7CUM
Cryo-EM structure of human GABA(B) receptor bound to the antagonist CGP54626
Summary for 7CUM
Entry DOI | 10.2210/pdb7cum/pdb |
EMDB information | 30323 30324 30472 |
Descriptor | Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, (R)-(cyclohexylmethyl)[(2S)-3-{[(1S)-1-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropyl]phosphinic acid, ... (5 entities in total) |
Functional Keywords | gpcr, gaba, neurosignalling, signaling protein, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 187702.55 |
Authors | |
Primary citation | Kim, Y.,Jeong, E.,Jeong, J.H.,Kim, Y.,Cho, Y. Structural Basis for Activation of the Heterodimeric GABA B Receptor. J.Mol.Biol., 432:5966-5984, 2020 Cited by PubMed: 33058878DOI: 10.1016/j.jmb.2020.09.023 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.52 Å) |
Structure validation
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