6R5M
 
 | | Crystal structure of toxin MT9 from mamba venom | | 分子名称: | ACETYL GROUP, Dendroaspis polylepis MT9, GLYCEROL, ... | | 著者 | Stura, E.A, Tepshi, L, Ciolek, J, Triquigneaux, M, Zoukimian, C, De Waard, M, Beroud, R, Servent, D, Gilles, N, Legrand, P, Ciccone, L. | | 登録日 | 2019-03-25 | | 公開日 | 2020-02-12 | | 最終更新日 | 2022-05-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | MT9, a natural peptide from black mamba venom antagonizes the muscarinic type 2 receptor and reverses the M2R-agonist-induced relaxation in rat and human arteries
Biomed Pharmacother, 150, 2022
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2BJI
 | | High Resolution Structure of myo-Inositol Monophosphatase, The Target of Lithium Therapy | | 分子名称: | INOSITOL-1(OR 4)-MONOPHOSPHATASE, MAGNESIUM ION | | 著者 | Gill, R, Mohammed, F, Badyal, R, Coates, L, Erskine, P, Thompson, D, Cooper, J, Gore, M, Wood, S. | | 登録日 | 2005-02-03 | | 公開日 | 2005-02-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | | 主引用文献 | High-resolution structure of myo-inositol monophosphatase, the putative target of lithium therapy.
Acta Crystallogr. D Biol. Crystallogr., 61, 2005
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1K6Q
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6GP0
 | | Structure of mEos4b in the red fluorescent state | | 分子名称: | Green to red photoconvertible GFP-like protein EosFP | | 著者 | De Zitter, E, Adam, V, Byrdin, M, Van Meervelt, L, Dedecker, P, Bourgeois, D. | | 登録日 | 2018-06-04 | | 公開日 | 2019-05-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Mechanistic investigation of mEos4b reveals a strategy to reduce track interruptions in sptPALM.
Nat.Methods, 16, 2019
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2BO5
 | | Bovine oligomycin sensitivity conferral protein N-terminal domain | | 分子名称: | ATP SYNTHASE OLIGOMYCIN SENSITIVITY CONFERRAL PROTEIN | | 著者 | Carbajo, R.J, Kellas, F.A, Runswick, M.J, Montgomery, M.G, Walker, J.E, Neuhaus, D. | | 登録日 | 2005-04-07 | | 公開日 | 2005-08-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the F1-binding domain of the stator of bovine F1Fo-ATPase and how it binds an alpha-subunit.
J. Mol. Biol., 351, 2005
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6EHO
 | | Dimer of the Sortilin Vps10p domain at low pH | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sortilin, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Thirup, S.S, Quistgaard, E.H, Januliene, D, Andersen, J.L, Nielsen, J.A. | | 登録日 | 2017-09-14 | | 公開日 | 2017-12-06 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Acidic Environment Induces Dimerization and Ligand Binding Site Collapse in the Vps10p Domain of Sortilin.
Structure, 25, 2017
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2BKW
 | | Yeast alanine:glyoxylate aminotransferase YFL030w | | 分子名称: | ALANINE-GLYOXYLATE AMINOTRANSFERASE 1, GLYOXYLIC ACID, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Meyer, P, Liger, D, Leulliot, N, Quevillon-Cheruel, S, Zhou, C.Z, Borel, F, Ferrer, J.L, Poupon, A, Janin, J, van Tilbeurgh, H. | | 登録日 | 2005-02-21 | | 公開日 | 2005-11-02 | | 最終更新日 | 2015-11-18 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Crystal Structure and Confirmation of the Alanine:Glyoxylate Aminotransferase Activity of the Yfl030W Yeast Protein
Biochimie, 87, 2005
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2BJN
 | | X-ray Structure of human TPC6 | | 分子名称: | GLYCEROL, SULFATE ION, TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B | | 著者 | Kummel, D, Mueller, J.J, Roske, Y, Misselwitz, R, Bussow, K, Heinemann, U. | | 登録日 | 2005-02-04 | | 公開日 | 2005-07-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Structure of the Trapp Subunit Tpc6 Suggests a Model for a Trapp Subcomplex.
Embo Rep., 6, 2005
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6P0Y
 | | Cryptosporidium parvum pyruvate kinase in complex with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Schormann, N, Chattopadhyay, D. | | 登録日 | 2019-05-17 | | 公開日 | 2019-08-21 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | An overview of structure, function, and regulation of pyruvate kinases.
