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7YZ4

Mouse endoribonuclease Dicer (composite structure)

Summary for 7YZ4
Entry DOI10.2210/pdb7yz4/pdb
Related7YYM 7YYN
EMDB information14383 14384 14387 15297 15298 15299
DescriptorEndoribonuclease Dicer (1 entity in total)
Functional Keywordsendoribonuclease, gene silencing, post-transcriptional, catalytic enzyme, cytoplasm, rna binding protein
Biological sourceMus musculus (house mouse)
Total number of polymer chains1
Total formula weight226809.59
Authors
Zanova, M.,Zapletal, D.,Kubicek, K.,Stefl, R.,Pinkas, M.,Novacek, J. (deposition date: 2022-02-18, release date: 2022-11-16)
Primary citationZapletal, D.,Taborska, E.,Pasulka, J.,Malik, R.,Kubicek, K.,Zanova, M.,Much, C.,Sebesta, M.,Buccheri, V.,Horvat, F.,Jenickova, I.,Prochazkova, M.,Prochazka, J.,Pinkas, M.,Novacek, J.,Joseph, D.F.,Sedlacek, R.,Bernecky, C.,O'Carroll, D.,Stefl, R.,Svoboda, P.
Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82:4064-4079.e13, 2022
Cited by
PubMed: 36332606
DOI: 10.1016/j.molcel.2022.10.010
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.84 Å)
Structure validation

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