9IV1
 
 | | Identification, structure and agonist design of an androgen membrane receptor. | | 分子名称: | 5-ALPHA-DIHYDROTESTOSTERONE, Adhesion G-protein coupled receptor D1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Ping, Y.Q, Yang, Z. | | 登録日 | 2024-07-22 | | 公開日 | 2025-02-12 | | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | | 主引用文献 | Identification, structure, and agonist design of an androgen membrane receptor.
Cell, 2025
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9IV2
 | | Identification, structure and agonist design of an androgen membrane receptor. | | 分子名称: | 5-ALPHA-DIHYDROTESTOSTERONE, Adhesion G-protein coupled receptor D1, Gs protein alpha subunit, ... | | 著者 | Ping, Y.Q, Yang, Z. | | 登録日 | 2024-07-22 | | 公開日 | 2025-02-12 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | Identification, structure, and agonist design of an androgen membrane receptor.
Cell, 2025
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7RRG
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9MCZ
 | | Crystal structure of the transpeptidase domain of PBP2 from the Neisseria gonorrhoeae cephalosporin decreased susceptibility strain 35/02 in complex with boronate inhibitor VNRX-6884 | | 分子名称: | (3R)-3-{[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-phosphonophenyl)acetyl]amino}-2-hydroxy-3,4-dihydro-2H-1,2-benzoxaborinine-8-carboxylic acid, Penicillin-binding protein 2 | | 著者 | Stratton, C.M, Bala, S, Davies, C. | | 登録日 | 2024-12-05 | | 公開日 | 2025-01-22 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | A new class of penicillin-binding protein inhibitors to address drug-resistant Neisseria gonorrhoeae.
Biorxiv, 2024
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9MD0
 | | Crystal structure of the transpeptidase domain of PBP2 from the Neisseria gonorrhoeae cephalosporin decreased susceptibility strain 35/02 in complex with boronate inhibitor VNRX-6752 | | 分子名称: | (3R)-3-({(2R)-2-(4-carboxyphenyl)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]acetyl}amino)-2-hydroxy-3,4-dihydro-2H-1,2-benzoxaborinine-8-carboxylic acid, Penicillin-binding protein 2 | | 著者 | Stratton, C.M, Bala, S, Davies, C. | | 登録日 | 2024-12-05 | | 公開日 | 2025-01-22 | | 実験手法 | X-RAY DIFFRACTION (2.613 Å) | | 主引用文献 | A new class of penicillin-binding protein inhibitors to address drug-resistant Neisseria gonorrhoeae.
Biorxiv, 2024
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5C5S
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5J8R
 | | Crystal Structure of the Catalytic Domain of Human Protein Tyrosine Phosphatase non-receptor Type 12 - K61R mutant | | 分子名称: | Tyrosine-protein phosphatase non-receptor type 12 | | 著者 | Li, H, Yang, F, Xu, Y.F, Wang, W.J, Xiao, P, Yu, X, Sun, J.P. | | 登録日 | 2016-04-08 | | 公開日 | 2016-04-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.043 Å) | | 主引用文献 | Crystal structure and substrate specificity of PTPN12.
Cell Rep, 15, 2016
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7L1D
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7L1C
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7L1B
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6ODL
 | | Crystal structure of GluN2A agonist binding domain with 4-butyl-(S)-CCG-IV | | 分子名称: | (1S,2R)-2-[(S)-amino(carboxy)methyl]-1-butylcyclopropane-1-carboxylic acid, Glutamate receptor ionotropic, NMDA 2A,Glutamate receptor ionotropic, ... | | 著者 | Mou, T.C, Clausen, R.P, Sprang, S.R, Hansen, K.B. | | 登録日 | 2019-03-26 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Stereoselective synthesis of novel 2'-(S)-CCG-IV analogues as potent NMDA receptor agonists.
Eur.J.Med.Chem., 212, 2021
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8W8Q
 | | Cryo-EM structure of the GPR101-Gs complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Sun, J.P, Gao, N, Yu, X, Wang, G.P, Yang, F, Wang, J.Y, Yang, Z, Guan, Y. | | 登録日 | 2023-09-04 | | 公開日 | 2024-01-03 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Structure of GPR101-Gs enables identification of ligands with rejuvenating potential.
Nat.Chem.Biol., 20, 2024
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8W8R
 | | Cryo-EM structure of the AA-14-bound GPR101-Gs complex | | 分子名称: | 1-(4-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]thiourea, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Sun, J.P, Yu, X, Gao, N, Yang, F, Wang, J.Y, Yang, Z, Guan, Y, Wang, G.P. | | 登録日 | 2023-09-04 | | 公開日 | 2024-01-03 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structure of GPR101-Gs enables identification of ligands with rejuvenating potential.
Nat.Chem.Biol., 20, 2024
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8W8S
 | | Cryo-EM structure of the AA14-bound GPR101 complex | | 分子名称: | 1-(4-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]thiourea, Probable G-protein coupled receptor 101 | | 著者 | Sun, J.P, Yu, X, Gao, N, Yang, F, Wang, J.Y, Yang, Z, Guan, Y, Wang, G.P. | | 登録日 | 2023-09-04 | | 公開日 | 2024-01-03 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structure of GPR101-Gs enables identification of ligands with rejuvenating potential.
Nat.Chem.Biol., 20, 2024
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8X9U
 | | Identification, structure and agonist design of an androgen membrane receptor | | 分子名称: | (5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-1,10,13-trimethyl-4,5,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one, Adhesion G-protein coupled receptor D1, Gs protein alpha subunit, ... | | 著者 | Ping, Y.Q, Yang, Z. | | 登録日 | 2023-12-01 | | 公開日 | 2025-02-12 | | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | | 主引用文献 | Identification, structure, and agonist design of an androgen membrane receptor.
Cell, 2025
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8X9S
 | | Identification, structure and agonist design of an androgen membrane receptor. | | 分子名称: | 5-ALPHA-DIHYDROTESTOSTERONE, Adhesion G-protein coupled receptor D1, Gs protein alpha subunit, ... | | 著者 | Ping, Y.Q, Yang, Z. | | 登録日 | 2023-12-01 | | 公開日 | 2025-02-12 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | Identification, structure, and agonist design of an androgen membrane receptor.
Cell, 2025
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8X9T
 | | Identification, structure and agonist design of an androgen membrane receptor | | 分子名称: | Adhesion G-protein coupled receptor D1, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Ping, Y.Q, Yang, Z. | | 登録日 | 2023-12-01 | | 公開日 | 2025-02-12 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Identification, structure, and agonist design of an androgen membrane receptor.
Cell, 2025
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2N35
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8XDA
 | | Cryo-EM structure of urea bound human urea transporter A2. | | 分子名称: | UREA, Urea transporter 2 | | 著者 | Huang, S, Liu, L, Sun, J, Zhizheng, H. | | 登録日 | 2023-12-10 | | 公開日 | 2024-12-04 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural insights into the mechanisms of urea permeation and distinct inhibition modes of urea transporters.
Nat Commun, 15, 2024
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8XDH
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8XDF
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8XD9
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8XDG
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8XDE
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8XDD
 | | Cryo-EM structure of human urea transporter A2. | | 分子名称: | 1-(3-methoxyphenyl)methanamine, 8-hydroxyquinoline-2-carboxylic acid, Urea transporter 2 | | 著者 | Huang, S, Liu, L, Sun, J. | | 登録日 | 2023-12-10 | | 公開日 | 2024-12-04 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural insights into the mechanisms of urea permeation and distinct inhibition modes of urea transporters.
Nat Commun, 15, 2024
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