Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
3I9N
DownloadVisualize
BU of 3i9n by Molmil
Crystal structure of human CD38 complexed with an analog ribo-2'F-ADP ribose
分子名称: ADP-ribosyl cyclase 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4S)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate
著者Liu, Q, Graeff, R, Kriksunov, I.A, Jiang, H, Zhang, B, Oppenheimer, N, Lin, H, Potter, B.V.L, Lee, H.C, Hao, Q.
登録日2009-07-12
公開日2009-07-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase
J.Biol.Chem., 284, 2009
3I9K
DownloadVisualize
BU of 3i9k by Molmil
Crystal structure of ADP ribosyl cyclase complexed with substrate NAD
分子名称: ADP-ribosyl cyclase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Liu, Q, Graeff, R, Kriksunov, I.A, Jiang, H, Zhang, B, Oppenheimer, N, Lin, H, Potter, B.V.L, Lee, H.C, Hao, Q.
登録日2009-07-12
公開日2009-07-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase
J.Biol.Chem., 284, 2009
3I9M
DownloadVisualize
BU of 3i9m by Molmil
Crystal structure of human CD38 complexed with an analog ara-2'F-ADPR
分子名称: ADP-ribosyl cyclase 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4R)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate
著者Liu, Q, Graeff, R, Kriksunov, I.A, Jiang, H, Zhang, B, Oppenheimer, N, Lin, H, Potter, B.V.L, Lee, H.C, Hao, Q.
登録日2009-07-12
公開日2009-07-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase
J.Biol.Chem., 284, 2009
3I9O
DownloadVisualize
BU of 3i9o by Molmil
Crystal structure of ADP ribosyl cyclase complexed with ribo-2'F-ADP ribose
分子名称: ADP-ribosyl cyclase, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4S)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate
著者Graeff, R, Liu, Q, Kriksunov, I.A, Kotaka, M, Oppenheimer, N, Hao, Q, Lee, H.C.
登録日2009-07-12
公開日2009-07-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mechanism of cyclizing NAD to cyclic ADP-ribose by ADP-ribosyl cyclase and CD38
J.Biol.Chem., 284, 2009
3I9J
DownloadVisualize
BU of 3i9j by Molmil
Crystal structure of ADP ribosyl cyclase complexed with a substrate analog and a product nicotinamide
分子名称: ADP-ribosyl cyclase, NICOTINAMIDE, Nicotinamide 2-fluoro-adenine dinucleotide, ...
著者Liu, Q, Graeff, R, Kriksunov, I.A, Jiang, H, Zhang, B, Oppenheimer, N, Lin, H, Potter, B.V.L, Lee, H.C, Hao, Q.
登録日2009-07-12
公開日2009-07-28
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase
J.Biol.Chem., 284, 2009
3I9L
DownloadVisualize
BU of 3i9l by Molmil
Crystal structure of ADP ribosyl cyclase complexed with N1-cIDPR
分子名称: ADP-ribosyl cyclase, N1-CYCLIC INOSINE 5'-DIPHOSPHORIBOSE
著者Liu, Q, Graeff, R, Kriksunov, I.A, Jiang, H, Zhang, B, Oppenheimer, N, Lin, H, Potter, B.V.L, Lee, H.C, Hao, Q.
登録日2009-07-12
公開日2009-07-28
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase
J.Biol.Chem., 284, 2009
3ROP
DownloadVisualize
BU of 3rop by Molmil
Crystal structure of human CD38 in complex with compound CZ-50b
分子名称: 2-deoxy-2-fluoro-5-O-phosphono-alpha-D-ribofuranose, ADP-ribosyl cyclase 1, NICOTINAMIDE
著者Zhang, H, Lee, H.C, Hao, Q.
登録日2011-04-26
公開日2011-12-28
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Catalysis-based inhibitors of the calcium signaling function of CD38.
Biochemistry, 51, 2012
3RAJ
DownloadVisualize
BU of 3raj by Molmil
Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7
分子名称: ADP-ribosyl cyclase 1, heavy chain of the Fab fragment of antibody HB7, light chain of the Fab fragment of antibody HB7
著者Zhang, H, Lee, H.C, Hao, Q.
登録日2011-03-28
公開日2011-04-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.044 Å)
主引用文献Engineering a novel cytosolic form of CD38 for cyclic ADP-ribose dependent signaling
To be Published
3ROK
DownloadVisualize
BU of 3rok by Molmil
Crystal structure of human CD38 in complex with compound CZ-27
分子名称: 5-O-[(S)-butoxy(hydroxy)phosphoryl]-2-deoxy-2-fluoro-alpha-D-arabinofuranose, ADP-ribosyl cyclase 1
著者Zhang, H, Lee, H.C, Hao, Q.
