6ODL

Crystal structure of GluN2A agonist binding domain with 4-butyl-(S)-CCG-IV

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015276	molecular_function	ligand-gated monoatomic ion channel activity
A	0016020	cellular_component	membrane
B	0015276	molecular_function	ligand-gated monoatomic ion channel activity
B	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue M7V A 301

Chain	Residue
A	HIS88
A	TYR214
A	ASP215
A	HOH415
A	SER114
A	THR116
A	ARG121
A	VAL169
A	PRO170
A	GLY172
A	SER173
A	THR174

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site_id	AC2
Number of Residues	11
Details	binding site for residue M7V B 301

Chain	Residue
B	HIS88
B	SER114
B	THR116
B	ARG121
B	PRO170
B	GLY172
B	SER173
B	THR174
B	TYR214
B	ASP215
B	HOH404

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16281028","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24462099","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27618671","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2A5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2A5T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NF4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NF8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I56","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I57","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I58","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I59","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JTY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16281028","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24462099","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27618671","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2A5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2A5T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NF4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NF8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I56","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I57","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I58","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JTY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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