3FHC

Crystal structure of human Dbp5 in complex with Nup214

Summary for 3FHC

Entry DOI	10.2210/pdb3fhc/pdb
Related	2OIT 3FHT
Descriptor	Nuclear pore complex protein Nup214, ATP-dependent RNA helicase DDX19B (3 entities in total)
Functional Keywords	dead-box helicase, mrna export, nucleoporin, beta propeller, reca-like, rna dependent atpase, can, ddx19, dead-box protein 19b, nuclear pore complex, glycoprotein, mrna transport, nucleus, phosphoprotein, protein transport, proto-oncogene, translocation, transport, atp-binding, helicase, hydrolase, membrane, nucleotide-binding, rna-binding, transport protein-hydrolase complex, transport protein/hydrolase
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	71522.53
Authors	von Moeller, H.,Conti, E. (deposition date: 2008-12-09, release date: 2009-02-17, Last modification date: 2023-11-01)
Primary citation	von Moeller, H.,Basquin, C.,Conti, E. The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner Nat.Struct.Mol.Biol., 16:247-254, 2009 Cited by PubMed: 19219046 DOI: 10.1038/nsmb.1561 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation