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4W8Z
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BU of 4w8z by Molmil
Crystal structure of Cmr1 from Pyrococcus furiosus (apo form)
分子名称: CRISPR system Cmr subunit Cmr1-1
著者Benda, C, Ebert, J, Baumgaertner, M, Conti, E.
登録日2014-08-26
公開日2014-10-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Model of a CRISPR RNA-Silencing Complex Reveals the RNA-Target Cleavage Activity in Cmr4.
Mol.Cell, 56, 2014
4W8W
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BU of 4w8w by Molmil
Crystal structure of oligomeric Cmr4 from Pyrococcus furiosus
分子名称: CRISPR system Cmr subunit Cmr4
著者Benda, C, Ebert, J, Baumgaertner, M, Conti, E.
登録日2014-08-26
公開日2014-10-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献Structural Model of a CRISPR RNA-Silencing Complex Reveals the RNA-Target Cleavage Activity in Cmr4.
Mol.Cell, 56, 2014
1YA0
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BU of 1ya0 by Molmil
Crystal structure of the N-terminal domain of human SMG7
分子名称: SMG-7 transcript variant 2, SULFATE ION
著者Fukuhara, N, Ebert, J, Unterholzner, L, Lindner, D, Izaurralde, E, Conti, E.
登録日2004-12-17
公開日2005-03-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献SMG7 Is a 14-3-3-like Adaptor in the Nonsense-Mediated mRNA Decay Pathway.
Mol.Cell, 17, 2005
4N0L
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BU of 4n0l by Molmil
Methanopyrus kandleri Csm3 crystal structure
分子名称: Predicted component of a thermophile-specific DNA repair system, contains a RAMP domain, ZINC ION
著者Hrle, A, Su, A.A, Ebert, J, Benda, C, Conti, E, Randau, L.
登録日2013-10-02
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structure and RNA-binding properties of the Type III-A CRISPR-associated protein Csm3.
Rna Biol., 10, 2013
1Z3H
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BU of 1z3h by Molmil
The exportin Cse1 in its cargo-free, cytoplasmic state
分子名称: Importin alpha re-exporter, MAGNESIUM ION
著者Cook, A, Fernandez, E, Lindner, D, Ebert, J, Schlenstedt, G, Conti, E.
登録日2005-03-12
公開日2005-05-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The structure of the nuclear export receptor cse1 in its cytosolic state reveals a closed conformation incompatible with cargo binding
Mol.Cell, 18, 2005
6Z3R
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BU of 6z3r by Molmil
Structure of SMG1-8-9 kinase complex bound to UPF1-LSQ
分子名称: ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
著者Langer, L.M, Gat, Y, Conti, E.
登録日2020-05-21
公開日2020-06-24
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity.
Elife, 9, 2020
2QFA
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BU of 2qfa by Molmil
Crystal structure of a Survivin-Borealin-INCENP core complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Baculoviral IAP repeat-containing protein 5, Borealin, ...
著者Jeyaprakash, A.A, Klein, U.R, Lindner, D, Ebert, J, Nigg, E.A, Conti, E.
登録日2007-06-27
公開日2007-11-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of a Survivin-Borealin-INCENP Core Complex Reveals How Chromosomal Passengers Travel Together.
Cell(Cambridge,Mass.), 131, 2007
8QCF
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BU of 8qcf by Molmil
yeast cytoplasmic exosome-Ski2 complex degrading a RNA substrate
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Antiviral helicase SKI2, Exosome complex component CSL4, ...
著者Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E.
登録日2023-08-25
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (2.55 Å)
主引用文献Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly.
Mol.Cell, 83, 2023
8QCB
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BU of 8qcb by Molmil
CryoEM structure of a S. Cerevisiae Ski2387 complex in the open state
分子名称: Antiviral helicase SKI2, Antiviral protein SKI8, Superkiller protein 3, ...
著者Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E.
登録日2023-08-25
公開日2023-11-08
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly.
Mol.Cell, 83, 2023
8QCA
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BU of 8qca by Molmil
CryoEM structure of a S. Cerevisiae Ski2387 complex in the closed state bound to RNA
分子名称: Antiviral helicase SKI2, Antiviral protein SKI8, RNA (5'-R(P*UP*UP*UP*U)-3'), ...
著者Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E.
登録日2023-08-25
公開日2023-11-15
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly.
Mol.Cell, 83, 2023
8Q9T
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BU of 8q9t by Molmil
CryoEM structure of a S. Cerevisiae Ski238 complex bound to RNA
分子名称: Antiviral helicase SKI2, Antiviral protein SKI8, RNA (5'-R(P*UP*UP*UP*U)-3'), ...
著者Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E.
登録日2023-08-21
公開日2023-11-29
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly.
Mol.Cell, 83, 2023
7AQO
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BU of 7aqo by Molmil
yeast THO-Sub2 complex dimer
分子名称: BJ4_G0025130.mRNA.1.CDS.1, EM14S01-3B_G0007820.mRNA.1.CDS.1, TEX1 isoform 1, ...
著者Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E.
登録日2020-10-22
公開日2020-12-02
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex.
Elife, 9, 2020
5JNB
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BU of 5jnb by Molmil
structure of GLD-2/RNP-8 complex
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, Poly(A) RNA polymerase gld-2, ...
