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1K6Q

Crystal structure of antibody Fab fragment D3

Summary for 1K6Q
Entry DOI10.2210/pdb1k6q/pdb
Related1AHW 1FGN 1JPS 1JPT
Descriptorimmunoglobulin Fab D3, light chain, immunoglobulin Fab D3, heavy chain (3 entities in total)
Functional Keywordsantigen-antibody recognition, blood coagulation, tissue factor, immune system
Biological sourceMus musculus (house mouse)
More
Total number of polymer chains2
Total formula weight46446.47
Authors
Faelber, K.,Kelley, R.F.,Kirchhofer, D.,Muller, Y.A. (deposition date: 2001-10-17, release date: 2002-04-17, Last modification date: 2024-04-03)
Primary citationFaelber, K.,Kelley, R.F.,Kirchhofer, D.,Muller, Y.A.
The crystal structure of murine Fab D3 at 2.4 A resolution in comparison with the humanised Fab D3h44 (1.85A) provides structural insight into the humanisation process of the D3 anti-tissue factor antibody
To be Published,
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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