8C6N

Human protein kinase CK2 alpha in complex with CK2-TN03

Summary for 8C6N

• Entry DOI: 10.2210/pdb8c6n/pdb
• Related: 8C6L 8C6M
• Descriptor: Casein kinase II subunit alpha, (2~{Z},5~{Z})-5-[(4-methoxy-3-oxidanyl-phenyl)methylidene]-2-phenylimino-1,3-thiazolidin-4-one, SULFATE ION, ... (4 entities in total)
• Functional Keywords: kinase domain, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 40768.38

Authors

Dalle Vedove, A.,Cazzanelli, G.,Lolli, G. (deposition date: 2023-01-12, release date: 2024-04-24)

• Primary citation: Cazzanelli, G.,Dalle Vedove, A.,Broso, F.,Burigotto, M.,Aiello, G.,Ruzzene, M.,Tiberi, L.,Fava, L.,Quattrone, A.,Lolli, G.; Switching off CK2-mediated activation of survivin offers new therapeutic opportunities in neuroblastoma; to be published,

Experimental method

X-RAY DIFFRACTION (2.05 Å)