著者Nakel, K, Bonneau, F, Basquin, C, Eckmann, C.R, Conti, E.
登録日2016-04-29
公開日2016-06-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.486 Å)
主引用文献Structural basis for the antagonistic roles of RNP-8 and GLD-3 in GLD-2 poly(A)-polymerase activity.
Rna, 22, 2016
7APX
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BU of 7apx by Molmil
yeast THO-Sub2 complex
分子名称: ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2,Tho2, ...
著者Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E.
登録日2020-10-20
公開日2020-12-02
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex.
Elife, 9, 2020
6FT6
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BU of 6ft6 by Molmil
Structure of the Nop53 pre-60S particle bound to the exosome nuclear cofactors
分子名称: 25S ribosomal RNA, 5S ribosomal RNA, 60S ribosomal protein L11-A, ...
著者Schuller, J.M, Falk, S, Conti, E.
登録日2018-02-20
公開日2018-03-28
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structure of the nuclear exosome captured on a maturing preribosome.
Science, 360, 2018
6FSZ
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BU of 6fsz by Molmil
Structure of the nuclear RNA exosome
分子名称: ATP-dependent RNA helicase DOB1, Exosome complex component CSL4, Exosome complex component MTR3, ...
著者Schuller, J.M, Falk, S, Conti, E.
登録日2018-02-20
公開日2018-03-21
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structure of the nuclear exosome captured on a maturing preribosome.
Science, 360, 2018
3FHT
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BU of 3fht by Molmil
Crystal structure of human Dbp5 in complex with AMPPNP and RNA
分子名称: ATP-dependent RNA helicase DDX19B, GLYCEROL, MAGNESIUM ION, ...
著者von Moeller, H, Conti, E.
登録日2008-12-10
公開日2009-02-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner
Nat.Struct.Mol.Biol., 16, 2009
3FHC
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BU of 3fhc by Molmil
Crystal structure of human Dbp5 in complex with Nup214
分子名称: ATP-dependent RNA helicase DDX19B, Nuclear pore complex protein Nup214
著者von Moeller, H, Conti, E.
登録日2008-12-09
公開日2009-02-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner
Nat.Struct.Mol.Biol., 16, 2009
3ICQ
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BU of 3icq by Molmil
Karyopherin nuclear state
分子名称: Exportin-T, GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Cook, A.G, Fukuhara, N, Jinek, M, Conti, E.
登録日2009-07-18
公開日2009-08-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structures of the tRNA export factor in the nuclear and cytosolic states
Nature, 461, 2009
3IBV
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BU of 3ibv by Molmil
Karyopherin cytosolic state
分子名称: CALCIUM ION, Exportin-T
著者Cook, A.G, Fukuhara, N, Jinek, M, Conti, E.
登録日2009-07-17
公開日2009-08-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of the tRNA export factor in the nuclear and cytosolic states
Nature, 461, 2009
6R5K
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BU of 6r5k by Molmil
Cryo-EM structure of a poly(A) RNP bound to the Pan2-Pan3 deadenylase
分子名称: MAGNESIUM ION, PAN2-PAN3 deadenylation complex catalytic subunit PAN2, PAN2-PAN3 deadenylation complex subunit PAN3, ...
著者Schaefer, I.B, Conti, E.
登録日2019-03-25
公開日2019-05-29
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Molecular Basis for poly(A) RNP Architecture and Recognition by the Pan2-Pan3 Deadenylase.
Cell, 177, 2019
8R8R
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BU of 8r8r by Molmil
Cryo-EM structure of the human mPSF with PAPOA C-terminus peptide (PAPOAc)
分子名称: Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*AP*AP*UP*AP*AP*A)-3'), ...
著者Todesca, S, Sandmeir, F, Keidel, A, Conti, E.
登録日2023-11-29
公開日2024-04-10
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Molecular basis of human poly(A) polymerase recruitment by mPSF.
Rna, 30, 2024
8RXB
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BU of 8rxb by Molmil
Human UPF1 CH domain in complex with SMG6 peptide
分子名称: Regulator of nonsense transcripts 1, Telomerase-binding protein EST1A, ZINC ION
著者Langer, L, Basquin, J, Conti, E.
登録日2024-02-06
公開日2024-05-15
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献UPF1 helicase orchestrates mutually exclusive interactions with the SMG6 endonuclease and UPF2.
Nucleic Acids Res., 52, 2024
4ZKE
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BU of 4zke by Molmil
Crystal structure of the S. cerevisiae Ski7 GTPase-like domain, bound to GTP.
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SODIUM ION, ...
著者Kowalinski, E, Conti, E.
登録日2015-04-30
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献Saccharomyces cerevisiae Ski7 Is a GTP-Binding Protein Adopting the Characteristic Conformation of Active Translational GTPases.
Structure, 23, 2015
4ZKD
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BU of 4zkd by Molmil
Crystal structure of the S. cerevisiae Ski7 GTPase-like domain, bound to GDP and inorganic phosphate.
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Kowalinski, E, Conti, E.
登録日2015-04-30
公開日2015-06-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.181 Å)
主引用文献Saccharomyces cerevisiae Ski7 Is a GTP-Binding Protein Adopting the Characteristic Conformation of Active Translational GTPases.
Structure, 23, 2015

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