8TLD
 
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1I1R
 | | CRYSTAL STRUCTURE OF A CYTOKINE/RECEPTOR COMPLEX | | 分子名称: | INTERLEUKIN-6 RECEPTOR BETA CHAIN, VIRAL IL-6 | | 著者 | Chow, D, He, X, Snow, A.L, Rose-John, S, Garcia, K.C. | | 登録日 | 2001-02-02 | | 公開日 | 2001-03-28 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of an extracellular gp130 cytokine receptor signaling complex.
Science, 291, 2001
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5WB1
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5WB2
 | | US28 bound to engineered chemokine CX3CL1.35 and nanobodies | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHOLESTEROL, ... | | 著者 | Jude, K.M, Burg, J.S, Tsutsumi, N, Miles, T.F, Garcia, K.C. | | 登録日 | 2017-06-27 | | 公開日 | 2018-06-13 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy.
Elife, 7, 2018
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4XL1
 | | Complex of Notch1 (EGF11-13) bound to Delta-like 4 (N-EGF1) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Luca, V.C, Jude, K.M, Garcia, K.C. | | 登録日 | 2015-01-13 | | 公開日 | 2015-03-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural biology. Structural basis for Notch1 engagement of Delta-like 4.
Science, 347, 2015
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4XLW
 | | Complex of Notch1 (EGF11-13) bound to Delta-like 4 (N-EGF2) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Delta-like protein, ... | | 著者 | Luca, V.C, Jude, K.M, Garcia, K.C. | | 登録日 | 2015-01-13 | | 公開日 | 2015-03-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.39 Å) | | 主引用文献 | Structural biology. Structural basis for Notch1 engagement of Delta-like 4.
Science, 347, 2015
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4XT3
 | | Structure of a viral GPCR bound to human chemokine CX3CL1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fractalkine, G-protein coupled receptor homolog US28, ... | | 著者 | Burg, J.S, Jude, K.M, Waghray, D, Garcia, K.C. | | 登録日 | 2015-01-22 | | 公開日 | 2015-03-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.801 Å) | | 主引用文献 | Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor.
Science, 347, 2015
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7N2P
 | | AS4.3-RNASEH2b-HLA*B27 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, AS4.3 T cell receptor beta chain, ... | | 著者 | Yang, X, Jude, K.M, Garcia, K.C. | | 登録日 | 2021-05-29 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Nature, 612, 2022
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7N2O
 | | AS4.2-YEIH-HLA*B27 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... | | 著者 | Yang, X, Jude, K.M, Garcia, K.C. | | 登録日 | 2021-05-29 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Nature, 612, 2022
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1U3H
 | | Crystal structure of mouse TCR 172.10 complexed with MHC class II I-Au molecule at 2.4 A | | 分子名称: | H-2 class II histocompatibility antigen, A-U alpha chain, A-U beta chain, ... | | 著者 | Maynard, J, Petersson, K, Wilson, D.H, Adams, E.J, Blondelle, S.E, Boulanger, M.J, Wilson, D.B, Garcia, K.C. | | 登録日 | 2004-07-21 | | 公開日 | 2005-05-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity
Immunity, 22, 2005
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1YK1
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1YK0
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1YPZ
 | | Immune receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | | 著者 | Adams, E.J, Garcia, K.C. | | 登録日 | 2005-01-31 | | 公開日 | 2005-04-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22.
Science, 308, 2005
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1Z92
 | | structure of interleukin-2 with its alpha receptor | | 分子名称: | Interleukin-2, Interleukin-2 receptor alpha chain | | 著者 | Rickert, M, Wang, X.Q, Goriatcheva, N, Boulanger, M.J, Garcia, K.C. | | 登録日 | 2005-03-31 | | 公開日 | 2005-06-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The structure of interleukin-2 complexed with its alpha receptor.
Science, 308, 2005
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2Z31
 | | Crystal structure of immune receptor complex | | 分子名称: | H-2 class II histocompatibility antigen, A-U alpha chain, A-U beta chain precursor, ... | | 著者 | Feng, D, Bond, C.J, Ely, L.K, Garcia, K.C. | | 登録日 | 2007-05-30 | | 公開日 | 2007-10-09 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'
Nat.Immunol., 8, 2007
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2Z35
 | | Crystal structure of immune receptor | | 分子名称: | T-cell receptor alpha-chain, T-cell receptor beta-chain | | 著者 | Feng, D, Bond, C.J, Ely, L.K, Garcia, K.C. | | 登録日 | 2007-06-01 | | 公開日 | 2007-10-09 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'
Nat.Immunol., 8, 2007
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7N3T
 | | TrkA ECD complex with designed miniprotein ligand | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Jude, K.M, Cao, L, Garcia, K.C. | | 登録日 | 2021-06-01 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
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7N2R
 | | AS4.3-PRPF3-HLA*B27 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, ... | | 著者 | Yang, X, Jude, K.M, Garcia, K.C. | | 登録日 | 2021-05-29 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Nature, 612, 2022
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7N2Q
 | | AS4.3-YEIH-HLA*B27 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, AS4.3 T cell receptor beta chain, ... | | 著者 | Yang, X, Jude, K.M, Garcia, K.C. | | 登録日 | 2021-05-29 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Nature, 612, 2022
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7N2N
 | | TCR-antigen complex AS4.2-PRPF3-HLA*B27 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... | | 著者 | Yang, X, Jude, K.M, Garcia, K.C. | | 登録日 | 2021-05-29 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Nature, 612, 2022
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7N2S
 | | AS3.1-PRPF3-HLA*B27 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... | | 著者 | Yang, X, Jude, K.M, Garcia, K.C. | | 登録日 | 2021-05-29 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Nature, 612, 2022
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1JDN
 | | Crystal Structure of Hormone Receptor | | 分子名称: | ATRIAL NATRIURETIC PEPTIDE CLEARANCE RECEPTOR, CHLORIDE ION, beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | He, X.-L, Chow, D.-C, Martick, M.M, Garcia, K.C. | | 登録日 | 2001-06-14 | | 公開日 | 2001-09-05 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Allosteric activation of a spring-loaded natriuretic peptide receptor dimer by hormone.
Science, 293, 2001
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6WW2
 | | Structure of human Frizzled5 by fiducial-assisted cryo-EM | | 分子名称: | Frizzled-5,Soluble cytochrome b562, anti-BRIL Fab Heavy chain, anti-BRIL Fab Light chain, ... | | 著者 | Tsutsumi, N, Jude, K.M, Gati, C, Garcia, K.C. | | 登録日 | 2020-05-07 | | 公開日 | 2020-08-19 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling.
Elife, 9, 2020
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1K2D
 | | Crystal structure of the autoimmune MHC class II I-Au complexed with myelin basic protein 1-11 at 2.2A | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 class II histocompatibility antigen, A-U alpha chain, ... | | 著者 | He, X.L, Radu, C, Ward, E.S, Garcia, K.C. | | 登録日 | 2001-09-26 | | 公開日 | 2003-03-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural snapshot of aberrant antigen presentation linked to autoimmunity: the
immunodominant epitope of MBP complexed with I-Au
IMMUNITY, 17, 2002
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1JDP
 | | Crystal Structure of Hormone/Receptor Complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATRIAL NATRIURETIC PEPTIDE CLEARANCE RECEPTOR, ... | | 著者 | He, X.-L, Chow, D.-C, Martick, M.M, Garcia, K.C. | | 登録日 | 2001-06-14 | | 公開日 | 2001-09-05 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Allosteric activation of a spring-loaded natriuretic peptide receptor dimer by hormone.
Science, 293, 2001
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