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7L5L
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BU of 7l5l by Molmil
Crystal structure of the DiB-RM protein
分子名称: Lipocalin family protein, SULFATE ION
著者Bozhanova, N.G, Harp, J.M, Meiler, J.
登録日2020-12-22
公開日2021-10-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Computational redesign of a fluorogen activating protein with Rosetta.
Plos Comput.Biol., 17, 2021
7L5K
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Crystal structure of the DiB-RM protein
分子名称: DODECYL-BETA-D-MALTOSIDE, ISOPROPYL ALCOHOL, Lipocalin family protein, ...
著者Bozhanova, N.G, Harp, J.M, Meiler, J.
登録日2020-12-22
公開日2021-10-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Computational redesign of a fluorogen activating protein with Rosetta.
Plos Comput.Biol., 17, 2021
7LG4
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BU of 7lg4 by Molmil
Green fluorescent protein from Aequorea macrodactyla - amacGFP
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Bozhanova, N.G, Meiler, J.
登録日2021-01-19
公開日2021-01-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Heterogeneity of the GFP fitness landscape and data-driven protein design.
Elife, 11, 2022
6P9H
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BU of 6p9h by Molmil
Crystal structure of human anti staphylococcus aureus antibody STAU-281 Fab in complex with IsdB NEAT2 domain
分子名称: Human anti staphylococcus aureus antibody STAU-281 Fab heavy chain, Human anti staphylococcus aureus antibody STAU-281 Fab light chain, Iron-regulated heme-iron binding protein
著者Dong, J, Crowe, J.E.
登録日2019-06-10
公開日2020-06-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.003 Å)
主引用文献Human V H 1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis.
Mbio, 10, 2019
5WEQ
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BU of 5weq by Molmil
The crystal structure of a MR78 mutant
分子名称: MR78 mutant Fab heavy chain, MR78 mutant light chain
著者Dong, J, Williamson, L.E, Crowe, J.E.
登録日2017-07-10
公開日2018-04-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein.
Structure, 25, 2017
6WC6
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BU of 6wc6 by Molmil
Crystal structure of a truncated LSD1:CoREST in the presence of an LSD1-NT peptide
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LSD1-NT peptide, Lysine-specific histone demethylase 1A, ...
著者Reiter, N.J, Zeng, D, Senanayaka, D.
登録日2020-03-29
公開日2021-06-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Identification of structure and nucleosome binding within the N-terminus of lysine specific demethylase 1
To Be Published
4YAQ
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BU of 4yaq by Molmil
Crystal structure of a computationally optimized PG9 mutant
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PG9_N100FY Fab heavy chain, ...
著者Murrell, S, Julien, J.P, Wilson, I.A.
登録日2015-02-17
公開日2015-06-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.
J.Clin.Invest., 125, 2015
7U0C
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BU of 7u0c by Molmil
Crystal structure of broadly neutralizing antibody HEPC3.4
分子名称: HEPC3.4 Fab Heavy Chain, HEPC3.4 Fab Light Chain
著者Flyak, A.I, Bjorkman, P.J.
登録日2022-02-17
公開日2022-06-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals.
Nat Commun, 13, 2022
7U0B
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Crystal structure of broadly neutralizing antibody HEPC3.1
分子名称: HEPC3.1 Fab Heavy Chain, HEPC3.1 Fab Light Chain
著者Flyak, A.I, Bjorkman, P.J.
登録日2022-02-17
公開日2022-06-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals.
Nat Commun, 13, 2022
6P9J
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BU of 6p9j by Molmil
crystal structure of human anti staphylococcus aureus antibody STAU-229 Fab
分子名称: TRIS(HYDROXYETHYL)AMINOMETHANE, human anti staphylococcus aureus antibody STAU-229 Fab heavy chain, human anti staphylococcus aureus antibody STAU-229 Fab light chain
著者Dong, J, Crowe, J.E.
登録日2019-06-10
公開日2020-06-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Human V H 1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis.
Mbio, 10, 2019
6P9I
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BU of 6p9i by Molmil
crystal structure of human anti staphylococcus aureus antibody STAU-399 Fab
分子名称: human anti staphylococcus aureus antibody STAU-399 Fab heavy chain, human anti staphylococcus aureus antibody STAU-399 Fab light chain
著者Dong, J, Crowe, J.E.
登録日2019-06-10
公開日2020-06-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Human V H 1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis.
Mbio, 10, 2019
5JRP
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BU of 5jrp by Molmil
crystal structure of monoclonal antibody MR78 Fab
分子名称: SODIUM ION, marberg virus monoclonal antibody MR78 Fab heavy chain, marberg virus monoclonal antibody MR78 Fab light chain
著者Dong, J, Crowe, J.
登録日2016-05-06
公開日2017-11-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein.
