6SYT

Structure of the SMG1-SMG8-SMG9 complex

Summary for 6SYT

Entry DOI	10.2210/pdb6syt/pdb
EMDB information	10347
Descriptor	SMG1,Serine/threonine-protein kinase SMG1,SMG1,Serine/threonine-protein kinase SMG1,SMG1,Serine/threonine-protein kinase SMG1,SMG1,Serine/threonine-protein kinase SMG1,SMG1,Serine/threonine-protein kinase SMG1, Protein SMG8, Protein SMG9, ... (6 entities in total)
Functional Keywords	kinase, nmd, ip6, g-fold protein, pikk family, signaling protein
Biological source	Homo sapiens More
Total number of polymer chains	3
Total formula weight	570138.68
Authors	Gat, Y.,Schuller, J.M.,Conti, E. (deposition date: 2019-10-01, release date: 2019-12-11, Last modification date: 2020-10-07)
Primary citation	Gat, Y.,Schuller, J.M.,Lingaraju, M.,Weyher, E.,Bonneau, F.,Strauss, M.,Murray, P.J.,Conti, E. InsP6binding to PIKK kinases revealed by the cryo-EM structure of an SMG1-SMG8-SMG9 complex. Nat.Struct.Mol.Biol., 26:1089-1093, 2019 Cited by PubMed: 31792449 DOI: 10.1038/s41594-019-0342-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.45 Å)

Structure validation