8SGT

Cryo-EM structure of human NCX1 in Ca2+ bound, activated state (group II in the presence of 0.5 mM Ca2+)

Summary for 8SGT

• Entry DOI: 10.2210/pdb8sgt/pdb
• EMDB information: 40460 40467
• Descriptor: Sodium/calcium exchanger 1, Fab light chain, Fab heavy chain, ... (4 entities in total)
• Functional Keywords: na/ca exchanger, sodium calcium exchanger, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 157597.22

Authors

Xue, J.,Jiang, Y. (deposition date: 2023-04-13, release date: 2023-10-11, Last modification date: 2023-11-01)

• Primary citation: Xue, J.,Zeng, W.,Han, Y.,John, S.,Ottolia, M.,Jiang, Y.; Structural mechanisms of the human cardiac sodium-calcium exchanger NCX1.; Nat Commun, 14:6181-6181, 2023; PubMed: 37794011; DOI: 10.1038/s41467-023-41885-4

Experimental method

ELECTRON MICROSCOPY (3.6 Å)