登録日2011-04-26
公開日2011-12-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Catalysis-based inhibitors of the calcium signaling function of CD38.
Biochemistry, 51, 2012
3ROQ
DownloadVisualize
BU of 3roq by Molmil
Crystal structure of human CD38 in complex with compound CZ-46
分子名称: (2R,3R,4S,5S)-4-fluoro-3,5-dihydroxytetrahydrofuran-2-yl 2-phenylethyl hydrogen (S)-phosphate, ADP-ribosyl cyclase 1
著者Zhang, H, Lee, H.C, Hao, Q.
登録日2011-04-26
公開日2011-12-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Catalysis-based inhibitors of the calcium signaling function of CD38.
Biochemistry, 51, 2012
3ROM
DownloadVisualize
BU of 3rom by Molmil
Crystal structure of human CD38 in complex with compound CZ-48
分子名称: 2-deoxy-2-fluoro-5-O-thiophosphono-alpha-D-arabinofuranose, ADP-ribosyl cyclase 1
著者Zhang, H, Lee, H.C, Hao, Q.
登録日2011-04-26
公開日2011-12-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Catalysis-based inhibitors of the calcium signaling function of CD38.
Biochemistry, 51, 2012
3OFS
DownloadVisualize
BU of 3ofs by Molmil
Dynamic conformations of the CD38-mediated NAD cyclization captured using multi-copy crystallography
分子名称: ADP-ribosyl cyclase 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4R)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate
著者Zhang, H, Lee, H.C, Hao, Q.
登録日2010-08-16
公開日2010-12-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dynamic Conformations of the CD38-Mediated NAD Cyclization Captured in a Single Crystal
J.Mol.Biol., 405, 2011
2O3U
DownloadVisualize
BU of 2o3u by Molmil
Structural Basis for Formation and Hydrolysis of Calcium Messenger Cyclic ADP-ribose by Human CD38
分子名称: 3-(AMINOCARBONYL)-1-[(2R,3R,4S,5R)-5-({[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(2-AMINO-6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)-3,4-DIHYD ROXYTETRAHYDROFURAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]OXY}METHYL)-3,4-DIHYDROXYTETRAHYDROFURAN-2- YL]PYRIDINIUM, ADP-ribosyl cyclase 1
著者Liu, Q, Kriksunov, I.A, Graeff, R, Lee, H.C, Hao, Q.
登録日2006-12-01
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38
J.Biol.Chem., 282, 2007
2O3S
DownloadVisualize
BU of 2o3s by Molmil
Structural Basis for Formation and Hydrolysis of Calcium Messenger Cyclic ADP-ribose by Human CD38
分子名称: ADP-ribosyl cyclase 1, CYCLIC ADENOSINE DIPHOSPHATE-RIBOSE
著者Liu, Q, Kriksunov, I.A, Graeff, R, Lee, H.C, Hao, Q.
登録日2006-12-01
公開日2006-12-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38
J.Biol.Chem., 282, 2007
2O3T
DownloadVisualize
BU of 2o3t by Molmil
Structural Basis for Formation and Hydrolysis of Calcium Messenger Cyclic ADP-ribose by Human CD38
分子名称: ADP-ribosyl cyclase 1, CYCLIC GUANOSINE DIPHOSPHATE-RIBOSE
著者Liu, Q, Kriksunov, I.A, Graeff, R, Lee, H.C, Hao, Q.
登録日2006-12-01
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38
J.Biol.Chem., 282, 2007
2O3Q
DownloadVisualize
BU of 2o3q by Molmil
Structural Basis for Formation and Hydrolysis of Calcium Messenger Cyclic ADP-ribose by Human CD38
分子名称: ADP-ribosyl cyclase 1, CYCLIC ADENOSINE DIPHOSPHATE-RIBOSE
著者Liu, Q, Kriksunov, I.A, Graeff, R, Lee, H.C, Hao, Q.
登録日2006-12-01
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38
J.Biol.Chem., 282, 2007
2O3R
DownloadVisualize
BU of 2o3r by Molmil
Structural Basis for Formation and Hydrolysis of Calcium Messenger Cyclic ADP-ribose by Human CD38
分子名称: ADP-ribosyl cyclase 1, CYCLIC ADENOSINE DIPHOSPHATE-RIBOSE
著者Liu, Q, Kriksunov, I.A, Graeff, R, Lee, H.C, Hao, Q.