Structure, 25, 2017
3TDM
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BU of 3tdm by Molmil
Computationally designed TIM-barrel protein, HalfFLR
分子名称: Computationally designed two-fold symmetric TIM-barrel protein, FLR (half molecule), PHOSPHATE ION
著者Harp, J.M, Fortenberry, C, Bowman, E, Profitt, W, Dorr, B, Mizoue, L.
登録日2011-08-11
公開日2011-11-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Exploring symmetry as an avenue to the computational design of large protein domains.
J.Am.Chem.Soc., 133, 2011
8DBZ
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BU of 8dbz by Molmil
CryoEM structure of Hantavirus ANDV Gn(H) protein complex with 2Fabs ANDV-5 and ANDV-34
分子名称: COV44-79 heavy chain constant domain, Fab Fc (L) KappaC, Fv (H) ANDV-34, ...
著者Binshtein, E, Crowe, J.E.
登録日2022-06-15
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Antigenic mapping and functional characterization of human new world hantavirus neutralizing antibodies.
Elife, 12, 2023
7SC0
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BU of 7sc0 by Molmil
CryoEM structure of the Caveolin-1 8S complex
分子名称: Caveolin-1
著者Porta, J.P, Ohi, M.D, Kenworthy, A.K, Karakas, E.
登録日2021-09-26
公開日2022-05-25
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Molecular architecture of the human caveolin-1 complex.
Sci Adv, 8, 2022
4ZV6
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BU of 4zv6 by Molmil
Crystal structure of the artificial alpharep-7 octarellinV.1 complex
分子名称: AlphaRep-7, Octarellin V.1
著者Figueroa, M, Sleutel, M, Urvoas, A, Valerio-Lepiniec, M, Minard, P, Martial, J.A, van de Weerdt, C.
登録日2015-05-18
公開日2016-05-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools.
J.Struct.Biol., 195, 2016
6NLE
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BU of 6nle by Molmil
X-ray structure of LeuT with V269 deletion
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Navratna, V, Yang, D, Gouaux, E.
登録日2019-01-08
公開日2020-01-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.615 Å)
主引用文献Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion inSLC6A3.
Proc.Natl.Acad.Sci.USA, 116, 2019
5BOP
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BU of 5bop by Molmil
Crystal structure of the artificial nanobody octarellinV.1 complex
分子名称: Nanobody, Octarellin V.1
著者Figueroa, M, Sleutel, M, Pardon, E, Steyaert, J, Martial, J.A, van de Weerdt, C.
登録日2015-05-27
公開日2016-05-25
最終更新日2016-06-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools.
J.Struct.Biol., 195, 2016
4HFW
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BU of 4hfw by Molmil
Anti Rotavirus Antibody
分子名称: 6-26 Fab Heavy chain, 6-26 Fab Light chain, SULFATE ION
著者Spiller, B.W, Aiyegbo, M, Crowe, J.E.
登録日2012-10-05
公開日2013-05-29
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Human Rotavirus VP6-Specific Antibodies Mediate Intracellular Neutralization by Binding to a Quaternary Structure in the Transcriptional Pore.
Plos One, 8, 2013
4GSD
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BU of 4gsd by Molmil
H5.3 Fab Structure
分子名称: H5.3 Fab Heavy Chain, H5.3 Fab Light Chain
著者Spiller, B.W, Winarski, K.L.
登録日2012-08-27
公開日2013-08-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses.
J.Clin.Invest., 123, 2013
5ITB
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BU of 5itb by Molmil
Crystal structure of the anti-RSV F Fab 14N4
分子名称: anti-RSV F Fab 14N4 Heavy chain, anti-RSV F Fab 14N4 Light chain
著者Mousa, J.J, Crowe, J.E.
登録日2016-03-16
公開日2016-10-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J3D
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BU of 5j3d by Molmil
Crystal structure of human Fab 14N4 in complex with post-fusion RSV F
分子名称: 14N4 heavy chain, 14N4 light chain, Fusion glycoprotein F0
著者Mousa, J.J, Crowe, J.E.
登録日2016-03-30
公開日2016-10-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.077 Å)
主引用文献Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
7LQK
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BU of 7lqk by Molmil
Crystal structure of the R375A mutant of LeuT
分子名称: ALANINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ...
著者Font, J, Aguilar, J, Galli, A, Ryan, R.
登録日2021-02-13
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia.
Elife, 10, 2021
7LQJ
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BU of 7lqj by Molmil
Crystal structure of LeuT bound to L-Alanine
分子名称: ALANINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ...
著者Font, J, Aguilar, J, Galli, A, Ryan, R.
登録日2021-02-13
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.144 Å)
主引用文献Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia.
Elife, 10, 2021
7LQL
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BU of 7lql by Molmil
Crystal structure of the R375D mutant of LeuT
分子名称: ALANINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ...
著者Font, J, Aguilar, J, Galli, A, Ryan, R.
登録日2021-02-13
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia.
Elife, 10, 2021

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