3B4R
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![BU of 3b4r by Molmil](/molmil-images/mine/3b4r) | Site-2 Protease from Methanocaldococcus jannaschii | 分子名称: | Putative zinc metalloprotease MJ0392, ZINC ION | 著者 | Jeffrey, P.D, Feng, L, Yan, H, Wu, Z, Yan, N, Wang, Z, Shi, Y. | 登録日 | 2007-10-24 | 公開日 | 2008-01-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure of a site-2 protease family intramembrane metalloprotease. Science, 318, 2007
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2P1L
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2PKG
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3H11
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3H4P
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![BU of 3h4p by Molmil](/molmil-images/mine/3h4p) | Proteasome 20S core particle from Methanocaldococcus jannaschii | 分子名称: | Proteasome subunit alpha, Proteasome subunit beta | 著者 | Jeffrey, P.D, Zhang, F, Hu, M, Tian, G, Zhang, P, Finley, D, Shi, Y. | 登録日 | 2009-04-20 | 公開日 | 2009-06-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii. Mol.Cell, 34, 2009
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3H13
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3H43
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![BU of 3h43 by Molmil](/molmil-images/mine/3h43) | N-terminal domain of the proteasome-activating nucleotidase of Methanocaldococcus jannaschii | 分子名称: | Proteasome-activating nucleotidase | 著者 | Jeffrey, P.D, Zhang, F, Hu, M, Tian, G, Zhang, P, Finley, D, Shi, Y. | 登録日 | 2009-04-17 | 公開日 | 2009-06-09 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii. Mol.Cell, 34, 2009
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6WB4
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![BU of 6wb4 by Molmil](/molmil-images/mine/6wb4) | Microbiome-derived Acarbose Kinase Mak1 Labeled with selenomethionine | 分子名称: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Acarbose Kinase Mak1, ... | 著者 | Jeffrey, P.D, Balaich, J.N, Estrella, M.A, Donia, M.S. | 登録日 | 2020-03-26 | 公開日 | 2021-04-21 | 最終更新日 | 2021-12-15 | 実験手法 | X-RAY DIFFRACTION (2.593 Å) | 主引用文献 | The human microbiome encodes resistance to the antidiabetic drug acarbose. Nature, 600, 2021
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6WB5
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![BU of 6wb5 by Molmil](/molmil-images/mine/6wb5) | Microbiome-derived Acarbose Kinase Mak1 as a Complex with Acarbose and AMP-PNP | 分子名称: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Acarbose Kinase Mak1, MANGANESE (II) ION, ... | 著者 | Jeffrey, P.D, Balaich, J.N, Estrella, M.A, Donia, M.S. | 登録日 | 2020-03-26 | 公開日 | 2021-04-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.102 Å) | 主引用文献 | The human microbiome encodes resistance to the antidiabetic drug acarbose. Nature, 600, 2021
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6WB7
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![BU of 6wb7 by Molmil](/molmil-images/mine/6wb7) | Acarbose Kinase AcbK as a Complex with Acarbose and AMP-PNP | 分子名称: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Acarbose 7(IV)-phosphotransferase, MANGANESE (II) ION, ... | 著者 | Jeffrey, P.D, Balaich, J.N, Estrella, M.A, Donia, M.S. | 登録日 | 2020-03-26 | 公開日 | 2021-04-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | The human microbiome encodes resistance to the antidiabetic drug acarbose. Nature, 600, 2021
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7KGX
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![BU of 7kgx by Molmil](/molmil-images/mine/7kgx) | Structure of PQS Response Protein PqsE in Complex with 4-(3-(2-methyl-2-morpholinobutyl)ureido)-N-(thiazol-2-yl)benzamide | 分子名称: | 2-aminobenzoylacetyl-CoA thioesterase, 4-({[(2R)-2-methyl-2-(morpholin-4-yl)butyl]carbamoyl}amino)-N-(1,3-thiazol-2-yl)benzamide, FE (III) ION | 著者 | Jeffrey, P.D, Taylor, I.R, Bassler, B.L. | 登録日 | 2020-10-19 | 公開日 | 2021-05-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein-Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production. Acs Chem.Biol., 16, 2021
