-2-yl)-3-[[4-(3-methylbenzimidazol-5-yl)pyridin-2-yl]amino]propan-2-ol, GLYCEROL, Methylosome protein 50, ...
著者Boriack-Sjodin, P.A, Jin, L.
登録日2015-11-06
公開日2016-02-24
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.273 Å)
主引用文献Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666.
ACS Med Chem Lett, 7, 2016
5EMK
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Crystal structure of PRMT5:MEP50 with Compound 9 and sinefungin
分子名称: GLYCEROL, Methylosome protein 50, Protein arginine N-methyltransferase 5, ...
著者Boriack-Sjodin, P.A, Jin, L.
登録日2015-11-06
公開日2016-02-24
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666.
ACS Med Chem Lett, 7, 2016

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