Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
2J4H
DownloadVisualize
BU of 2j4h by Molmil
Crystal structure of a H121A Escherichia coli dCTP deaminase mutant enzyme
分子名称: DEOXYCYTIDINE DIPHOSPHATE, DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, MAGNESIUM ION
著者Johansson, E, Thymark, M, Bynck, J.H, Fanoe, M, Larsen, S, Willemoes, M.
登録日2006-08-31
公開日2007-08-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Regulation of Dctp Deaminase from Escherichia Coli by Nonallosteric Dttp Binding to an Inactive Form of the Enzyme
FEBS J., 274, 2007
5J4Q
DownloadVisualize
BU of 5j4q by Molmil
alpha-chymotrypsin from bovine pancreas in complex with Bowman-Birk inhibitor from soybean
分子名称: Bowman-Birk type proteinase inhibitor, Chymotrypsinogen A
著者Johansson, E, Tornoee, C.W.
登録日2016-04-01
公開日2017-04-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Divergent Protein Synthesis of Bowman-Birk Protease Inhibitors, their Hydrodynamic Behavior and Co-crystallization with alpha-Chymotrypsin
Synlett, 2017
7BG0
DownloadVisualize
BU of 7bg0 by Molmil
Fusion of MBP and the backbone of the long-acting amylin analog AM833.
分子名称: Maltose/maltodextrin-binding periplasmic protein,Islet amyloid polypeptide, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Johansson, E.
登録日2021-01-05
公開日2021-08-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Development of Cagrilintide, a Long-Acting Amylin Analogue.
J.Med.Chem., 64, 2021
8CHE
DownloadVisualize
BU of 8che by Molmil
TLT-1 binding Fab of the bispecific antibody HMB-001 in complex with the TLT-1 stalk peptide
分子名称: Fab heavy chain, Fab light chain, Trem-like transcript 1 protein
著者Johansson, E, Schluckebier, G.
登録日2023-02-07
公開日2023-12-27
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献HMB-001: A Novel Bispecific Antibody Accumulating and Targeting Endogenous FVIIa to Activated Platelets for Subcutaneous Prophylaxis in Multiple Bleeding Disorders Including Glanzmann Thrombasthenia.
To Be Published
8OL9
DownloadVisualize
BU of 8ol9 by Molmil
Anti-FIXa Fab in complex with human des-(Gla-EGF1) FIXa
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Coagulation factor IX heavy chain, ...
著者Johansson, E, Svensson, L.A.
登録日2023-03-30
公開日2023-07-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Computational design of N-linked glycans for high throughput epitope profiling.
Protein Sci., 32, 2023
8ONK
DownloadVisualize
BU of 8onk by Molmil
Human insulin in complex with the analytical antibody S1 Fab and the analytical antibody HUI-001 Fab
分子名称: Heavy chain of analytical antibody HUI-001 Fab, Heavy chain of analytical antibody S1 Fab, Insulin A chain, ...
著者Johansson, E.
登録日2023-04-03
公開日2024-04-10
実験手法X-RAY DIFFRACTION (3.403 Å)
主引用文献Macromolecular structure of insulin and IgE clonality impacts IgE-mediated activation of sensitized basophils
To Be Published
8ONI
DownloadVisualize
BU of 8oni by Molmil
Human insulin in complex with the analytical antibody S1 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of analytical antibody S1 Fab, Insulin A chain, ...
著者Johansson, E.
登録日2023-04-03
公開日2024-04-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Macromolecular structure of insulin and IgE clonality impacts IgE-mediated activation of sensitized basophils
To Be Published
8PI4
DownloadVisualize
BU of 8pi4 by Molmil
Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in dimer (T2) conformation
分子名称: Insulin B chain,Insulin A chain
著者Johansson, E, Schluckebier, G.
登録日2023-06-21
公開日2023-11-08
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 42, 2024
8PI6
DownloadVisualize
BU of 8pi6 by Molmil
Crystal structure of the monomeric zinc free human insulin A22K, B3E, B26E, B29R, desB30 precursor with a Ser-Glu-Asp-Trp-Trp-Arg C-peptide and a Glu-Glu-Gly-Glu-Pro-Arg N-terminal extension
分子名称: Insulin B chain,Insulin A chain
著者Johansson, E, Schluckebier, G.
登録日2023-06-21
公開日2023-11-08
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 42, 2024
8PI5
DownloadVisualize
BU of 8pi5 by Molmil
Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in hexamer (T3R3) conformation
分子名称: CHLORIDE ION, Insulin B chain,Insulin A chain, RESORCINOL, ...
著者Johansson, E, Schluckebier, G.
登録日2023-06-21
公開日2023-11-08
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 42, 2024
7AHU
DownloadVisualize
BU of 7ahu by Molmil
Anti-FX Fab of mim8 in complex with human FXa
分子名称: Anti-FX Fab of mim8 heavy chain, Anti-FX Fab of mim8 light chain, CALCIUM ION, ...
著者Johansson, E.
登録日2020-09-25
公開日2021-07-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A factor VIIIa-mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice.
Blood, 138, 2021
7AHV
DownloadVisualize
BU of 7ahv by Molmil
Anti-FIXa Fab of mim8 in complex with human FIXa
分子名称: CALCIUM ION, Coagulation factor IX, L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide, ...
著者Johansson, E.
登録日2020-09-25
公開日2021-07-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献A factor VIIIa-mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice.
