6M6D

Structure of HPPD complexed with a synthesized inhibitor

Summary for 6M6D

Entry DOI	10.2210/pdb6m6d/pdb
Descriptor	4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION, 1,5-dimethyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-(3-trimethylsilylprop-2-ynyl)quinazoline-2,4-dione, ... (4 entities in total)
Functional Keywords	inhibitor, complex, oxidoreductase
Biological source	Arabidopsis thaliana (Mouse-ear cress)
Total number of polymer chains	1
Total formula weight	49371.31
Authors	Lin, H.-Y.,Yang, W.-C.,Yang, G.-F. (deposition date: 2020-03-14, release date: 2021-03-10, Last modification date: 2023-11-29)
Primary citation	Qu, R.Y.,Nan, J.X.,Yan, Y.C.,Chen, Q.,Ndikuryayo, F.,Wei, X.F.,Yang, W.C.,Lin, H.Y.,Yang, G.F. Structure-Guided Discovery of Silicon-Containing Subnanomolar Inhibitor of Hydroxyphenylpyruvate Dioxygenase as a Potential Herbicide. J.Agric.Food Chem., 69:459-473, 2021 Cited by PubMed: 33395281 DOI: 10.1021/acs.jafc.0c03844 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.842 Å)

Structure validation