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3EQC
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X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a ternary complex with compound 1, ATP-GS AND MG2P
分子名称: 2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide, CALCIUM ION, Dual specificity mitogen-activated protein kinase kinase 1, ...
著者Fischmann, T.O.
登録日2008-09-30
公開日2009-02-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors.
Biochemistry, 48, 2009
3EQF
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X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a binary complex with K252A and MG2P
分子名称: CALCIUM ION, Dual specificity mitogen-activated protein kinase kinase 1, K-252A, ...
著者Fischmann, T.O.
登録日2008-09-30
公開日2009-02-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors.
Biochemistry, 48, 2009
3EQH
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BU of 3eqh by Molmil
X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a ternary complex with U0126, ADP and MG2P
分子名称: (2Z)-bis{amino[(2-aminophenyl)sulfanyl]methylidene}butanedinitrile, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
著者Fischmann, T.O.
登録日2008-09-30
公開日2009-02-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors.
Biochemistry, 48, 2009
4FBE
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BU of 4fbe by Molmil
Crystal structure of the C136A/C164A variant of mitochondrial isoform of glutaminyl cyclase from Drosophila melanogaster
分子名称: 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, CG5976, isoform B, ...
著者Kolenko, P, Koch, B, Ruiz-Carilo, D, Stubbs, M.T.
登録日2012-05-23
公開日2012-08-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Crystal Structures of Glutaminyl Cyclases (QCs) from Drosophila melanogaster Reveal Active Site Conservation between Insect and Mammalian QCs.
Biochemistry, 51, 2012
4F9U
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BU of 4f9u by Molmil
Structure of glycosylated glutaminyl cyclase from Drosophila melanogaster
分子名称: 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CG32412, ...
著者Kolenko, P, Koch, B, Ruiz-Carilo, D, Stubbs, M.T.
登録日2012-05-21
公開日2012-08-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of Glutaminyl Cyclases (QCs) from Drosophila melanogaster Reveal Active Site Conservation between Insect and Mammalian QCs.
Biochemistry, 51, 2012
4F9V
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BU of 4f9v by Molmil
Structure of C113A/C136A mutant variant of glycosylated glutaminyl cyclase from Drosophila melanogaster
分子名称: 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, CG32412, DI(HYDROXYETHYL)ETHER, ...
著者Kolenko, P, Koch, B, Ruiz-Carilo, D, Stubbs, M.T.
登録日2012-05-21
公開日2012-08-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of Glutaminyl Cyclases (QCs) from Drosophila melanogaster Reveal Active Site Conservation between Insect and Mammalian QCs.
Biochemistry, 51, 2012
7YZ4
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BU of 7yz4 by Molmil
Mouse endoribonuclease Dicer (composite structure)
分子名称: Endoribonuclease Dicer
著者Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J.
登録日2022-02-18
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
7YYM
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BU of 7yym by Molmil
Mammalian Dicer in the "pre-dicing state" with pre-miR-15a substrate
分子名称: 59-nt precursor of miR-15a, Endoribonuclease Dicer
著者Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J.
登録日2022-02-18
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (4.19 Å)
主引用文献Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
7YYN
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BU of 7yyn by Molmil
Mammalian Dicer in the dicing state with pre-miR-15a substrate
分子名称: 59-nt precursor of miR-15a, Isoform 2 of Endoribonuclease Dicer
著者Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J.
登録日2022-02-18
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (6.21 Å)
主引用文献Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
7ZPJ
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BU of 7zpj by Molmil
Mammalian Dicer in the "pre-dicing state" with pre-miR-15a substrate and TARBP2 subunit
分子名称: 59-nt precursor of miR-15a, Endoribonuclease Dicer, RISC-loading complex subunit TARBP2 isoform 1
著者Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J.
登録日2022-04-27
公開日2022-12-28
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
7ZPK
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BU of 7zpk by Molmil
Mammalian Dicer in the "pre-dicing state" with pre-miR-15a substrate and TARBP2 subunit
分子名称: 59-nt precursor of miR-15a, Endoribonuclease Dicer, RISC-loading complex subunit TARBP2
著者Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J.
登録日2022-04-27
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
7ZPI
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BU of 7zpi by Molmil
Mammalian Dicer in the "dicing state" with pre-miR-15a substrate
分子名称: 59-nt precursor of miR-15a, Endoribonuclease Dicer
著者Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J.
登録日2022-04-27
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (5.91 Å)
主引用文献Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
8OVU
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BU of 8ovu by Molmil
Human titin immunoglobulin-like 21 domain
分子名称: MAGNESIUM ION, Titin
著者Martinez-Martin, I, Crousilles, A, Mortensen, S.A, Alegre-Cebollada, J, Wilmanns, M.
登録日2023-04-26
公開日2023-11-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Titin domains with reduced core hydrophobicity cause dilated cardiomyopathy.
Cell Rep, 42, 2023
8P35
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BU of 8p35 by Molmil
Mutant human titin immunoglobulin-like 21 domain - C3575S
分子名称: Titin
著者Martinez-Martin, I, Crousilles, A, Mortensen, S.A, Alegre-Cebollada, J, Wilmanns, M.
登録日2023-05-17
公開日2023-11-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Titin domains with reduced core hydrophobicity cause dilated cardiomyopathy.
Cell Rep, 42, 2023
1C4K
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BU of 1c4k by Molmil
ORNITHINE DECARBOXYLASE MUTANT (GLY121TYR)
分子名称: GUANOSINE-5'-TRIPHOSPHATE, PROTEIN (ORNITHINE DECARBOXYLASE), PYRIDOXAL-5'-PHOSPHATE
著者Vitali, J, Hackert, M.L.
登録日1999-08-26
公開日2000-02-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Three-dimensional structure of the Gly121Tyr dimeric form of ornithine decarboxylase from Lactobacillus 30a.
Acta Crystallogr.,Sect.D, 55, 1999
7P9B
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BU of 7p9b by Molmil
Providencia stuartii Arginine decarboxylase (Adc), decamer structure
分子名称: Biodegradative arginine decarboxylase
著者Jessop, M, Desfosses, A, Bacia-Verloop, M, Gutsche, I.
登録日2021-07-26
公開日2022-04-20
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献Structural and biochemical characterisation of the Providencia stuartii arginine decarboxylase shows distinct polymerisation and regulation.
Commun Biol, 5, 2022
7PK6
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BU of 7pk6 by Molmil
Providencia stuartii Arginine decarboxylase (Adc), stack structure
分子名称: Biodegradative arginine decarboxylase
著者Jessop, M, Desfosses, A, Bacia-Verloop, M, Gutsche, I.
登録日2021-08-25
公開日2022-04-20
実験手法ELECTRON MICROSCOPY (2.15 Å)
主引用文献Structural and biochemical characterisation of the Providencia stuartii arginine decarboxylase shows distinct polymerisation and regulation.
Commun Biol, 5, 2022
4FAI
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BU of 4fai by Molmil
Crystal structure of mitochondrial isoform of glutaminyl cyclase from Drosophila melanogaster
分子名称: 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, CG5976, isoform B, ...
著者Kolenko, P, Koch, B, Ruiz-Carilo, D, Stubbs, M.T.
登録日2012-05-22
公開日2012-08-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal Structures of Glutaminyl Cyclases (QCs) from Drosophila melanogaster Reveal Active Site Conservation between Insect and Mammalian QCs.
Biochemistry, 51, 2012
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