3UNG
| Structure of the Cmr2 subunit of the CRISPR RNA silencing complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Cmr2dHD, ... | 著者 | Cocozaki, A.I, Ramia, N.F, Shao, Y, Hale, C.R, Terns, R.M, Terns, M.P, Li, H. | 登録日 | 2011-11-15 | 公開日 | 2012-03-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Structure of the Cmr2 Subunit of the CRISPR-Cas RNA Silencing Complex. Structure, 20, 2012
|
|
7CNU
| |
4Z7L
| Crystal structure of Cas6b | 分子名称: | Cas6b, RNA (5'-R(*GP*CP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*GP*C)-3'), SULFATE ION | 著者 | Li, H. | 登録日 | 2015-04-07 | 公開日 | 2016-04-13 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.503 Å) | 主引用文献 | A Non-Stem-Loop CRISPR RNA Is Processed by Dual Binding Cas6. Structure, 24, 2016
|
|
4Z7K
| |
1XN8
| Solution Structure of Bacillus subtilis Protein yqbG: The Northeast Structural Genomics Consortium Target SR215 | 分子名称: | Hypothetical protein yqbG | 著者 | Liu, G, Ma, L, Shen, Y, Acton, T, Atreya, H.S, Xiao, R, Joachimiak, A, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2004-10-04 | 公開日 | 2004-12-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR data collection and analysis protocol for high-throughput protein structure determination. Proc.Natl.Acad.Sci.Usa, 102, 2005
|
|
1XNE
| Solution Structure of Pyrococcus furiosus Protein PF0470: The Northeast Structural Genomics Consortium Target PfR14 | 分子名称: | hypothetical protein PF0469 | 著者 | Liu, G, Xiao, R, Parish, D, Ma, L, Sukumaran, D, Acton, T, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2004-10-04 | 公開日 | 2004-12-14 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR data collection and analysis protocol for high-throughput protein structure determination. Proc.Natl.Acad.Sci.Usa, 102, 2005
|
|
1XN6
| Solution Structure of Northeast Structural Genomics Target Protein BcR68 encoded in gene Q816V6 of B. cereus | 分子名称: | hypothetical protein BC4709 | 著者 | Liu, G, Acton, T, Parish, D, Ma, L, Xu, D, Xiao, R, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2004-10-04 | 公開日 | 2004-12-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR data collection and analysis protocol for high-throughput protein structure determination. Proc.Natl.Acad.Sci.Usa, 102, 2005
|
|
4Y87
| Crystal structure of phosphodiesterase 9 in complex with (R)-C33 (6-{[(1R)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) | 分子名称: | 6-{[(1R)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... | 著者 | Huang, M. | 登録日 | 2015-02-16 | 公開日 | 2015-09-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric Inhibitor. Mol.Pharmacol., 88, 2015
|
|
4Y86
| Crystal structure of PDE9 in complex with racemic inhibitor C33 | 分子名称: | 6-{[(1R)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, 6-{[(1S)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, ... | 著者 | Huang, M. | 登録日 | 2015-02-16 | 公開日 | 2015-09-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Structural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric Inhibitor. Mol.Pharmacol., 88, 2015
|
|
4Y8C
| Crystal structure of phosphodiesterase 9 in complex with (S)-C33 | 分子名称: | 6-{[(1S)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... | 著者 | Huang, M. | 登録日 | 2015-02-16 | 公開日 | 2015-09-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric Inhibitor. Mol.Pharmacol., 88, 2015
|
|
4MD6
| Crystal structure of PDE5 in complex with inhibitor 5R | 分子名称: | 3-(4-hydroxybenzyl)-1-(thiophen-2-yl)chromeno[2,3-c]pyrrol-9(2H)-one, MAGNESIUM ION, SULFATE ION, ... | 著者 | Cui, W, Huang, M, Shao, Y, Luo, H. | 登録日 | 2013-08-22 | 公開日 | 2014-07-09 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of 3-(4-hydroxybenzyl)-1-(thiophen-2-yl)chromeno[2,3-c]pyrrol-9(2H)-one as a phosphodiesterase-5 inhibitor and its complex crystal structure. Biochem Pharmacol, 89, 2014
|
|
1J4J
| Crystal Structure of Tabtoxin Resistance Protein (form II) complexed with an Acyl Coenzyme A | 分子名称: | ACETYL COENZYME *A, TABTOXIN RESISTANCE PROTEIN | 著者 | He, H, Ding, Y, Bartlam, M, Zhang, R, Duke, N, Joachimiak, A, Shao, Y, Cao, Z, Tang, H, Liu, Y, Jiang, F, Liu, J, Zhao, N, Rao, Z. | 登録日 | 2001-10-02 | 公開日 | 2003-06-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Crystal structure of tabtoxin resistance protein complexed with acetyl coenzyme A reveals the mechanism for beta-lactam acetylation. J.Mol.Biol., 325, 2003
|
|
7JM5
| Crystal structure of KDM4B in complex with QC6352 | 分子名称: | 3-[({(1R)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahydronaphthalen-1-yl}methyl)amino]pyridine-4-carboxylic acid, Lysine-specific demethylase 4B, NICKEL (II) ION, ... | 著者 | White, S.W, Yun, M. | 登録日 | 2020-07-31 | 公開日 | 2022-02-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Targeting KDM4 for treating PAX3-FOXO1-driven alveolar rhabdomyosarcoma. Sci Transl Med, 14, 2022
|
|
6UUM
| |
6UUL
| Crystal structure of broad and potent HIV-1 neutralizing antibody 438-D5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, D5 Fab Heavy Chain, ... | 著者 | Kumar, S, Wilson, I.A. | 登録日 | 2019-10-30 | 公開日 | 2020-09-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | A V H 1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite. Sci Adv, 6, 2020
|
|
6UUH
| |
6V6W
| |
5CD3
| |
5CD5
| |
2ZAK
| Orthorhombic crystal structure of precursor E. coli isoaspartyl peptidase/L-asparaginase (EcAIII) with active-site T179A mutation | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, L-asparaginase precursor, ... | 著者 | Michalska, K, Hernandez-Santoyo, A, Jaskolski, M. | 登録日 | 2007-10-07 | 公開日 | 2008-03-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Crystal packing of plant-type L-asparaginase from Escherichia coli Acta Crystallogr.,Sect.D, 64, 2008
|
|
6XJY
| |
6XJQ
| Crystal structure of a self-alkylating ribozyme - alkylated form with biotinylated epoxide substrate | 分子名称: | 2-{[(4R)-4-hydroxyhexyl]oxy}ethyl 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate, Fab HAVx Heavy Chain, Fab HAVx Light Chain, ... | 著者 | Koirala, D, Piccirilli, J.A. | 登録日 | 2020-06-24 | 公開日 | 2022-01-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.708 Å) | 主引用文献 | Structural basis for substrate binding and catalysis by a self-alkylating ribozyme. Nat.Chem.Biol., 18, 2022
|
|
6XJZ
| |
6XJW
| |
6CCW
| |