6ODL

Crystal structure of GluN2A agonist binding domain with 4-butyl-(S)-CCG-IV

Summary for 6ODL

Entry DOI	10.2210/pdb6odl/pdb
Descriptor	Glutamate receptor ionotropic, NMDA 2A,Glutamate receptor ionotropic, NMDA 2A, (1S,2R)-2-[(S)-amino(carboxy)methyl]-1-butylcyclopropane-1-carboxylic acid (3 entities in total)
Functional Keywords	nmda receptor, antagonist, transport protein, receptor
Biological source	Rattus norvegicus (Rat) More
Total number of polymer chains	2
Total formula weight	63138.37
Authors	Mou, T.C.,Clausen, R.P.,Sprang, S.R.,Hansen, K.B. (deposition date: 2019-03-26, release date: 2020-04-01, Last modification date: 2023-10-11)
Primary citation	Maolanon, A.,Papangelis, A.,Kawiecki, D.,Mou, T.C.,Syrenne, J.T.,Yi, F.,Hansen, K.B.,Clausen, R.P. Stereoselective synthesis of novel 2'-(S)-CCG-IV analogues as potent NMDA receptor agonists. Eur.J.Med.Chem., 212:113099-113099, 2021 Cited by PubMed: 33383257 DOI: 10.1016/j.ejmech.2020.113099 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation