5WB1

Ligand-free US28 with stabilizing intracellular nanobody

Summary for 5WB1

DescriptorEnvelope protein US28, nanobody 7 fusion protein (1 entity in total)
Functional Keywordschemokine receptor, membrane protein
Biological sourceHuman cytomegalovirus (HHV-5)
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Total number of polymer chains1
Total molecular weight51827.99
Authors
Jude, K.M.,Burg, J.S.,Garcia, K.C. (deposition date: 2017-06-27, release date: 2018-06-13, Last modification date: 2018-07-25)
Primary citation
Miles, T.F.,Spiess, K.,Jude, K.M.,Tsutsumi, N.,Burg, J.S.,Ingram, J.R.,Waghray, D.,Hjorto, G.M.,Larsen, O.,Ploegh, H.L.,Rosenkilde, M.M.,Garcia, K.C.
Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy.
Elife, 7:-, 2018
PubMed: 29882741 (PDB entries with the same primary citation)
DOI: 10.7554/eLife.35850
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.508 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.28950.2%1.1%1.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5wb1
no rotation
Molmil generated image of 5wb1
rotated about x axis by 90°
Molmil generated image of 5wb1
rotated about y axis by 90°
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