8SGT
Cryo-EM structure of human NCX1 in Ca2+ bound, activated state (group II in the presence of 0.5 mM Ca2+)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium/calcium exchanger 1 | polymer | 982 | 109181.1 | 1 | UniProt (P32418) Pfam (PF01699) Pfam (PF16494) Pfam (PF03160) | Homo sapiens (human) | Na(+)/Ca(2+)-exchange protein 1,Solute carrier family 8 member 1 |
| 2 | B (L) | Fab light chain | polymer | 202 | 21740.1 | 1 | Mus musculus | ||
| 3 | C (H) | Fab heavy chain | polymer | 249 | 26435.6 | 1 | Mus musculus | ||
| 4 | D, E, F, G, H... (A) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) |
Sequence modifications
A: -34 - 938 (UniProt: P32418)
| PDB | External Database | Details |
|---|---|---|
| - | Gly 376 | deletion |
| - | Asn 377 | deletion |
| - | Ile 378 | deletion |
| - | Leu 379 | deletion |
| - | Lys 380 | deletion |
| - | Arg 381 | deletion |
| - | His 382 | deletion |
| - | Ala 383 | deletion |
| - | Ala 384 | deletion |
| - | Asp 385 | deletion |
| - | Gln 386 | deletion |
| - | Ala 387 | deletion |
| - | Arg 388 | deletion |
| - | Lys 389 | deletion |
| - | Ala 390 | deletion |
| - | Val 391 | deletion |
| - | Ser 392 | deletion |
| - | Met 393 | deletion |
| - | His 394 | deletion |
| - | Glu 395 | deletion |
| - | Val 396 | deletion |
| - | Asn 397 | deletion |
| - | Thr 398 | deletion |
| - | Glu 399 | deletion |
| - | Val 400 | deletion |
| Ala 939 | - | expression tag |
| Ala 940 | - | expression tag |
| Ala 941 | - | expression tag |
| Gly 942 | - | expression tag |
| Gly 943 | - | expression tag |
| Ser 944 | - | expression tag |
| Trp 945 | - | expression tag |
| Ser 946 | - | expression tag |
| His 947 | - | expression tag |
| Pro 948 | - | expression tag |
| Gln 949 | - | expression tag |
| Phe 950 | - | expression tag |
| Glu 951 | - | expression tag |
| Lys 952 | - | expression tag |
| Gly 953 | - | expression tag |
| Gly 954 | - | expression tag |
| Gly 955 | - | expression tag |
| Ser 956 | - | expression tag |
| Gly 957 | - | expression tag |
| Gly 958 | - | expression tag |
| Gly 959 | - | expression tag |
| Ser 960 | - | expression tag |
| Gly 961 | - | expression tag |
| Gly 962 | - | expression tag |
| Ser 963 | - | expression tag |
| Ala 964 | - | expression tag |
| Trp 965 | - | expression tag |
| Ser 966 | - | expression tag |
| His 967 | - | expression tag |
| Pro 968 | - | expression tag |
| Gln 969 | - | expression tag |
| Phe 970 | - | expression tag |
| Glu 971 | - | expression tag |
| Lys 972 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 157356.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 240.5 | |
| All* | Total formula weight | 157597.2 |
