7VFX
 
 | The structure of Formyl Peptide Receptor 1 in complex with Gi and peptide agonist fMIFL | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Wang, X.K, Chen, G, Liao, Q.W, Du, Y, Hu, H.L, Ye, D.Q. | 登録日 | 2021-09-14 | 公開日 | 2022-09-21 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns. Nat Commun, 13, 2022
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8JKU
 
 | Ancestral imine reductase N559 | 分子名称: | Ancestral imine reductase N559, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Zhu, X.X, Zheng, G.W. | 登録日 | 2023-06-01 | 公開日 | 2023-08-09 | 最終更新日 | 2024-12-11 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | Evolutionary insights into the stereoselectivity of imine reductases based on ancestral sequence reconstruction. Nat Commun, 15, 2024
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7V4X
 
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7V50
 
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7V51
 
 | BVMO_negative mutant D432V | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Putative flavin-binding monooxygenase | 著者 | Wu, Y, Yu, H.-L. | 登録日 | 2021-08-16 | 公開日 | 2023-02-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Precise regulation of the substrate selectivity of Baeyer-Villiger monooxygenase to minimize overoxidation of prazole sulfoxides. CHINESE J CATAL, 51, 2023
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8ZNZ
 
 | CD73 bound with HB0045 | 分子名称: | 5'-nucleotidase, CALCIUM ION, HB0038 Fab heavy chain, ... | 著者 | Xu, J, Wan, L, He, Y. | 登録日 | 2024-05-28 | 公開日 | 2025-02-05 | 最終更新日 | 2025-02-19 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | An antibody cocktail targeting two different CD73 epitopes enhances enzyme inhibition and tumor control. Nat Commun, 15, 2024
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7YVC
 
 | Aplysia californica FaNaC in apo state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Chen, Q.F, Liu, F.L, Dang, Y, Feng, H, Zhang, Z, Ye, S. | 登録日 | 2022-08-19 | 公開日 | 2023-08-09 | 最終更新日 | 2025-07-02 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure and mechanism of a neuropeptide-activated channel in the ENaC/DEG superfamily. Nat.Chem.Biol., 19, 2023
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7YVB
 
 | Aplysia californica FaNaC in ligand bound state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FMRFamide-gated Na+ channel, ... | 著者 | Chen, Q.F, Liu, F.L, Dang, Y, Feng, H, Zhang, Z, Ye, S. | 登録日 | 2022-08-19 | 公開日 | 2023-08-09 | 最終更新日 | 2025-06-25 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structure and mechanism of a neuropeptide-activated channel in the ENaC/DEG superfamily. Nat.Chem.Biol., 19, 2023
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8HDV
 
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8HDU
 
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5Z9S
 
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8HYA
 
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7E5Y
 
 | Molecular basis for neutralizing antibody 2B11 targeting SARS-CoV-2 RBD | 分子名称: | 2B11 Fab Heavy chain, 2B11 Fab Light chain, Spike protein S1 | 著者 | Wu, H, Yu, F, Wang, Q.S, Zhou, H, Wang, W.W, Zhao, T, Pan, Y.B, Yang, X.M. | 登録日 | 2021-02-21 | 公開日 | 2021-06-23 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (3.59 Å) | 主引用文献 | Screening of potent neutralizing antibodies against SARS-CoV-2 using convalescent patients-derived phage-display libraries. Cell Discov, 7, 2021
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7CI3
 
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7CR5
 
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7FDK
 
 | SARS-COV-2 Spike RBDMACSp36 binding to mACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 | 著者 | Wang, X, Cao, L. | 登録日 | 2021-07-16 | 公開日 | 2021-08-25 | 最終更新日 | 2024-10-30 | 実験手法 | ELECTRON MICROSCOPY (3.69 Å) | 主引用文献 | Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2. Nat Commun, 12, 2021
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7FDH
 
 | SARS-COV-2 Spike RBDMACSp25 binding to hACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 | 著者 | Wang, X, Cao, L. | 登録日 | 2021-07-16 | 公開日 | 2021-08-25 | 最終更新日 | 2025-07-02 | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | 主引用文献 | Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2. Nat Commun, 12, 2021
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7FDI
 
 | SARS-COV-2 Spike RBDMACSp36 binding to hACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 | 著者 | Wang, X, Cao, L. | 登録日 | 2021-07-16 | 公開日 | 2021-08-25 | 最終更新日 | 2025-07-02 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2. Nat Commun, 12, 2021
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7FDG
 
 | SARS-COV-2 Spike RBDMACSp6 binding to hACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 | 著者 | Wang, X, Cao, L. | 登録日 | 2021-07-16 | 公開日 | 2021-08-25 | 最終更新日 | 2025-07-02 | 実験手法 | ELECTRON MICROSCOPY (3.69 Å) | 主引用文献 | Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2. Nat Commun, 12, 2021
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6BNR
 
 | Carbonmonoxy hemoglobin in complex with the antisickling agent 5-methoxy-2-(pyridin-2-ylmethoxy)benzaldehyde (INN310) | 分子名称: | 2-[(4-methoxy-2-methylphenoxy)methyl]pyridine, CARBON MONOXIDE, Hemoglobin subunit alpha, ... | 著者 | Pagare, P.P, Musayev, F.N, Safo, M.K. | 登録日 | 2017-11-17 | 公開日 | 2018-09-05 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Rational design of pyridyl derivatives of vanillin for the treatment of sickle cell disease. Bioorg. Med. Chem., 26, 2018
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8J1I
 
 | Crystal Structure of EphA8/SASH1 Complex | 分子名称: | Ephrin type-A receptor 8, SAM and SH3 domain-containing protein 1 | 著者 | Liu, W, Li, J, Ding, Y. | 登録日 | 2023-04-12 | 公開日 | 2024-02-28 | 最終更新日 | 2024-09-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | SASH1: A Novel Eph Receptor Partner and Insights into SAM-SAM Interactions. J.Mol.Biol., 435, 2023
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6M6D
 
 | Structure of HPPD complexed with a synthesized inhibitor | 分子名称: | 1,5-dimethyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-(3-trimethylsilylprop-2-ynyl)quinazoline-2,4-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | 著者 | Lin, H.-Y, Yang, W.-C, Yang, G.-F. | 登録日 | 2020-03-14 | 公開日 | 2021-03-10 | 最終更新日 | 2024-11-13 | 実験手法 | X-RAY DIFFRACTION (1.842 Å) | 主引用文献 | Structure-Guided Discovery of Silicon-Containing Subnanomolar Inhibitor of Hydroxyphenylpyruvate Dioxygenase as a Potential Herbicide. J.Agric.Food Chem., 69, 2021
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6DI4
 
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6DKJ
 
 | human GIPR ECD and Fab complex | 分子名称: | 1,2-ETHANEDIOL, Fab heavy chain, Fab light chain, ... | 著者 | Min, X, Wang, Z. | 登録日 | 2018-05-29 | 公開日 | 2019-05-08 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models. Sci Transl Med, 10, 2018
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7XDS
 
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