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7ZAY
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BU of 7zay by Molmil
Human heparan sulfate polymerase complex EXT1-EXT2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Exostosin-1, Exostosin-2, ...
著者Leisico, F, Omeiri, J, Hons, M, Schoehn, G, Lortat-Jacob, H, Wild, R.
登録日2022-03-23
公開日2022-12-07
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure of the human heparan sulfate polymerase complex EXT1-EXT2.
Nat Commun, 13, 2022
8AXV
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BU of 8axv by Molmil
Structure of an open form of CHIKV nsP1 capping pores
分子名称: 2-amino-7-methyl-1,7-dihydro-6H-purin-6-one, ZINC ION, mRNA-capping enzyme nsP1
著者Reguera, J, Jones, R, Hons, M.
登録日2022-09-01
公開日2023-03-29
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores.
Proc.Natl.Acad.Sci.USA, 120, 2023
8AOX
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BU of 8aox by Molmil
CryoEM structure of the Chikungunya virus nsP1 capping pores in complex with SAM
分子名称: S-ADENOSYLMETHIONINE, ZINC ION, mRNA-capping enzyme nsP1
著者Jones, R, Hons, M, Reguera, J.
登録日2022-08-08
公開日2023-03-29
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores.
Proc.Natl.Acad.Sci.USA, 120, 2023
8AOW
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BU of 8aow by Molmil
CryoEM structure of the Chikungunya virus nsP1 capping pores in complex with m7GTP and SAH ligands
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Jones, R, Hons, M, Reguera, J.
登録日2022-08-08
公開日2023-03-29
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores.
Proc.Natl.Acad.Sci.USA, 120, 2023
8PHZ
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BU of 8phz by Molmil
Helical reconstruction of CHIKV nsP3 helical scaffolds
分子名称: Non-structural protein 3, ZINC ION
著者Reguera, J, Hons, M, Zimberger, C, Ptchelkine, D, Jones, R, Desfosses, A.
登録日2023-06-20
公開日2024-08-14
実験手法ELECTRON MICROSCOPY (2.35 Å)
主引用文献The alphavirus nsP3 protein forms helical tubular scaffolds important for viral replication and particle assembly
To be published
8PK7
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BU of 8pk7 by Molmil
Helical reconstruction of CHIKV nsP3 helical scaffolds
分子名称: Non-structural protein 3, ZINC ION
著者Reguera, J, Hons, M, Zimberger, C, Ptchelkine, D, Jones, R, Desfosses, A.
登録日2023-06-25
公開日2024-08-14
実験手法ELECTRON MICROSCOPY (2.52 Å)
主引用文献The alphavirus nsP3 protein forms helical tubular scaffolds important for viral replication and particle assembly
To Be Published
6UPH
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BU of 6uph by Molmil
Structure of a Yeast Centromeric Nucleosome at 2.7 Angstrom resolution
分子名称: DNA (119-MER), Histone H2A, Histone H2B.1, ...
著者Migl, D, Kschonsak, M, Arthur, C.P, Khin, Y, Harrison, S.C, Ciferri, C, Dimitrova, Y.N.
登録日2019-10-17
公開日2019-11-06
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Cryoelectron Microscopy Structure of a Yeast Centromeric Nucleosome at 2.7 angstrom Resolution.
Structure, 28, 2020
6QJ4
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BU of 6qj4 by Molmil
Crystal structure of the C. thermophilum condensin Ycs4-Brn1 subcomplex bound to the Smc4 ATPase head in complex with the C-terminal domain of Brn1
分子名称: Brn1, Condensin complex subunit 1,Condensin complex subunit 1,Condensin complex subunit 1, Condensin complex subunit 2, ...
著者Hassler, M, Haering, C.H, Kschonsak, M.
登録日2019-01-22
公開日2019-07-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (5.8 Å)
主引用文献Structural Basis of an Asymmetric Condensin ATPase Cycle.
Mol.Cell, 74, 2019
6QJ3
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BU of 6qj3 by Molmil
Crystal structure of the C. thermophilum condensin Ycs4-Brn1 subcomplex
分子名称: Brn1, Condensin complex subunit 1,Condensin complex subunit 1,Ycs4, Condensin complex subunit 2
著者Hassler, M, Haering, C.H, Kschonsak, M.
登録日2019-01-22
公開日2019-07-03
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural Basis of an Asymmetric Condensin ATPase Cycle.
Mol.Cell, 74, 2019
5FRR
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BU of 5frr by Molmil
Structure of the Pds5-Scc1 complex and implications for cohesin function
分子名称: SISTER CHROMATID COHESION PROTEIN PDS5
著者Muir, K.W, Kschonsak, M, Li, Y, Metz, J, Haering, C.H, Panne, D.
登録日2015-12-22
公開日2016-03-02
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (5.8 Å)
主引用文献Structure of the Pds5-Scc1 Complex and Implications for Cohesin Function
Cell Rep., 14, 2016
5FRS
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BU of 5frs by Molmil
Structure of the Pds5-Scc1 complex and implications for cohesin function
分子名称: SISTER CHROMATID COHESION PROTEIN 1, SISTER CHROMATID COHESION PROTEIN PDS5
著者Muir, K.W, Kschonsak, M, Li, Y, Metz, J, Haering, C.H, Panne, D.
登録日2015-12-22
公開日2016-03-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (4.073 Å)
主引用文献Structure of the Pds5-Scc1 Complex and Implications for Cohesin Function
Cell Rep., 14, 2016
5FRP
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BU of 5frp by Molmil
Structure of the Pds5-Scc1 complex and implications for cohesin function
分子名称: MCD1-LIKE PROTEIN, SISTER CHROMATID COHESION PROTEIN PDS5
著者Muir, K.W, Kschonsak, M, Li, Y, Metz, J, Haering, C.H, Panne, D.
