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6QJH
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BU of 6qjh by Molmil
Cryo-EM structure of heparin-induced 2N4R tau snake filaments
分子名称: Microtubule-associated protein tau
著者Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W.
登録日2019-01-24
公開日2019-02-20
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
6QJM
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BU of 6qjm by Molmil
Cryo-EM structure of heparin-induced 2N4R tau twister filaments
分子名称: Microtubule-associated protein tau
著者Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W.
登録日2019-01-24
公開日2019-02-27
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
7NRV
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BU of 7nrv by Molmil
Paired helical filament from Alzheimer's disease with PET ligand APN-1607
分子名称: Microtubule-associated protein tau
著者Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
登録日2021-03-04
公開日2021-03-24
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRQ
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BU of 7nrq by Molmil
Paired helical filament from primary age-related tauopathy brain
分子名称: Microtubule-associated protein tau
著者Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
登録日2021-03-04
公開日2021-03-24
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRT
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BU of 7nrt by Molmil
Conformation 2 of straight filament from primary age-related tauopathy brain
分子名称: Microtubule-associated protein tau
著者Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
登録日2021-03-04
公開日2021-03-24
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRX
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BU of 7nrx by Molmil
Straight filament from Alzheimer's disease with PET ligand APN-1607
分子名称: Microtubule-associated protein tau
著者Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
登録日2021-03-04
公開日2021-03-24
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRS
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BU of 7nrs by Molmil
Conformation 1 of straight filament from primary age-related tauopathy brain
分子名称: Microtubule-associated protein tau
著者Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
登録日2021-03-04
公開日2021-03-24
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
8BGS
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BU of 8bgs by Molmil
Tau Paired Helical Filament from Extracellular Vesicles from Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Behr, T.S, Ryskeldi-Falcon, B.
登録日2022-10-28
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease.
Biorxiv, 2023
8BGV
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BU of 8bgv by Molmil
Tau Paired Helical Filament from Cellular Fraction of Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Behr, T.S, Ryskeldi-Falcon, B.
登録日2022-10-28
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease.
Biorxiv, 2023
8ONS
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BU of 8ons by Molmil
TAF15 amyloid fold in atypical FTLD - Individual 1
分子名称: TATA-binding protein-associated factor 2N
著者Tetter, S, Ryskeldi-Falcon, B.
登録日2023-04-03
公開日2023-12-06
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (1.97 Å)
主引用文献TAF15 amyloid filaments in frontotemporal lobar degeneration.
Nature, 625, 2024
6QJQ
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BU of 6qjq by Molmil
Cryo-EM structure of heparin-induced 2N3R tau filaments
分子名称: Microtubule-associated protein tau
著者Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W.
登録日2019-01-24
公開日2019-02-20
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
6TJO
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BU of 6tjo by Molmil
Cryo-EM structure of TypeI tau filaments extracted from the brains of individuals with Corticobasal degeneration
分子名称: Microtubule-associated protein tau
著者Zhang, W, Murzin, A.G, Falcon, B, Shi, Y, Goedert, M, Scheres, S.H.W.
登録日2019-11-26
公開日2020-02-05
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Novel tau filament fold in corticobasal degeneration.
Nature, 580, 2020
6TJX
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BU of 6tjx by Molmil
Cryo-EM structure of TypeII tau filaments extracted from the brains of individuals with Corticobasal degeneration
分子名称: Microtubule-associated protein tau
著者Zhang, W, Murzin, A.G, Falcon, B, Shi, Y, Goedert, M, Scheres, S.H.W.
登録日2019-11-27
公開日2020-02-05
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Novel tau filament fold in corticobasal degeneration.
Nature, 580, 2020
8OTI
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BU of 8oti by Molmil
CTE typeIII tau filament
分子名称: Microtubule-associated protein tau
著者Tetter, S, Qi, C, Ryskeldi-Falcon, B, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
6VI3
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BU of 6vi3 by Molmil
Straight Filament from Alzheimer's Disease Human Brain Tissue
分子名称: GLYCINE, Microtubule-associated protein tau
著者Arakhamia, T, Lee, C.E, Carlomagno, Y, Duong, D.M, Kundinger, S.R, Wang, K, Williams, D, DeTure, M, Dickson, D.W, Cook, C.N, Seyfried, N.T, Petrucelli, L, Fitzpatrick, A.W.P.
登録日2020-01-11
公開日2020-04-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains
Cell, 180, 2020
7QWM
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BU of 7qwm by Molmil
TMEM106B filaments with Fold III from Multiple system atrophy (case 17)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-25
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QVF
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BU of 7qvf by Molmil
TMEM106B filaments with Fold I-d from Multiple system atrophy (case 18)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-21
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QVC
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BU of 7qvc by Molmil
TMEM106B filaments with Fold I from Alzheimer's disease (case 1)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-21
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWL
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BU of 7qwl by Molmil
TMEM106B filaments with Fold IIb from Multiple system atrophy (case 19)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-25
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWG
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BU of 7qwg by Molmil
TMEM106B filaments with Fold IIa from Multiple system atrophy (case 19)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-25
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
8OTD
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BU of 8otd by Molmil
TMEM106B Fold1-s filament from Guam ALS/PDC
分子名称: Transmembrane protein 106B
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTH
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BU of 8oth by Molmil
TypeII tau filament from Kii ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OT6
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BU of 8ot6 by Molmil
CTE typeI tau filament from Guam ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (2 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTJ
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BU of 8otj by Molmil
PHF tau filament from Kii ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTF
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BU of 8otf by Molmil
Ab typeII filament from Guam ALS/PDC
分子名称: Amyloid-beta precursor protein
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023

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