7A4M
| Cryo-EM structure of mouse heavy-chain apoferritin at 1.22 A | 分子名称: | FE (III) ION, Ferritin heavy chain, ZINC ION | 著者 | Nakane, T, Kotecha, A, Sente, A, Yamashita, K, McMullan, G, Masiulis, S, Brown, P.M.G.E, Grigoras, I.T, Malinauskaite, L, Malinauskas, T, Miehling, J, Yu, L, Karia, D, Pechnikova, E.V, de Jong, E, Keizer, J, Bischoff, M, McCormack, J, Tiemeijer, P, Hardwick, S.W, Chirgadze, D.Y, Murshudov, G, Aricescu, A.R, Scheres, S.H.W. | 登録日 | 2020-08-20 | 公開日 | 2020-10-28 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (1.22 Å) | 主引用文献 | Single-particle cryo-EM at atomic resolution. Nature, 587, 2020
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7A5V
| CryoEM structure of a human gamma-aminobutyric acid receptor, the GABA(A)R-beta3 homopentamer, in complex with histamine and megabody Mb25 in lipid nanodisc | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Nakane, T, Kotecha, A, Sente, A, Yamashita, K, McMullan, G, Masiulis, S, Brown, P.M.G.E, Grigoras, I.T, Malinauskaite, L, Malinauskas, T, Miehling, J, Yu, L, Karia, D, Pechnikova, E.V, de Jong, E, Keizer, J, Bischoff, M, McCormack, J, Tiemeijer, P, Hardwick, S.W, Chirgadze, D.Y, Murshudov, G, Aricescu, A.R, Scheres, S.H.W. | 登録日 | 2020-08-22 | 公開日 | 2020-11-18 | 最終更新日 | 2020-11-25 | 実験手法 | ELECTRON MICROSCOPY (1.7 Å) | 主引用文献 | Single-particle cryo-EM at atomic resolution. Nature, 587, 2020
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7NIT
| X-ray structure of a multidomain BbgIII from Bifidobacterium bifidum | 分子名称: | Beta-galactosidase, CALCIUM ION, GLYCEROL, ... | 著者 | Moroz, O.V, Blagova, E, Lebedev, A.A, Sanchez Rodriguez, F, Rigden, D.J, Tams, J.W, Wilting, R, Vester, J.K, Longhin, E, Krogh, K.B.R, Pache, R.A, Davies, G.J, Wilson, K.S. | 登録日 | 2021-02-14 | 公開日 | 2021-12-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Multitasking in the gut: the X-ray structure of the multidomain BbgIII from Bifidobacterium bifidum offers possible explanations for its alternative functions. Acta Crystallogr D Struct Biol, 77, 2021
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4DPD
| WILD TYPE PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PfDHFR-TS), DHF COMPLEX, NADP+, dUMP | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, DIHYDROFOLIC ACID, ... | 著者 | Yuthavong, Y, Vilaivan, T, Kamchonwongpaisan, S, Charman, S.A, McLennan, D.N, White, K.L, Vivas, L, Bongard, E, Chitnumsub, P, Tarnchompoo, B, Thongphanchang, C, Taweechai, S, Vanichtanakul, J, Arwon, U, Fantauzzi, P, Yuvaniyama, J, Charman, W.N, Matthews, D. | 登録日 | 2012-02-13 | 公開日 | 2012-11-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target Proc.Natl.Acad.Sci.USA, 109, 2012
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4DDR
| Human dihydrofolate reductase complexed with NADPH and P218 | 分子名称: | 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Yuthavong, Y, Tarnchompoo, B, Vilaivan, T, Chitnumsub, P, Kamchonwongpaisan, S, Charman, S.A, McLennan, D.N, White, K.L, Vivas, L, Bongard, E, Thongphanchang, C, Taweechai, S, Vanichtanankul, J, Rattanajak, R, Arwon, U, Fantauzzi, P, Yuvaniyama, J, Charman, W.N, Matthews, D. | 登録日 | 2012-01-19 | 公開日 | 2012-11-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target Proc.Natl.Acad.Sci.USA, 109, 2012
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4DP3
| Quadruple mutant (N51I+C59R+S108N+I164L) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with P218 and NADPH | 分子名称: | 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, Bifunctional dihydrofolate reductase-thymidylate synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Yuthavong, Y, Vilaivan, T, Kamchonwongpaisan, S, Charman, S.A, McLennan, D.N, White, K.L, Vivas, L, Bongard, E, Chitnumsub, P, Tarnchompoo, B, Thongphanchang, C, Taweechai, S, Vanichtanakul, J, Arwon, U, Fantauzzi, P, Yuvaniyama, J, Charman, W.N, Matthews, D. | 登録日 | 2012-02-13 | 公開日 | 2012-11-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target Proc.Natl.Acad.Sci.USA, 109, 2012
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4DPH
