6U2G
| BRAF-MEK complex with AMP-PCP bound to BRAF | 分子名称: | Dual specificity mitogen-activated protein kinase kinase 1, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | 著者 | Liau, N.P.D, Wendorff, T, Hymowitz, S, Sudhamsu, J. | 登録日 | 2019-08-19 | 公開日 | 2019-08-28 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.886 Å) | 主引用文献 | Negative regulation of RAF kinase activity by ATP is overcome by 14-3-3-induced dimerization. Nat.Struct.Mol.Biol., 27, 2020
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8GW1
| A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors | 分子名称: | Helicase, MANGANESE (II) ION, Non-structural protein 7, ... | 著者 | Yan, L, Rao, Z, Lou, Z. | 登録日 | 2022-09-16 | 公開日 | 2023-10-25 | 最終更新日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | 主引用文献 | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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5XOI
| The structure of OsALKBH1 | 分子名称: | MANGANESE (II) ION, Oxidoreductase, 2OG-Fe oxygenase family protein, ... | 著者 | Wang, C, Guo, Y, Zeng, Z. | 登録日 | 2017-05-28 | 公開日 | 2018-06-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Identification and analysis of adenine N6-methylation sites in the rice genome. Nat Plants, 4, 2018
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3E87
| Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors | 分子名称: | Glycogen synthase kinase-3 beta peptide, N-[(1S)-2-amino-1-phenylethyl]-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide, RAC-beta serine/threonine-protein kinase | 著者 | Concha, N.O, Elkins, P.A, Smallwood, A, Ward, P. | 登録日 | 2008-08-19 | 公開日 | 2008-10-14 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Aminofurazans as potent inhibitors of AKT kinase Bioorg.Med.Chem.Lett., 19, 2009
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5XK1
| Structure of 8-mer DNA3 | 分子名称: | DNA (5'-D(*GP*GP*AP*GP*CP*CP*CP*C)-3') | 著者 | Liu, H.H, Gan, J.H. | 登録日 | 2017-05-04 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | 主引用文献 | A DNA Structure Containing AgI -Mediated G:G and C:C Base Pairs. Angew. Chem. Int. Ed. Engl., 56, 2017
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7CSZ
| Crystal structure of the N-terminal tandem RRM domains of RBM45 in complex with single-stranded DNA | 分子名称: | DNA (5'-D(*CP*GP*AP*CP*GP*GP*GP*AP*CP*GP*C)-3'), RNA-binding protein 45 | 著者 | Chen, X, Yang, Z, Wang, W, Wang, M. | 登録日 | 2020-08-17 | 公開日 | 2021-02-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for RNA recognition by the N-terminal tandem RRM domains of human RBM45. Nucleic Acids Res., 49, 2021
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6A0Q
| The crystal structure of Lpg2622_E64 complex | 分子名称: | Lpg2622, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE | 著者 | Gong, X, Ge, H. | 登録日 | 2018-06-06 | 公開日 | 2018-09-12 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural characterization of the hypothetical protein Lpg2622, a new member of the C1 family peptidases from Legionella pneumophila FEBS Lett., 592, 2018
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7C8D
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6LHW
| Structure of N-terminal and C-terminal domains of FANCA | 分子名称: | Fanconi anemia complementation group A | 著者 | Jeong, E, Lee, S, Shin, J, Kim, Y, Kim, J, Scharer, O, Kim, Y, Kim, H, Cho, Y. | 登録日 | 2019-12-10 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.84 Å) | 主引用文献 | Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex. Nucleic Acids Res., 48, 2020
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8GWM
| SARS-CoV-2 E-RTC bound with MMP-nsp9 and GMPPNP | 分子名称: | 2'-deoxy-2'-fluoro-2'-methyluridine 5'-(trihydrogen diphosphate), Helicase, Non-structural protein 7, ... | 著者 | Yan, L.M, Rao, Z.H, Lou, Z.Y. | 登録日 | 2022-09-17 | 公開日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | 主引用文献 | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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3E8D
| Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors | 分子名称: | 4-[2-(4-amino-2,5-dihydro-1,2,5-oxadiazol-3-yl)-6-{[(1S)-3-amino-1-phenylpropyl]oxy}-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol, Glycogen synthase kinase-3 beta peptide, RAC-beta serine/threonine-protein kinase | 著者 | Concha, N.O, Elkins, P.A, Smallwood, A, Ward, P. | 登録日 | 2008-08-19 | 公開日 | 2008-10-14 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Aminofurazans as potent inhibitors of AKT kinase Bioorg.Med.Chem.Lett., 19, 2009