登録日2015-12-21
公開日2016-03-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.895 Å)
主引用文献Structure of the Pds5-Scc1 Complex and Implications for Cohesin Function
Cell Rep., 14, 2016
7TJ8
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BU of 7tj8 by Molmil
Cryo-EM structure of the human Nax channel in complex with beta3 solved in nanodiscs
分子名称: (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Noland, C.L, Kschonsak, M, Ciferri, C, Payandeh, J.
登録日2022-01-14
公開日2022-03-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure-guided unlocking of Na X reveals a non-selective tetrodotoxin-sensitive cation channel.
Nat Commun, 13, 2022
7TJ9
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BU of 7tj9 by Molmil
Cryo-EM structure of the human Nax channel in complex with beta3 solved in GDN
分子名称: (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Noland, C.L, Kschonsak, M, Ciferri, C, Payandeh, J.
登録日2022-01-14
公開日2022-03-30
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure-guided unlocking of Na X reveals a non-selective tetrodotoxin-sensitive cation channel.
Nat Commun, 13, 2022
7QG0
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BU of 7qg0 by Molmil
Inhibitor-induced hSARM1 duplex
分子名称: NAD(+) hydrolase SARM1
著者Zalk, R, Kahzma, T, Guez-Haddad, J.
登録日2021-12-07
公開日2022-12-21
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献A duplex structure of SARM1 octamers stabilized by a new inhibitor.
Cell.Mol.Life Sci., 80, 2022
6RLP
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BU of 6rlp by Molmil
Cryo-EM reconstruction of TMV coat protein
分子名称: Capsid protein, RNA (5'-R(P*GP*AP*A)-3')
著者Kandiah, E, Effantin, G.
登録日2019-05-02
公開日2022-11-23
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献CM01: a facility for cryo-electron microscopy at the European Synchrotron.
Acta Crystallogr D Struct Biol, 75, 2019
6GFJ
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BU of 6gfj by Molmil
Structure of RIP2 CARD domain fused to crystallisable MBP tag
分子名称: Sugar ABC transporter substrate-binding protein,Receptor-interacting serine/threonine-protein kinase 2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Pellegrini, E, Cusack, S.
登録日2018-04-30
公開日2019-03-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献RIP2 filament formation is required for NOD2 dependent NF-kappa B signalling.
Nat Commun, 9, 2018
8P2L
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BU of 8p2l by Molmil
A CHIMERA construct containing human SARM1 ARM and SAM domains and C. elegans TIR domain.
分子名称: NAD(+) hydrolase SARM1,NAD(+) hydrolase tir-1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Isupov, M.N, Opatowsky, Y.
登録日2023-05-16
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans.
Cell Rep, 42, 2023
8P2M
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BU of 8p2m by Molmil
C. elegans TIR-1 protein.
分子名称: NAD(+) hydrolase tir-1
著者Isupov, M.N, Opatowsky, Y.
登録日2023-05-16
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (3.82 Å)
主引用文献Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans.
Cell Rep, 42, 2023
8AZA
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BU of 8aza by Molmil
Structure of RIP2K dimer bound to the XIAP BIR2 domain
分子名称: E3 ubiquitin-protein ligase XIAP, Receptor-interacting serine/threonine-protein kinase 2, ZINC ION
著者Pellegrini, E, Cusack, S.
登録日2022-09-05
公開日2022-10-26
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface.
Life Sci Alliance, 6, 2023
8QHC
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BU of 8qhc by Molmil
Cryo-EM structure of SidH from Legionella pneumophila in complex with LubX
分子名称: E3 ubiquitin--protein ligase, Elongation factor Tu, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Sharma, R, Adams, M, Bhogaraju, S.
登録日2023-09-07
公開日2023-10-11
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for the toxicity of Legionella pneumophila effector SidH.
Nat Commun, 14, 2023
8QFS
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BU of 8qfs by Molmil
Cryo-EM structure of SidH from Legionella pneumophila
分子名称: Elongation factor Tu, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Sharma, R, Weis, F, Bhogaraju, S.
登録日2023-09-04
公開日2023-10-11
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis for the toxicity of Legionella pneumophila effector SidH.
Nat Commun, 14, 2023
7QEN
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BU of 7qen by Molmil
S.c. Condensin core in DNA- and ATP-bound state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Condensin complex subunit 1, Condensin complex subunit 2, ...
著者Lecomte, L, Hassler, M, Haering, C, Eustermann, S.
登録日2021-12-03
公開日2022-06-15
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献A hold-and-feed mechanism drives directional DNA loop extrusion by condensin.
Science, 376, 2022
7QFW
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BU of 7qfw by Molmil
S.c. Condensin peripheral Ycg1 subcomplex bound to DNA
分子名称: Condensin complex subunit 2, Condensin complex subunit 3, Synthetic DNA ligand, ...
著者Lecomte, L, Hassler, M, Haering, C, Eustermann, S.
登録日2021-12-06
公開日2022-06-15
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献A hold-and-feed mechanism drives directional DNA loop extrusion by condensin.
Science, 376, 2022
6YVV
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BU of 6yvv by Molmil
Condensin complex from S.cerevisiae ATP-free apo bridged state
分子名称: Condensin complex subunit 1,Ycs4, Condensin complex subunit 2,Brn1, Structural maintenance of chromosomes protein 2,Structural maintenance of chromosomes protein 2, ...
著者Lee, B.-G, Cawood, C, Gutierrez-Escribano, P, Nakane, T, Merkel, F, Hassler, M, Haering, C.H, Aragon, L, Lowe, J.
登録日2020-04-28
公開日2020-07-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism.
Nat.Struct.Mol.Biol., 27, 2020

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