2C46

CRYSTAL STRUCTURE OF THE HUMAN RNA guanylyltransferase and 5'- phosphatase

Summary for 2C46

DescriptorMRNA CAPPING ENZYME (2 entities in total)
Functional Keywordsphosphatase, transferase, hydrolase, mrna processing, multifunctional enzyme, nucleotidyltransferase
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationNucleus  O60942
Total number of polymer chains4
Total molecular weight110752.75
Authors
Primary citation
Debreczeni, J.,Johansson, C.,Longman, E.,Gileadi, O.,Savitskysmee, P.,Smee, C.,Bunkoczi, G.,Ugochukwu, E.,von Delft, F.,Sundstrom, M.,Weigelt, J.,Arrowsmith, C.,Edwards, A.,Knapp, S.
Crystal Structure of the Human RNA Guanylyltransferase and 5'-Phosphatase
To be Published,
Experimental method
X-RAY DIFFRACTION (1.6 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.212101.9%5.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2c46
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Molmil generated image of 2c46
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Molmil generated image of 2c46
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More Biological unit images

Molmil generated image of 2c46
no rotation
Molmil generated image of 2c46
rotated about x axis by 90°
Molmil generated image of 2c46
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2c46.pdb3.gz [37.52 KB])
Coordinate files for Biological unit (2c46.pdb1.gz [133.98 KB])
Coordinate files for Biological unit (2c46.pdb4.gz [34.83 KB])
Coordinate files for Biological unit (2c46.pdb5.gz [33.03 KB])
Coordinate files for Biological unit (2c46.pdb2.gz [37.29 KB])