3FHT
Crystal structure of human Dbp5 in complex with AMPPNP and RNA
Summary for 3FHT
Entry DOI | 10.2210/pdb3fht/pdb |
Related | 3FHC |
Descriptor | ATP-dependent RNA helicase DDX19B, RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | dbp5, dead-box helicase, rna dependent atpase, mrna export, nucleocytoplasmic transport, nup214, can, nup159, ddx19b, nuclear pore, gle1, atp-binding, helicase, hydrolase, membrane, mrna transport, nuclear pore complex, nucleotide-binding, nucleus, phosphoprotein, protein transport, rna-binding, translocation, transport, hydrolase-rna complex, hydrolase/rna |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: Q9UMR2 |
Total number of polymer chains | 4 |
Total formula weight | 100708.07 |
Authors | von Moeller, H.,Conti, E. (deposition date: 2008-12-10, release date: 2009-02-17, Last modification date: 2023-11-01) |
Primary citation | von Moeller, H.,Basquin, C.,Conti, E. The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner Nat.Struct.Mol.Biol., 16:247-254, 2009 Cited by PubMed: 19219046DOI: 10.1038/nsmb.1561 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report