Search by PDB author - 日本蛋白質構造データバンク

English 日本語简体中文繁體中文 한국어

✖

ﾒﾆｭｰ

RCSB PDB PDBe BMRB Adv. Search Search help

Search by PDB author

Visualize

BU of 2avs by Molmil

kinetics, stability, and structural changes in high resolution crystal structures of HIV-1 protease with drug resistant mutations L24I, I50V, and G73S
分子名称:	ACETIC ACID, DIMETHYL SULFOXIDE, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE, ...
著者	Liu, F, Boross, P.I, Wang, Y.F, Tozser, J, Louis, J.M, Harrison, R.W, Weber, I.T.
登録日	2005-08-30
公開日	2006-01-24
最終更新日	2023-08-23
実験手法	X-RAY DIFFRACTION (1.1 Å)
主引用文献	Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S. J.Mol.Biol., 354, 2005

Visualize

BU of 2aoh by Molmil

Crystal structure analysis of HIV-1 Protease mutant V82A with a substrate analog P6-PR
分子名称:	CHLORIDE ION, PEPTIDE INHIBITOR, POL POLYPROTEIN, ...
著者	Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T.
登録日	2005-08-12
公開日	2006-01-17
最終更新日	2023-08-23
実験手法	X-RAY DIFFRACTION (1.42 Å)
主引用文献	Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs. Febs J., 272, 2005

Visualize

BU of 3s45 by Molmil

wild-type HIV-2 protease with antiviral drug amprenavir
分子名称:	CHLORIDE ION, IMIDAZOLE, Protease, ...
著者	Tie, Y.-F, Wang, Y.-F, Weber, I.T.
登録日	2011-05-18
公開日	2012-03-21
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (1.51 Å)
主引用文献	Critical differences in HIV-1 and HIV-2 protease specificity for clinical inhibitors. Protein Sci., 21, 2012

Visualize

BU of 3s56 by Molmil

HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug saquinavir
分子名称:	(2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, ACETATE ION, Protease
著者	Tie, Y.-F, Wang, Y.-F, Weber, I.T.
登録日	2011-05-20
公開日	2012-03-21
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (1.88 Å)
主引用文献	Critical differences in HIV-1 and HIV-2 protease specificity for clinical inhibitors. Protein Sci., 21, 2012

Visualize

BU of 3s53 by Molmil

HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P212121
分子名称:	(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, IODIDE ION, PHOSPHATE ION, ...
著者	Tie, Y.-F, Wang, Y.-F, Weber, I.T.
登録日	2011-05-20
公開日	2012-03-21
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (1.5 Å)
主引用文献	Critical differences in HIV-1 and HIV-2 protease specificity for clinical inhibitors. Protein Sci., 21, 2012

Visualize

BU of 3s43 by Molmil

HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug amprenavir
分子名称:	GLYCEROL, IODIDE ION, Protease, ...
著者	Wang, Y.-F, Tie, Y.-F, Weber, I.T.
登録日	2011-05-18
公開日	2012-03-21
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (1.26 Å)
主引用文献	Critical differences in HIV-1 and HIV-2 protease specificity for clinical inhibitors. Protein Sci., 21, 2012

Visualize

BU of 3s54 by Molmil

HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P21212
分子名称:	(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETATE ION, CHLORIDE ION, ...
著者	Tie, Y.-F, Wang, Y.-F, Weber, I.T.
登録日	2011-05-20
公開日	2012-03-21
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (1.42 Å)
主引用文献	Critical differences in HIV-1 and HIV-2 protease specificity for clinical inhibitors. Protein Sci., 21, 2012

Visualize

BU of 2g69 by Molmil

Structure of Unliganded HIV-1 Protease F53L Mutant
分子名称:	protease
著者	Kovalevsky, A.Y, Liu, F.
登録日	2006-02-24
公開日	2006-05-09
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.35 Å)
主引用文献	Mechanism of Drug Resistance Revealed by the Crystal Structure of the Unliganded HIV-1 Protease with F53L Mutation. J.Mol.Biol., 358, 2006

Visualize

BU of 2f80 by Molmil

HIV-1 Protease mutant D30N complexed with inhibitor TMC114
分子名称:	(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, POL POLYPROTEIN, ...
著者	Kovalevsky, A.Y, Weber, I.T.
登録日	2005-12-01
公開日	2006-03-07
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.45 Å)
主引用文献	Effectiveness of Nonpeptide Clinical Inhibitor TMC-114 on HIV-1 Protease with Highly Drug Resistant Mutations D30N, I50V, and L90M. J.Med.Chem., 49, 2006

