1K2D
Crystal structure of the autoimmune MHC class II I-Au complexed with myelin basic protein 1-11 at 2.2A
Summary for 1K2D
| Entry DOI | 10.2210/pdb1k2d/pdb |
| Descriptor | H-2 class II histocompatibility antigen, A-U alpha chain, H-2 class II histocompatibility antigen, A-U beta chain, Myelin Basic Protein peptide with 8 residue linker peptide, ... (5 entities in total) |
| Functional Keywords | mhc class ii, i-au, h-2u, autoimmune disease, unique register, experimental autoimmune encephalomyelitis, myelin basic protein, immune system |
| Biological source | Mus musculus (house mouse) More |
| Total number of polymer chains | 3 |
| Total formula weight | 46946.99 |
| Authors | He, X.L.,Radu, C.,Ward, E.S.,Garcia, K.C. (deposition date: 2001-09-26, release date: 2003-03-04, Last modification date: 2024-04-03) |
| Primary citation | He, X.L.,Radu, C.,Sidney, J.,Sette, A.,Ward, E.S.,Garcia, K.C. Structural snapshot of aberrant antigen presentation linked to autoimmunity: the immunodominant epitope of MBP complexed with I-Au IMMUNITY, 17:83-94, 2002 Cited by PubMed: 12150894DOI: 10.1016/S1074-7613(02)00340-0 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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