8C6M

Human protein kinase CK2 alpha in complex with CK2-TN02

Summary for 8C6M

• Entry DOI: 10.2210/pdb8c6m/pdb
• Related: 8C6L
• Descriptor: Casein kinase II subunit alpha, (5~{Z})-5-[(3-methoxy-4-oxidanyl-phenyl)methylidene]-1,3-thiazolidine-2,4-dione, SULFATE ION, ... (4 entities in total)
• Functional Keywords: kinase domain, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 40693.27

Authors

Dalle Vedove, A.,Cazzanelli, G.,Lolli, G. (deposition date: 2023-01-12, release date: 2024-04-24)

• Primary citation: Cazzanelli, G.,Dalle Vedove, A.,Broso, F.,Burigotto, M.,Aiello, G.,Ruzzene, M.,Tiberi, L.,Fava, L.,Quattrone, A.,Lolli, G.; Switching off CK2-mediated activation of survivin offers new therapeutic opportunities in neuroblastoma; to be published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)