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1AKN
| STRUCTURE OF BILE-SALT ACTIVATED LIPASE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BILE-SALT ACTIVATED LIPASE | 著者 | Wang, X, Zhang, X. | 登録日 | 1997-05-23 | 公開日 | 1998-05-27 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The crystal structure of bovine bile salt activated lipase: insights into the bile salt activation mechanism. Structure, 5, 1997
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7CI1
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7C2S
| Helical reconstruction of Dengue virus serotype 3 complexed with Fab C10 | 分子名称: | Heavy chain of Fab C10, envelope protein, light chain of Fab C10 | 著者 | Morrone, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Zhang, S, Lok, S.M. | 登録日 | 2020-05-09 | 公開日 | 2020-07-08 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (10.4 Å) | 主引用文献 | High flavivirus structural plasticity demonstrated by a non-spherical morphological variant. Nat Commun, 11, 2020
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4P7I
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7CI2
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7C2T
| Helical reconstruction of Zika virus complexed with Fab C10 | 分子名称: | Heavy chain from Fab C10, Light chain from Fab C10, M protein, ... | 著者 | Morrone, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Zhang, S, Lok, S.M. | 登録日 | 2020-05-09 | 公開日 | 2020-07-08 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | 主引用文献 | High flavivirus structural plasticity demonstrated by a non-spherical morphological variant. Nat Commun, 11, 2020
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3E8E
| Crystal structures of the kinase domain of PKA in complex with ATP-competitive inhibitors | 分子名称: | 4-[2-(4-amino-2,5-dihydro-1,2,5-oxadiazol-3-yl)-6-{[(1S)-3-amino-1-phenylpropyl]oxy}-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol, PKI inhibitor peptide, cAMP-dependent protein kinase catalytic subunit alpha | 著者 | Concha, N.O, Elkins, P.A, Smallwood, A, Ward, P. | 登録日 | 2008-08-19 | 公開日 | 2008-11-18 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Aminofurazans as potent inhibitors of AKT kinase Bioorg.Med.Chem.Lett., 19, 2009
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6LHV
| Structure of FANCA and FANCG Complex | 分子名称: | Fanconi anemia complementation group A, Fanconi anemia complementation group G | 著者 | Jeong, E, Lee, S, Shin, J, Kim, Y, Scharer, O, Kim, Y, Kim, H, Cho, Y. | 登録日 | 2019-12-10 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.59 Å) | 主引用文献 | Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex. Nucleic Acids Res., 48, 2020
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3QLH
| HIV-1 Reverse Transcriptase in Complex with Manicol at the RNase H Active Site and TMC278 (Rilpivirine) at the NNRTI Binding Pocket | 分子名称: | (2S)-5,7-dihydroxy-9-methyl-2-(prop-1-en-2-yl)-1,2,3,4-tetrahydro-6H-benzo[7]annulen-6-one, 1,2-ETHANEDIOL, 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, ... | 著者 | Himmel, D.M, Wojtak, K, Bauman, J.D, Arnold, E. | 登録日 | 2011-02-02 | 公開日 | 2011-12-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Synthesis, activity, and structural analysis of novel alpha-hydroxytropolone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H. J.Med.Chem., 54, 2011
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6LDF
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6LDE
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6LDG
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5XEG
| The structure of OsALKBH1 | 分子名称: | 2-OXOGLUTARIC ACID, MANGANESE (II) ION, Oxidoreductase, ... | 著者 | Wang, C, Guo, Y, Zeng, Z. | 登録日 | 2017-04-05 | 公開日 | 2018-06-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Identification and analysis of adenine N6-methylation sites in the rice genome. Nat Plants, 4, 2018
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8HJ4
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