4DVB
| The crystal structure of the Fab fragment of pro-uPA antibody mAb-112 | 分子名称: | Fab fragment of pro-uPA antibody mAb-112, SULFATE ION, TETRAETHYLENE GLYCOL | 著者 | Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M. | 登録日 | 2012-02-23 | 公開日 | 2013-01-16 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Rezymogenation of active urokinase induced by an inhibitory antibody. Biochem.J., 449, 2013
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5WXT
| Crystal structure of uPA-S195A in complex with S2444 | 分子名称: | (2R)-N-[2-[[(2S)-1-[[4-[bis(oxidanyl)amino]phenyl]amino]-5-carbamimidamido-1-oxidanylidene-pentan-2-yl]amino]-2-oxidanylidene-ethyl]-5-oxidanylidene-pyrrolidine-2-carboxamide, Urokinase-type plasminogen activator chain B | 著者 | Jiang, L, Huang, M. | 登録日 | 2017-01-08 | 公開日 | 2018-07-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of uPA-S195A in complex with S2444 To Be Published
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5WXP
| Crystal structure of uPA in complex with upain-2-3-W3A | 分子名称: | ALANINE, CYSTEINE, Urokinase-type plasminogen activator chain B, ... | 著者 | Jiang, L, Huang, M. | 登録日 | 2017-01-08 | 公開日 | 2018-07-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition. Biochim. Biophys. Acta, 1862, 2018
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5WXQ
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5WXF
| Crystal structure of uPA in complex with upain-2-2 | 分子名称: | SULFATE ION, Urokinase-type plasminogen activator chain B, upain-2-2 peptide | 著者 | Jiang, L, Huang, M. | 登録日 | 2017-01-07 | 公開日 | 2018-07-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition. Biochim. Biophys. Acta, 1862, 2018
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5WXR
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5WXO
| Crystal structure of uPA in complex with upain-2-2-W3A | 分子名称: | Urokinase-type plasminogen activator chain B, upain-2-2-W3A peptide | 著者 | Jiang, L, Huang, M. | 登録日 | 2017-01-08 | 公開日 | 2018-07-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition. Biochim. Biophys. Acta, 1862, 2018
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5WXS
| Crystal structure of uPA in complex with S2444 | 分子名称: | (2R)-N-[2-[[(2S)-5-carbamimidamido-1-oxidanylidene-pentan-2-yl]amino]-2-oxidanylidene-ethyl]-5-oxidanylidene-1,2-dihydropyrrole-2-carboxamide, Urokinase-type plasminogen activator chain B | 著者 | Jiang, L, Huang, M. | 登録日 | 2017-01-08 | 公開日 | 2018-07-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of uPA in complex with S2444 To Be Published
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5XUW
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5Y5C
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8IOF
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8IN0
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8ID1
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7D42
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7VUE
| Structural insight of the molecular mechanism of cilofexor bound to FXR | 分子名称: | 2-[3-[4-[[3-[2,6-bis(chloranyl)phenyl]-5-cyclopropyl-1,2-oxazol-4-yl]methoxy]-2-chloranyl-phenyl]-3-oxidanyl-azetidin-1-yl]pyridine-4-carboxylic acid, Bile acid receptor, Peptide from Nuclear receptor coactivator 2 | 著者 | Jiang, L, Chen, Y.C. | 登録日 | 2021-11-02 | 公開日 | 2022-03-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | 主引用文献 | Structural insight into the molecular mechanism of cilofexor binding to the farnesoid X receptor. Biochem.Biophys.Res.Commun., 595, 2022
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7CJ1
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4X1N
| The crystal structure of mupain-1-16 in complex with murinised human uPA at pH7.4 | 分子名称: | Urokinase-type plasminogen activator, mupain-1-16, piperidine-1-carboximidamide | 著者 | Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M. | 登録日 | 2014-11-25 | 公開日 | 2015-03-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility. Plos One, 9, 2014
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4X1Q
| The crystal structure of mupain-1 in complex with murinised human uPA at pH7.4 | 分子名称: | Urokinase-type plasminogen activator, mupain-1 | 著者 | Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M. | 登録日 | 2014-11-25 | 公開日 | 2015-03-25 | 最終更新日 | 2015-11-04 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility. Plos One, 9, 2014
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4X1S
| The crystal structure of mupain-1-16-D9A in complex with murinised human uPA at pH7.4 | 分子名称: | Urokinase-type plasminogen activator, mupain-1-16, piperidine-1-carboximidamide | 著者 | Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M. | 登録日 | 2014-11-25 | 公開日 | 2015-10-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility. Plos One, 9, 2014
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4X1R
| The crystal structure of mupain-1-12 in complex with murinised human uPA at pH7.4 | 分子名称: | 1-phenylguanidine, Urokinase-type plasminogen activator, mupain-1-12 | 著者 | Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M. | 登録日 | 2014-11-25 | 公開日 | 2015-03-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility. Plos One, 9, 2014
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5GT1
| crystal structure of cbpa from L. salivarius REN | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Choline binding protein A, ... | 著者 | Jiang, L, Ren, F. | 登録日 | 2016-08-18 | 公開日 | 2017-07-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The Adhesion of Lactobacillus salivarius REN to a Human Intestinal Epithelial Cell Line Requires S-layer Proteins Sci Rep, 7, 2017
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4ZHL
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4ZHM
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5XG4
| Crystal structure of uPA in complex with quercetin | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 3,5,7,3',4'-PENTAHYDROXYFLAVONE, Urokinase-type plasminogen activator | 著者 | Jiang, L, Huang, M. | 登録日 | 2017-04-11 | 公開日 | 2017-07-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A structural mechanism of flavonoids in inhibiting serine proteases Food Funct, 8, 2017
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8J54
| Crystal structure of RXR/DR2 complex | 分子名称: | DNA (5'-D(*CP*AP*TP*GP*AP*CP*CP*TP*AP*CP*TP*GP*AP*CP*CP*TP*AP*G)-3'), DNA (5'-D(*CP*TP*AP*GP*GP*TP*CP*AP*GP*TP*AP*GP*GP*TP*CP*AP*TP*G)-3'), Retinoic acid receptor RXR, ... | 著者 | Chen, Y, Jiang, L. | 登録日 | 2023-04-21 | 公開日 | 2024-01-17 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Structural characterization of the DNA binding mechanism of retinoic acid-related orphan receptor gamma. Structure, 32, 2024
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