| Quadruple mutant (N51I+C59R+S108N+I164L) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with P65 and NADPH | 分子名称: | 2,4-diamino-6-methyl-5-[3-(2,4,5-trichlorophenoxy)propyloxy]pyrimidine, BETA-MERCAPTOETHANOL, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | 著者 | Yuthavong, Y, Vilaivan, T, Kamchonwongpaisan, S, Charman, S.A, McLennan, D.N, White, K.L, Vivas, L, Bongard, E, Chitnumsub, P, Tarnchompoo, B, Thongphanchang, C, Taweechai, S, Vanichtanakul, J, Arwon, U, Fantauzzi, P, Yuvaniyama, J, Charman, W.N, Matthews, D. | 登録日 | 2012-02-13 | 公開日 | 2012-11-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target Proc.Natl.Acad.Sci.USA, 109, 2012
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1L3W
| C-cadherin Ectodomain | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Boggon, T.J, Murray, J, Chappuis-Flament, S, Wong, E, Gumbiner, B.M, Shapiro, L. | 登録日 | 2002-03-01 | 公開日 | 2002-04-26 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | 主引用文献 | C-cadherin ectodomain structure and implications for cell adhesion mechanisms Science, 296, 2002
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4L4U
| Crystal structure of construct containing A. aeolicus NtrC1 receiver, central and DNA binding domains | 分子名称: | Transcriptional regulator (NtrC family) | 著者 | Vidangos, N.K, Maris, A.E, Young, A, Hong, E, Pelton, J.G, Batchelor, J.D, Wemmer, D.E. | 登録日 | 2013-06-09 | 公開日 | 2013-08-28 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure, function, and tethering of DNA-binding domains in sigma (54) transcriptional activators. Biopolymers, 99, 2013
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1R02
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4L5E
| Crystal structure of A. aeolicus NtrC1 DNA binding domain | 分子名称: | SULFATE ION, Transcriptional regulator (NtrC family) | 著者 | Young, A, Maris, A.E, Vidangos, N.K, Hong, E, Pelton, J.G, Batchelor, J.D, Wemmer, D.E. | 登録日 | 2013-06-10 | 公開日 | 2013-08-28 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Structure, function, and tethering of DNA-binding domains in sigma (54) transcriptional activators. Biopolymers, 99, 2013
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2A8B
| Crystal Structure of the Catalytic Domain of Human Tyrosine Phosphatase Receptor, Type R | 分子名称: | CHLORIDE ION, Receptor-type tyrosine-protein phosphatase R | 著者 | Ugochukwu, E, Eswaran, J, Barr, A, Longman, E, Arrowsmith, C, Edwards, A, Sundstrom, M, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2005-07-07 | 公開日 | 2005-07-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases. Biochem.J., 395, 2006
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2C46
| CRYSTAL STRUCTURE OF THE HUMAN RNA guanylyltransferase and 5'- phosphatase | 分子名称: | MRNA CAPPING ENZYME | 著者 | Debreczeni, J, Johansson, C, Longman, E, Gileadi, O, SavitskySmee, P, Smee, C, Bunkoczi, G, Ugochukwu, E, von Delft, F, Sundstrom, M, Weigelt, J, Arrowsmith, C, Edwards, A, Knapp, S. | 登録日 | 2005-10-15 | 公開日 | 2005-11-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal Structure of the Human RNA Guanylyltransferase and 5'-Phosphatase To be Published
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2A3K
| Crystal Structure of the Human Protein Tyrosine Phosphatase, PTPN7 (HePTP, Hematopoietic Protein Tyrosine Phosphatase) | 分子名称: | PHOSPHATE ION, protein tyrosine phosphatase, non-receptor type 7, ... | 著者 | Barr, A, Turnbull, A.P, Das, S, Eswaran, J, Debreczeni, J.E, Longmann, E, Smee, C, Burgess, N, Gileadi, O, Sundstrom, M, Arrowsmith, C, Edwards, A, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2005-06-24 | 公開日 | 2005-07-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | The crystal structure of human receptor protein tyrosine phosphatase kappa phosphatase domain 1. Protein Sci., 15, 2006
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2BWJ
| Structure of adenylate kinase 5 | 分子名称: | ADENOSINE MONOPHOSPHATE, ADENYLATE KINASE 5, CHLORIDE ION, ... | 著者 | Bunkoczi, G, Filippakopoulos, P, Fedorov, O, Jansson, A, Longman, E, Ugochukwu, E, Knapp, S, von Delft, F, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J. | 登録日 | 2005-07-14 | 公開日 | 2005-07-21 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of Adenylate Kinase 5 To be Published
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7CA3
