6ASG

Crystal structure of Thermus thermophilus RNA polymerase core enzyme

Summary for 6ASG

• Entry DOI: 10.2210/pdb6asg/pdb
• Descriptor: DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', DNA-directed RNA polymerase subunit alpha, ... (6 entities in total)
• Functional Keywords: thermus thermophilus, rna polymerase core enzyme, transcription
• Biological source: Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579); More
• Total number of polymer chains: 5
• Total formula weight: 378234.70

Authors

Liu, Y.,Lin, W.,Ying, R.,Ebright, R.H. (deposition date: 2017-08-24, release date: 2018-04-11, Last modification date: 2023-10-04)

• Primary citation: Lin, W.,Das, K.,Degen, D.,Mazumder, A.,Duchi, D.,Wang, D.,Ebright, Y.W.,Ebright, R.Y.,Sineva, E.,Gigliotti, M.,Srivastava, A.,Mandal, S.,Jiang, Y.,Liu, Y.,Yin, R.,Zhang, Z.,Eng, E.T.,Thomas, D.,Donadio, S.,Zhang, H.,Zhang, C.,Kapanidis, A.N.,Ebright, R.H.; Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3).; Mol. Cell, 70:60-71.e15, 2018; PubMed: 29606590; DOI: 10.1016/j.molcel.2018.02.026

Experimental method

X-RAY DIFFRACTION (3.8 Å)