6M6D

Structure of HPPD complexed with a synthesized inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003868	molecular_function	4-hydroxyphenylpyruvate dioxygenase activity
A	0005506	molecular_function	iron ion binding
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0006559	biological_process	L-phenylalanine catabolic process
A	0006572	biological_process	L-tyrosine catabolic process
A	0009072	biological_process	aromatic amino acid metabolic process
A	0009507	cellular_component	chloroplast
A	0010189	biological_process	vitamin E biosynthetic process
A	0010236	biological_process	plastoquinone biosynthetic process
A	0016117	biological_process	carotenoid biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0016701	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	0051213	molecular_function	dioxygenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue CO A 501

Chain	Residue
A	HIS226
A	HIS308
A	GLU394
A	NJX502
A	HOH644

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site_id	AC2
Number of Residues	15
Details	binding site for residue NJX A 502

Chain	Residue
A	ARG290
A	HIS308
A	PHE381
A	GLU394
A	PHE419
A	GLY420
A	ASN423
A	PHE424
A	LEU427
A	CO501
A	HOH644
A	HIS226
A	SER267
A	PRO280
A	ASN282

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:15301540

Chain	Residue	Details
A	HIS226
A	HIS308
A	GLU394

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