| Cryo-EM structure of human GABA(B) receptor bound to the positive allosteric modulator rac-BHFF | 分子名称: | (3S)-5,7-ditert-butyl-3-oxidanyl-3-(trifluoromethyl)-1-benzofuran-2-one, CHOLESTEROL, Gamma-aminobutyric acid type B receptor subunit 1, ... | 著者 | Kim, Y, Jeong, E, Jeong, J, Kim, Y, Cho, Y. | 登録日 | 2020-06-08 | 公開日 | 2020-11-11 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structural Basis for Activation of the Heterodimeric GABA B Receptor. J.Mol.Biol., 432, 2020
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7CA5
| Cryo-EM structure of human GABA(B) receptor in apo state | 分子名称: | Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2 | 著者 | Kim, Y, Jeong, E, Jeong, J, Kim, Y, Cho, Y. | 登録日 | 2020-06-08 | 公開日 | 2020-11-11 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | 主引用文献 | Structural Basis for Activation of the Heterodimeric GABA B Receptor. J.Mol.Biol., 432, 2020
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7CUM
| Cryo-EM structure of human GABA(B) receptor bound to the antagonist CGP54626 | 分子名称: | (R)-(cyclohexylmethyl)[(2S)-3-{[(1S)-1-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropyl]phosphinic acid, CHOLESTEROL, Gamma-aminobutyric acid type B receptor subunit 1, ... | 著者 | Kim, Y, Jeong, E, Jeong, J, Kim, Y, Cho, Y. | 登録日 | 2020-08-23 | 公開日 | 2020-11-11 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Structural Basis for Activation of the Heterodimeric GABA B Receptor. J.Mol.Biol., 432, 2020
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2C7S
| Crystal structure of human protein tyrosine phosphatase kappa at 1.95A resolution | 分子名称: | ACETATE ION, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE KAPPA | 著者 | Debreczeni, J.E, Ugochukwu, E, Eswaran, J, Barr, A, Das, S, Burgess, N, Gileadi, O, Longman, E, von Delft, F, Knapp, S, Sundstron, M, Arrowsmith, C, Weigelt, J, Edwards, A. | 登録日 | 2005-11-28 | 公開日 | 2007-01-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The crystal structure of human receptor protein tyrosine phosphatase kappa phosphatase domain 1. Protein Sci., 15, 2006
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2ABY
| Solution structure of TA0743 from Thermoplasma acidophilum | 分子名称: | hypothetical protein TA0743 | 著者 | Kim, B, Jung, J, Hong, E, Yee, A, Arrowsmith, C.H, Lee, W. | 登録日 | 2005-07-18 | 公開日 | 2006-08-08 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of the conserved novel-fold protein TA0743 from Thermoplasma acidophilum. Proteins, 62, 2006
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5GOX
| Eukaryotic Rad50 Functions as A Rod-shaped Dimer | 分子名称: | DNA repair protein RAD50, GLYCEROL, ZINC ION | 著者 | Park, Y.B, Hohl, M, Padjasek, M, Jeong, E, Jin, K.S, Krezel, A, Petrini, J.H.J, Cho, Y. | 登録日 | 2016-07-30 | 公開日 | 2017-02-01 | 最終更新日 | 2017-03-15 | 実験手法 | X-RAY DIFFRACTION (2.405 Å) | 主引用文献 | Eukaryotic Rad50 functions as a rod-shaped dimer Nat. Struct. Mol. Biol., 24, 2017
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2C95
| Structure of adenylate kinase 1 in complex with P1,P4-di(adenosine) tetraphosphate | 分子名称: | ADENYLATE KINASE 1, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, MALONATE ION | 著者 | Bunkoczi, G, Filippakopoulos, P, Jansson, A, Longman, E, von Delft, F, Edwards, A, Arrowsmith, C, Sundstrom, M, Knapp, S. | 登録日 | 2005-12-09 | 公開日 | 2007-02-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Structure of Adenylate Kinase 1 in Complex with P1, P4-Di(Adenosine)Tetraphosphate To be Published
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2G1E
| Solution Structure of TA0895 | 分子名称: | hypothetical protein Ta0895 | 著者 | Yeo, I.Y, Hong, E, Jung, J, Lee, W, Yee, A, Arrowsmith, C.H. | 登録日 | 2006-02-14 | 公開日 | 2006-12-26 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of TA0895, a MoaD homologue from Thermoplasma acidophilum Proteins, 65, 2006
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2JRL
| Solution structure of the beryllofluoride-activated NtrC4 receiver domain dimer | 分子名称: | Transcriptional regulator (NtrC family) | 著者 | Lee, C, Hong, E, Doucleff, M, Pelton, J.G, Wemmer, D.E, Berkeley Structural Genomics Center (BSGC) | 登録日 | 2007-06-27 | 公開日 | 2008-07-01 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the Beryllofluoride-Activated NtrC4 Receiver Domain Dimer. To be Published
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6JLR
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