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7BG0

Fusion of MBP and the backbone of the long-acting amylin analog AM833.

Summary for 7BG0
Entry DOI10.2210/pdb7bg0/pdb
Related PRD IDPRD_900001
DescriptorMaltose/maltodextrin-binding periplasmic protein,Islet amyloid polypeptide, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose (2 entities in total)
Functional Keywordsamylin, am833, cagrilintide, hormone
Biological sourceEscherichia coli (strain K12)
More
Total number of polymer chains4
Total formula weight178665.78
Authors
Johansson, E. (deposition date: 2021-01-05, release date: 2021-08-04, Last modification date: 2024-01-31)
Primary citationKruse, T.,Hansen, J.L.,Dahl, K.,Schaffer, L.,Sensfuss, U.,Poulsen, C.,Schlein, M.,Hansen, A.M.K.,Jeppesen, C.B.,Dornonville de la Cour, C.,Clausen, T.R.,Johansson, E.,Fulle, S.,Skyggebjerg, R.B.,Raun, K.
Development of Cagrilintide, a Long-Acting Amylin Analogue.
J.Med.Chem., 64:11183-11194, 2021
Cited by
PubMed: 34288673
DOI: 10.1021/acs.jmedchem.1c00565
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.89 Å)
Structure validation

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