7BG0
Fusion of MBP and the backbone of the long-acting amylin analog AM833.
Summary for 7BG0
Entry DOI | 10.2210/pdb7bg0/pdb |
Related PRD ID | PRD_900001 |
Descriptor | Maltose/maltodextrin-binding periplasmic protein,Islet amyloid polypeptide, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose (2 entities in total) |
Functional Keywords | amylin, am833, cagrilintide, hormone |
Biological source | Escherichia coli (strain K12) More |
Total number of polymer chains | 4 |
Total formula weight | 178665.78 |
Authors | Johansson, E. (deposition date: 2021-01-05, release date: 2021-08-04, Last modification date: 2024-01-31) |
Primary citation | Kruse, T.,Hansen, J.L.,Dahl, K.,Schaffer, L.,Sensfuss, U.,Poulsen, C.,Schlein, M.,Hansen, A.M.K.,Jeppesen, C.B.,Dornonville de la Cour, C.,Clausen, T.R.,Johansson, E.,Fulle, S.,Skyggebjerg, R.B.,Raun, K. Development of Cagrilintide, a Long-Acting Amylin Analogue. J.Med.Chem., 64:11183-11194, 2021 Cited by PubMed: 34288673DOI: 10.1021/acs.jmedchem.1c00565 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.89 Å) |
Structure validation
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