2G69

Structure of Unliganded HIV-1 Protease F53L Mutant

Summary for 2G69

Entry DOI	10.2210/pdb2g69/pdb
Descriptor	protease (2 entities in total)
Functional Keywords	aspartic protease, catalysis, unliganded, flap mutant, non-active site mutant, hydrolase
Biological source	Human immunodeficiency virus 1
Total number of polymer chains	1
Total formula weight	10706.66
Authors	Kovalevsky, A.Y.,Liu, F. (deposition date: 2006-02-24, release date: 2006-05-09, Last modification date: 2024-02-14)
Primary citation	Liu, F.,Kovalevsky, A.Y.,Louis, J.M.,Boross, P.I.,Wang, Y.F.,Harrison, R.W.,Weber, I.T. Mechanism of Drug Resistance Revealed by the Crystal Structure of the Unliganded HIV-1 Protease with F53L Mutation. J.Mol.Biol., 358:1191-1199, 2006 Cited by PubMed: 16569415 DOI: 10.1016/j.jmb.2006.02.076 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.35 Å)

Structure validation