5WB2

US28 bound to engineered chemokine CX3CL1.35 and nanobodies

Summary for 5WB2

• Entry DOI: 10.2210/pdb5wb2/pdb
• Descriptor: Envelope protein US28, nanobody 7 fusion protein, CX3CL1 protein, nanobody B1, ... (7 entities in total)
• Functional Keywords: chemokine receptor, engineered proteins, membrane protein
• Biological source: Human cytomegalovirus (HHV-5); More
• Total number of polymer chains: 3
• Total formula weight: 77401.17

Authors

Jude, K.M.,Burg, J.S.,Tsutsumi, N.,Miles, T.F.,Garcia, K.C. (deposition date: 2017-06-27, release date: 2018-06-13, Last modification date: 2023-10-04)

• Primary citation: Miles, T.F.,Spiess, K.,Jude, K.M.,Tsutsumi, N.,Burg, J.S.,Ingram, J.R.,Waghray, D.,Hjorto, G.M.,Larsen, O.,Ploegh, H.L.,Rosenkilde, M.M.,Garcia, K.C.; Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy.; Elife, 7:-, 2018; PubMed: 29882741; DOI: 10.7554/eLife.35850

Experimental method

X-RAY DIFFRACTION (3.5 Å)