登録日2006-12-01
公開日2006-12-12
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38
J.Biol.Chem., 282, 2007
2PGL
DownloadVisualize
BU of 2pgl by Molmil
Catalysis associated conformational changes revealed by human CD38 complexed with a non-hydrolyzable substrate analog
分子名称: ADP-ribosyl cyclase 1, N1-CYCLIC INOSINE 5'-DIPHOSPHORIBOSE
著者Liu, Q, Kriksunov, I.A, Moreau, C, Graeff, R, Potter, B.V.L, Lee, H.C, Hao, Q.
登録日2007-04-09
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Catalysis-associated Conformational Changes Revealed by Human CD38 Complexed with a Non-hydrolyzable Substrate Analog
J.Biol.Chem., 282, 2007
2PGJ
DownloadVisualize
BU of 2pgj by Molmil
Catalysis associated conformational changes revealed by human cd38 complexed with a non-hydrolyzable substrate analog
分子名称: ADP-ribosyl cyclase 1, N1-CYCLIC INOSINE 5'-DIPHOSPHORIBOSE
著者Liu, Q, Kriksunov, I.A, Moreau, C, Graeff, R, Potter, B.V.L, Lee, H.C, Hao, Q.
登録日2007-04-09
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Catalysis-associated Conformational Changes Revealed by Human CD38 Complexed with a Non-hydrolyzable Substrate Analog
J.Biol.Chem., 282, 2007
2HCT
DownloadVisualize
BU of 2hct by Molmil
Acidic residues at the active sites of CD38 and ADP-ribosyl cyclase determine NAAPD synthesis and hydrolysis activities
分子名称: ADP-ribosyl cyclase 1, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE
著者Liu, Q, Kriksunov, I.A, Hao, Q, Graeff, R, Lee, H.C.
登録日2006-06-18
公開日2006-08-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Acidic residues at the active sites of CD38 and ADP-ribosyl cyclase determine nicotinic acid adenine dinucleotide phosphate (NAADP) synthesis and hydrolysis activities.
J.Biol.Chem., 281, 2006
2I66
DownloadVisualize
BU of 2i66 by Molmil
Structural Basis for the Mechanistic Understanding Human CD38 Controlled Multiple Catalysis
分子名称: ADP-ribosyl cyclase 1, [(2R,3R,4R,5R)-5-(2-AMINO-6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4R,5S)-3,4,5-TRIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE, [(2R,3R,4R,5R)-5-(2-AMINO-6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE
著者Liu, Q, Kriksunov, I.A, Graeff, R, Munshi, C, Lee, H.C, Hao, Q.
登録日2006-08-28
公開日2006-09-05
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis.
J.Biol.Chem., 281, 2006
2I65
DownloadVisualize
BU of 2i65 by Molmil
Structural Basis for the Mechanistic Understanding Human CD38 Controlled Multiple Catalysis
分子名称: ADP-ribosyl cyclase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Liu, Q, Kriksunov, I.A, Graeff, R, Munshi, C, Lee, H.C, Hao, Q.
登録日2006-08-28
公開日2006-09-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis.
J.Biol.Chem., 281, 2006
2I67
DownloadVisualize
BU of 2i67 by Molmil
Structural Basis for the Mechanistic Understanding Human CD38 Controlled Multiple Catalysis
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, ADP-ribosyl cyclase 1
著者Liu, Q, Kriksunov, I.A, Graeff, R, Munshi, C, Lee, H.C, Hao, Q.
登録日2006-08-28
公開日2006-09-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis.
J.Biol.Chem., 281, 2006
3U4H
DownloadVisualize
BU of 3u4h by Molmil
CD38 structure-based inhibitor design using the N1-cyclic inosine 5'-diphosphate ribose template
分子名称: 8-Amino-N1-Cyclic Inosine 5'-Diphosphoribose, ADP-ribosyl cyclase 1
著者Liu, Q, Hao, Q, Lee, H.C, Graeff, R.
登録日2011-10-08
公開日2012-10-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.878 Å)
主引用文献CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5'-Diphosphate Ribose Template
Plos One, 8, 2013
3U4I
DownloadVisualize
BU of 3u4i by Molmil
CD38 structure-based inhibitor design using the N1-cyclic inosine 5'-diphosphate ribose template
分子名称: ADP-ribosyl cyclase 1, Cyclic adenosine 5'-diphosphocarbocyclic ribose
著者Liu, Q, Hao, Q, Lee, H.C, Graeff, R.
登録日2011-10-08
公開日2012-10-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.118 Å)
主引用文献CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5'-Diphosphate Ribose Template
Plos One, 8, 2013

226707

件を2024-10-30に公開中

PDB statisticsPDBj update infoContact PDBjnumon