Visualize

BU of 2f81 by Molmil

HIV-1 Protease mutant L90M complexed with inhibitor TMC114
分子名称:	(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, GLYCEROL, ...
著者	Kovalevsky, A.Y, Weber, I.T.
登録日	2005-12-01
公開日	2006-03-07
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.25 Å)
主引用文献	Effectiveness of Nonpeptide Clinical Inhibitor TMC-114 on HIV-1 Protease with Highly Drug Resistant Mutations D30N, I50V, and L90M. J.Med.Chem., 49, 2006

Visualize

BU of 2f8g by Molmil

HIV-1 protease mutant I50V complexed with inhibitor TMC114
分子名称:	(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETIC ACID, CHLORIDE ION, ...
著者	Kovalevsky, A.Y, Weber, I.T.
登録日	2005-12-02
公開日	2006-03-07
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.22 Å)
主引用文献	Effectiveness of Nonpeptide Clinical Inhibitor TMC-114 on HIV-1 Protease with Highly Drug Resistant Mutations D30N, I50V, and L90M. J.Med.Chem., 49, 2006

Visualize

BU of 3bvb by Molmil

Cystal structure of HIV-1 Active Site Mutant D25N and inhibitor Darunavir
分子名称:	(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, GLYCEROL, ...
著者	Liu, F, Weber, I.T.
登録日	2008-01-05
公開日	2008-04-01
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.3 Å)
主引用文献	Effect of the Active Site D25N Mutation on the Structure, Stability, and Ligand Binding of the Mature HIV-1 Protease. J.Biol.Chem., 283, 2008

Visualize

BU of 3d1y by Molmil

Crystal structure of HIV-1 mutant I54V and inhibitor SAQUINA
分子名称:	(2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, CHLORIDE ION, HIV-1 Protease, ...
著者	Liu, F, Weber, I.T.
登録日	2008-05-06
公開日	2008-05-27
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (1.05 Å)
主引用文献	Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir. J.Mol.Biol., 381, 2008

Visualize

BU of 3bva by Molmil

Cystal structure of HIV-1 Active Site Mutant D25N and p2-NC analog inhibitor
分子名称:	GLYCEROL, N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide, Protease (Retropepsin)
著者	Liu, F, Weber, I.T.
登録日	2008-01-05
公開日	2008-04-01
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.05 Å)
主引用文献	Effect of the Active Site D25N Mutation on the Structure, Stability, and Ligand Binding of the Mature HIV-1 Protease. J.Biol.Chem., 283, 2008

Visualize

BU of 3d20 by Molmil

Crystal structure of HIV-1 mutant I54V and inhibitor DARUNAVIA
分子名称:	(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, HIV-1 Protease, ...
著者	Liu, F, Kovalesky, A.Y, Tie, Y, Ghosh, A.K, Harrison, R.W, Weber, I.T.
登録日	2008-05-07
公開日	2008-05-27
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.05 Å)
主引用文献	Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir. J.Mol.Biol., 381, 2008

Visualize

BU of 3cyw by Molmil

Effect of Flap Mutations on Structure of HIV-1 Protease and Inhibition by Saquinavir and Darunavir
分子名称:	(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, GLYCEROL, ...
著者	Liu, F, Weber, I.T.
登録日	2008-04-27
公開日	2008-05-27
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.4 Å)
主引用文献	Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir. J.Mol.Biol., 381, 2008

Visualize

BU of 3cyx by Molmil

Crystal structure of HIV-1 mutant I50V and inhibitor saquinavira
分子名称:	(2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, ACETIC ACID, GLYCEROL, ...
著者	Liu, F, Weber, I.T.
登録日	2008-04-27
公開日	2008-05-27
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.2 Å)
主引用文献	Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir. J.Mol.Biol., 381, 2008

Visualize

BU of 3d1z by Molmil

Crystal structure of HIV-1 mutant I54M and inhibitor DARUNAVIR
分子名称:	(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETIC ACID, CHLORIDE ION, ...
著者	Liu, F, Kovalesky, A.Y, Tie, Y, Ghosh, A.K, Harrison, R.W, Weber, I.T.
登録日	2008-05-07
公開日	2008-05-27
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.3 Å)
主引用文献	Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir. J.Mol.Biol., 381, 2008

Visualize

BU of 3d1x by Molmil

Crystal structure of HIV-1 mutant I54M and inhibitor saquinavir
分子名称:	(2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, CHLORIDE ION, GLYCEROL, ...
著者	Liu, F, Weber, I.T.
登録日	2008-05-06
公開日	2008-06-03
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.05 Å)
主引用文献	Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir. J.Mol.Biol., 381, 2008

222926

件を2024-07-24に公開中

PDB statistics

PDBj update info

Contact PDBj

numon