Blood, 138, 2021
6S4J
DownloadVisualize
BU of 6s4j by Molmil
Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB27, desB30 human insulin
分子名称: IMIDAZOLE, Insulin, KUT [2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]
著者Johansson, E.
登録日2019-06-28
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Molecular engineering of safe and efficacious oral basal insulin.
Nat Commun, 11, 2020
6S4I
DownloadVisualize
BU of 6s4i by Molmil
Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB30 human insulin
分子名称: Insulin, NITRATE ION
著者Johansson, E.
登録日2019-06-28
公開日2020-07-15
最終更新日2020-08-12
実験手法X-RAY DIFFRACTION (1.511 Å)
主引用文献Molecular engineering of safe and efficacious oral basal insulin.
Nat Commun, 11, 2020
7NHU
DownloadVisualize
BU of 7nhu by Molmil
Crystal structure of desB30 insulin produced by cell free protein synthesis
分子名称: Insulin
著者Johansson, E.
登録日2021-02-11
公開日2021-06-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Cell free protein synthesis versus yeast expression - A comparison using insulin as a model protein.
Protein Expr.Purif., 186, 2021
5J4S
DownloadVisualize
BU of 5j4s by Molmil
alpha-chymotrypsin from bovine pancreas in complex with a modified Bowman-Birk inhibitor from soybean
分子名称: Bowman-Birk type proteinase inhibitor, Chymotrypsinogen A
著者Johansson, E, Tornoee, C.W.
登録日2016-04-01
公開日2017-04-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献Divergent Protein Synthesis of Bowman-Birk Protease Inhibitors, their Hydrodynamic Behavior and Co-crystallization with alpha-Chymotrypsin
Synlett, 2017
1FTD
DownloadVisualize
BU of 1ftd by Molmil
5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'-SYMMETRIC BIS-BENZIMIDAZOLE COMPLEX
分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION, [3-(4-{2'-[4-(3-DIMETHYLAMINO-PROPOXY)-PHENYL]-3H,3'H-[5,5']BIBENZOIMIDAZOLYL-2-YL}-PHENOXY)-PROPYL]-DIMETHYL-AMINE
著者Mann, J, Baron, A, Opoku-Boahen, Y, Johansson, E, Parkinson, G, Kelland, L.R, Neidle, S.
登録日2000-09-12
公開日2001-02-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A new class of symmetric bisbenzimidazole-based DNA minor groove-binding agents showing antitumor activity.
J.Med.Chem., 44, 2001
4M8O
DownloadVisualize
BU of 4m8o by Molmil
TERNARY COMPLEX OF DNA POLYMERASE EPSILON WITH AN INCOMING dATP
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2-AMINOETHANESULFONIC ACID, CHLORIDE ION, ...
著者Sauer-Eriksson, A.E, Hogg, M, Osterman, P, Johansson, E.
登録日2013-08-13
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for processive DNA synthesis by yeast DNA polymerase epsilon.
Nat.Struct.Mol.Biol., 21, 2014
8B67
DownloadVisualize
BU of 8b67 by Molmil
The crystal structure of M644G variant of DNA Pol Epsilon containing CTP in the polymerase active site
分子名称: ACETATE ION, CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, ...
著者Parkash, V, Johansson, E.
登録日2022-09-26
公開日2023-10-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B79
DownloadVisualize
BU of 8b79 by Molmil
The crystal structure of M644G variant of DNA Pol Epsilon containing UTP in the polymerase active site
分子名称: ACETATE ION, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ...
著者Parkash, V, Johansson, E.
登録日2022-09-29
公開日2023-10-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B7E
DownloadVisualize
BU of 8b7e by Molmil
The crystal structure of N828V variant of DNA Pol Epsilon containing UTP in the polymerase active site
分子名称: CALCIUM ION, DNA polymerase epsilon catalytic subunit A, GLYCEROL, ...
著者Parkash, V, Johansson, E.
登録日2022-09-29
公開日2023-10-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B6K
DownloadVisualize
BU of 8b6k by Molmil
The crystal structure of M644G variant of DNA Pol Epsilon containing dCTP in the polymerase active site
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ...
著者Parkash, V, Johansson, E.
登録日2022-09-27
公開日2023-10-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B77
DownloadVisualize
BU of 8b77 by Molmil
The crystal structure of N828V variant of DNA Pol Epsilon containing dATP in the polymerase active site
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ...
著者Parkash, V, Johansson, E.
登録日2022-09-29
公開日2023-10-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B76
DownloadVisualize
BU of 8b76 by Molmil
The crystal structure of M644G variant of DNA Pol Epsilon containing dTTP in the polymerase active site
分子名称: ACETATE ION, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ...
著者Parkash, V, Johansson, E.
登録日2022-09-28
公開日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8CN9
DownloadVisualize
BU of 8cn9 by Molmil
Factor VII binding Fab of the bispecific antibody HMB-001 in complex with Factor VII
分子名称: CALCIUM ION, CESIUM ION, Coagulation factor VII, ...
著者Schluckebier, G, Johansson, E.
登録日2023-02-22
公開日2023-12-27
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献A bispecific antibody approach for the potential prophylactic treatment of inherited bleeding disorders
Nat Cardiovasc Res, 2023

221051

件を2024-06-12に公開中

PDB statisticsPDBj update infoContact PDBjnumon