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7KGW
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6E52
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1MJE
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![BU of 1mje by Molmil](/molmil-images/mine/1mje) | STRUCTURE OF A BRCA2-DSS1-SSDNA COMPLEX | 分子名称: | 5'-D(P*TP*TP*TP*TP*TP*T)-3', Deleted in split hand/split foot protein 1, breast cancer 2 | 著者 | Yang, H, Jeffrey, P.D, Miller, J, Kinnucan, E, Sun, Y, Thoma, N.H, Zheng, N, Chen, P.L, Lee, W.H, Pavletich, N.P. | 登録日 | 2002-08-27 | 公開日 | 2002-09-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure. Science, 297, 2002
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3CEV
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![BU of 3cev by Molmil](/molmil-images/mine/3cev) | ARGINASE FROM BACILLUS CALDEVELOX, COMPLEXED WITH L-ARGININE | 分子名称: | ARGININE, MANGANESE (II) ION, PROTEIN (ARGINASE) | 著者 | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | 登録日 | 1999-03-15 | 公開日 | 1999-04-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. Structure Fold.Des., 7, 1999
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7N29
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![BU of 7n29 by Molmil](/molmil-images/mine/7n29) | Structure of NAD kinase | 分子名称: | NAD kinase 2, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Du, J, Estrella, M.A, Jeffrey, P.D, Korennykh, A.V. | 登録日 | 2021-05-28 | 公開日 | 2022-05-04 | 最終更新日 | 2022-06-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of human NADK2 reveals atypical assembly and regulation of NAD kinases from animal mitochondria. Proc.Natl.Acad.Sci.USA, 119, 2022
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5BV0
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5BUZ
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5BV1
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4U6U
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6E95
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6PRK
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![BU of 6prk by Molmil](/molmil-images/mine/6prk) | X-ray Crystal Structure of Bacillus subtilis RicA in complex with RicF | 分子名称: | RicA, RicF | 著者 | Khaja, F.T, Jeffrey, P.D, Neiditch, M.B, Dubnau, D. | 登録日 | 2019-07-10 | 公開日 | 2019-10-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure-Function Studies of the Bacillus subtilis Ric Proteins Identify the Fe-S Cluster-Ligating Residues and Their Roles in Development and RNA Processing. Mbio, 10, 2019
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4CEV
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![BU of 4cev by Molmil](/molmil-images/mine/4cev) | ARGINASE FROM BACILLUS CALDEVELOX, L-ORNITHINE COMPLEX | 分子名称: | GUANIDINE, L-ornithine, MANGANESE (II) ION, ... | 著者 | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | 登録日 | 1999-03-15 | 公開日 | 1999-04-16 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. Structure Fold.Des., 7, 1999
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1YY9
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![BU of 1yy9 by Molmil](/molmil-images/mine/1yy9) | Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab Heavy chain, ... | 著者 | Li, S, Schmitz, K.R, Jeffrey, P.D, Wiltzius, J.J.W, Kussie, P, Ferguson, K.M. | 登録日 | 2005-02-24 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.605 Å) | 主引用文献 | Structural basis for inhibition of the epidermal growth factor receptor by cetuximab Cancer Cell, 7, 2005
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1YY8
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![BU of 1yy8 by Molmil](/molmil-images/mine/1yy8) | Crystal structure of the Fab fragment from the monoclonal antibody cetuximab/Erbitux/IMC-C225 | 分子名称: | Cetuximab Fab Heavy chain, Cetuximab Fab Light chain | 著者 | Li, S, Schmitz, K.R, Jeffrey, P.D, Wiltzius, J.J.W, Kussie, P, Ferguson, K.M. | 登録日 | 2005-02-24 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for inhibition of the epidermal growth factor receptor by cetuximab Cancer Cell, 7, 2005
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