6ODL
Crystal structure of GluN2A agonist binding domain with 4-butyl-(S)-CCG-IV
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutamate receptor ionotropic, NMDA 2A,Glutamate receptor ionotropic, NMDA 2A | polymer | 279 | 31353.9 | 2 | UniProt (Q00959) UniProt (G3V9C5) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Rat) | GluN2A,Glutamate [NMDA] receptor subunit epsilon-1,N-methyl D-aspartate receptor subtype 2A,NR2A |
| 2 | C, D (A, B) | (1S,2R)-2-[(S)-amino(carboxy)methyl]-1-butylcyclopropane-1-carboxylic acid | non-polymer | 215.2 | 2 | Chemie (M7V) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A, B: 7 - 142 (UniProt: Q00959)
A, B: 145 - 285 (UniProt: G3V9C5)
| PDB | External Database | Details |
|---|---|---|
| Gly 143 | - | linker |
| Thr 144 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62707.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 430.5 | |
| All* | Total formula weight | 63138.4 |