Protein Sci., 28, 2019
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7R7M
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6FSW
 | | Structure of Archaeoglobus fulgidus SBDS protein at 1.9 Angstrom | | 分子名称: | DI(HYDROXYETHYL)ETHER, Ribosome maturation protein SDO1-like protein | | 著者 | Mazzorana, M, Foadi, J, Siliqi, D, Sanchez-Puig, N. | | 登録日 | 2018-02-20 | | 公開日 | 2018-03-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Conformational flexibility of proteins involved in ribosome biogenesis: investigations via Small Angle X-ray Scattering (SAXS)
Crystals, 8, 2018
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2BNK
 | | The structure of phage phi29 replication organizer protein p16.7 | | 分子名称: | EARLY PROTEIN GP16.7 | | 著者 | Albert, A, Asensio, J.L, Munoz-Espin, D, Gonzalez, C, Hermoso, J.A, Villar, L, Jimenez-Barbero, J, Salas, M, Meijer, W.J.J. | | 登録日 | 2005-03-28 | | 公開日 | 2005-04-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of the Functional Domain of {Varphi}29 Replication Organizer: Insights Into Oligomerization and DNA Binding.
J.Biol.Chem., 280, 2005
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6PCW
 | | Human PIM1 bound to benzothiophene inhibitor 213 | | 分子名称: | 4-[5-(cyclopropylcarbamoyl)thiophen-2-yl]-1-benzothiophene-2-carboxamide, GLYCEROL, Peptide, ... | | 著者 | Godoi, P.H.C, Santiago, A.S, Fala, A.M, Ramos, P.Z, Sriranganadane, D, Mascarello, A, Segretti, N, Azevedo, H, Guimaraes, C.R.W, Arruda, P, Elkins, J.M, Counago, R.M, Structural Genomics Consortium (SGC) | | 登録日 | 2019-06-18 | | 公開日 | 2019-07-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | PIM1 bound to benzothiophene inhibitor
To Be Published
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2BUD
 | | The solution structure of the chromo barrel domain from the males- absent on the first (MOF) protein | | 分子名称: | MALES-ABSENT ON THE FIRST PROTEIN | | 著者 | Nielsen, P.R, Nietlispach, D, Buscaino, A, Warner, R.J, Akhtar, A, Murzin, A.G, Murzina, N.V, Laue, E.D. | | 登録日 | 2005-06-09 | | 公開日 | 2005-06-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the Chromo Barrel Domain from the Mof Acetyltransferase
J.Biol.Chem., 280, 2005
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2BVB
 | | The C-terminal domain from Micronemal Protein 1 (MIC1) from Toxoplasma Gondii | | 分子名称: | MICRONEMAL PROTEIN 1 | | 著者 | Saouros, S, Edwards-Jones, B, Reiss, M, Sawmynaden, K, Cota, E, Simpson, P, Dowse, T.J, Jakle, U, Ramboarina, S, Shivarattan, T, Matthews, S, Soldati-Favre, D. | | 登録日 | 2005-06-23 | | 公開日 | 2005-10-12 | | 最終更新日 | 2021-06-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Novel Galectin-Like Domain from Toxoplasma Gondll Micronemal Protein 1 Assists the Folding, Assembly,and Transport of a Cell-Adhesion Complex.
J.Biol.Chem., 280, 2005
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4JV7
 | | Co-crystal structure of MDM2 with inhibitor (2S,5R,6S)-2-benzyl-5,6-bis(4-bromophenyl)-4-methylmorpholin-3-one | | 分子名称: | (2S,5R,6S)-2-benzyl-5,6-bis(4-bromophenyl)-4-methylmorpholin-3-one, E3 ubiquitin-protein ligase Mdm2, SULFATE ION | | 著者 | Huang, X, Gonzalez-Lopez de Turiso, F, Sun, D, Yosup, R, Bartberger, M.D, Beck, H.P, Cannon, J, Shaffer, P, Oliner, J.D, Olson, S.H, Medina, J.C. | | 登録日 | 2013-03-25 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Rational Design and Binding Mode Duality of MDM2-p53 Inhibitors.
J.Med.Chem., 56, 2013
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4JVR
 | | Co-crystal structure of MDM2 with inhibitor (2'S,3R,4'S,5'R)-N-(2-aminoethyl)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide | | 分子名称: | (2'S,3R,4'S,5'R)-N-(2-aminoethyl)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide, E3 ubiquitin-protein ligase Mdm2 | | 著者 | Huang, X, Gonzalez-Lopez de Turiso, F, Sun, D, Yosup, R, Bartberger, M.D, Beck, H.P, Cannon, J, Shaffer, P, Oliner, J.D, Olson, S.H, Medina, J.C. | | 登録日 | 2013-03-26 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Rational Design and Binding Mode Duality of MDM2-p53 Inhibitors.
J.Med.Chem., 56, 2013
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6PIL
 | | Antibody scFv-M204 monomeric state | | 分子名称: | CHLORIDE ION, scFv-M204 antibody | | 著者 | Abskharon, R, Sawaya, M.R, Seidler, P.M, Cascio, D, Eisenberg, D.S. | | 登録日 | 2019-06-26 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease.
J.Biol.Chem., 295, 2020
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2C5B
 | | X-ray crystal structure of 5'-fluorodeoxyadenosine synthase from Streptomyces cattleya complexed with 2'deoxy-5'deoxy-fluoroadenosine. | | 分子名称: | 5'-FLUORO-2',5'-DIDEOXYADENOSINE, 5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE, METHIONINE | | 著者 | McEwan, A.R, Deng, H, McGlinchey, R.P, Robinson, D.A, O'Hagan, D, Naismith, J.H, Spencer, J. | | 登録日 | 2005-10-26 | | 公開日 | 2007-02-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Substrate Specificity in Enzymatic Fluorination. The Fluorinase from Streptomyces Cattleya Accepts 2'-Deoxyadenosine Substrates.
Org.Biomol.Chem., 4, 2006
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2BOK
 | | Factor Xa - cation | | 分子名称: | COAGULATION FACTOR X, SODIUM ION, [AMINO (4-{(3AS,4R,8AS,8BR)-1,3-DIOXO-2- [3-(TRIMETHYLAMMONIO) PROPYL]DECAHYDROPYRROLO[3,4-A] PYRROLIZIN-4-YL}PHENYL) METHYLENE]AMMONIUM | | 著者 | Morgenthaler, M, Schaerer, K, Paulini, R, Obst-Sander, U, Banner, D.W, Schlatter, D, Benz, J, Stihle, M, Diederich, F. | | 登録日 | 2005-04-12 | | 公開日 | 2005-06-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Quantification of Cation-Pi Interactions in Protein-Ligand Complexes: Crystal-Structure Analysis of Factor Xa Bound to a Quaternary Ammonium Ion Ligand
Angew.Chem.Int.Ed.Engl., 44, 2005
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2BYO
 | | Crystal structure of Mycobacterium tuberculosis lipoprotein LppX (Rv2945c) | | 分子名称: | ACETATE ION, ALPHA-LINOLENIC ACID, D-MALATE, ... | | 著者 | Sulzenbacher, G, Canaan, S, Roig-Zamboni, V, Maurin, D, Gicquel, B, Bourne, Y. | | 登録日 | 2005-08-03 | | 公開日 | 2006-03-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Lppx is a Lipoprotein Required for the Translocation of Phthiocerol Dimycocerosates to the Surface of Mycobacterium Tuberculosis.
Embo J., 25, 2006
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2BZM
 | | Solution structure of the primary host recognition region of complement factor H | | 分子名称: | COMPLEMENT FACTOR H | | 著者 | Herbert, A.P, Uhrin, D, Lyon, M, Pangburn, M.K, Barlow, P.N. | | 登録日 | 2005-08-18 | | 公開日 | 2006-03-22 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Disease-Associated Sequence Variations Congregate in a Polyanion Recognition Patch on Human Factor H Revealed in Three-Dimensional Structure.
J.Biol.Chem., 281, 2006
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2BDX
 | | X-ray Crystal Structure of dihydromicrocystin-LA bound to Protein Phosphatase-1 | | 分子名称: | DIHYDROMICROCYSTIN-LA, MANGANESE (II) ION, Serine/threonine protein phosphatase PP1-gamma catalytic subunit | | 著者 | Maynes, J.T, Luu, H.A, Cherney, M.M, Andersen, R.J, Williams, D, Holmes, C.F, James, M.N. | | 登録日 | 2005-10-21 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structures of Protein Phosphatase-1 Bound to Motuporin and Dihydromicrocystin-LA: Elucidation of the Mechanism of Enzyme Inhibition by Cyanobacterial Toxins.
J.Mol.Biol., 356, 2006
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3MHO
 | | Crystal structure of human carbonic anhydrase isozyme II with 4-[N-(6-chloro-5-formyl-2-methylthiopyrimidin-4-yl)amino]benzenesulfonamide | | 分子名称: | 4-{[6-chloro-5-formyl-2-(methylsulfanyl)pyrimidin-4-yl]amino}benzenesulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | | 著者 | Grazulis, S, Manakova, E, Golovenko, D, Sukackaite, R. | | 登録日 | 2010-04-08 | | 公開日 | 2010-10-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | 4-[N-(Substituted 4-pyrimidinyl)amino]benzenesulfonamides as inhibitors of carbonic anhydrase isozymes I, II, VII, and XIII
Bioorg.Med.Chem., 18, 2010
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2DYP
 | | Crystal Structure of LILRB2(LIR2/ILT4/CD85d) complexed with HLA-G | | 分子名称: | 9 Mer Peptide From Histone H2A.x, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | 著者 | Shiroishi, M, Kuroki, K, Rasubala, L, Kohda, D, Maenaka, K. | | 登録日 | 2006-09-15 | | 公開日 | 2006-11-07 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)
Proc.Natl.Acad.Sci.Usa, 103, 2006
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